Results 1 to 10 of about 162,609 (336)

The active metabolites of <i>Eucommia ulmoides</i> leaves alleviate atherosclerosis induced by a high-fat diet and VD3 in rats. [PDF]

Front Pharmacol
Gong M, Zhu L, Cui B, Ling C, Liu X, Wang Z, Dai L.   +6 more
europepmc   +1 more source

Benzo[a]pyrene aggravated ovalbumin‑induced epithelial tight junction disruption via ROS driven‑NLRP3/Caspase‑1 signaling pathway in asthmatic mice. [PDF]

Int J Mol Med
Xu Y, Feng Y, Wang L, Xu X, Xu L, Wang B.   +5 more
europepmc   +1 more source

Electroacupuncture and Parecoxib Reduce Inflammatory Injury in a Primary Dysmenorrhea Rat Model: Investigating the Role of the COX-2/NF-κB/NLRP3 Pathway. [PDF]

J Pain Res
Xue X, Wang S, Li J, Yuan H, Pan S, Liu X, Yue Z, Liu Y.   +7 more
europepmc   +1 more source

Natriuretic peptides as novel regulators of dendritic cells-mediated inflammation. [PDF]

Cell Mol Life Sci
Manni G, Barcelos ECS, Ricciuti D, Pieroni B, Gargaro M, Mencarelli G, Acha-Orbea H, Talesa VN, Mezzasoma L, Fallarino F.   +9 more
europepmc   +1 more source

Inhibition of NLRP3 by a CNS-penetrating indazole scaffold

Torp J, Ferber D, Buthmann H, Hagelueken G, Deshpande A, Hartman G, Hughes RE, Salazar T, Tronnes S, Duisembekova A, Marleaux M, Hochheiser IV, Coll RC, Montgomery R, Fortney K, Py BF, Wilhelmsen K, Geyer M.   +17 more
europepmc   +1 more source

UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis

Journal of Clinical Investigation, 2023
. Cellular lipid metabolism has been linked to immune responses; however, the precise mechanisms by which de novo fatty acid synthesis can regulate inflammatory responses remain unclear. The NLRP3 inflammasome serves as a platform for caspase-1–dependent
Jong-Seok Moon, Seonmin Lee, Mi-Ae Park, I. Siempos, M. Haslip, Patty J. Lee, Mijin Yun, C. Kim, J. Howrylak, S. Ryter, K. Nakahira, A. Choi   +11 more
semanticscholar   +1 more source