Results 51 to 60 of about 14,170 (209)

WHOLE GENOME SEQUENCE OF SARS-COV-2 FROM COVID-19 ACQUIRED HEMOPHILIA PATIENT

International Journal of Infectious Diseases, 2023
Intro: Acquired hemophilia is an atypical pathology of SARS-CoV-2 infection, which could be variant associated. Here, we share a sequence of the SARS-CoV-2 genome from patient with COVID-19 acquired haemophilia.
U.A. Zainulabid, A. Aslam, M. Hussain, I. Ibrahim, P. Periyasamy, N. Kamarudin, H.F. Ahmad   +6 more
doaj   +1 more source

Structure-Based High-Throughput Virtual Screening and Molecular Dynamics Simulation for the Discovery of Novel SARS-CoV-2 NSP3 Mac1 Domain Inhibitors

Viruses, 2023
Since the emergence of SARS-CoV-2, many genetic variations within its genome have been identified, but only a few mutations have been found in nonstructural proteins (NSPs).
Behnaz Yazdani, Hajar Sirous, Simone Brogi, Vincenzo Calderone   +3 more
doaj   +1 more source

Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China. [PDF]

, 2020
An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-nCoV and severe acute respiratory syndrome (SARS) or SARS-like coronaviruses.
Cheng, Genhong, Ding, Xiao, Huang, Baoying, Jiang, Taijiao, Meng, Jing, Niu, Peihua, Peng, Yousong, Quan, Lijun, Sheng, Jie, Tan, Wenjie, Wang, Jiangyuan, Wang, Xianyue, Wu, Aiping, Xia, Zanxian, Zhang, Zheng, Zhu, Zhaozhong   +15 more
core  

Evaluation of a range of mammalian and mosquito cell lines for use in Chikungunya virus research [PDF]

, 2017
Chikungunya virus (CHIKV) is becoming an increasing global health issue which has spread across the globe and as far north as southern Europe. There is currently no vaccine or anti-viral treatment available.
A Lo Presti, B Salvador, BK Dove, BM Gunn, C Caglioti, C Paupy, C Porter, C Rhein von, CB Willberg, CW Chiam, D Olagnier, D Ross-Thriepland, DE Brackney, EM Morazzani, F Deeba, F Parker, G Zhang, GM Liumbruno, GV Gee, JC Scott, KM Gallegos, L Colibus De, L Josseran, L Pohjala, LC Ng, LR Feldstein, M Mavale, M Pudney, M Sourisseau, M Varjak, MA Lawson, MU Kraemer, O Schwartz, OJ Brady, P Gérardin, R Broeckel, R Remenyi, RS Lanciotti, RWC Siu, S Burattini, S Choi, S Hover, S Mattar, SC Weaver, SC Weaver, SC Weaver, SM Rampal, SP Reid, T Macleod, Ö Cesur   +49 more
core   +2 more sources

Insighting isatin derivatives as potential antiviral agents against NSP3 of COVID-19

Chemical Papers, 2022
The world is now facing intolerable damage in all sectors of life because of the deadly COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2. The discovery and development of anti-SARS-CoV-2 drugs have become pragmatic in the time needed to fight against this pandemic.
Mubashar Ilyas, Shabbir Muhammad, Javed Iqbal, Saniyah Amin, Abdullah G. Al-Sehemi, H. Algarni, Saleh S. Alarfaji, Mohammad Y. Alshahrani, Khurshid Ayub   +8 more
openaire   +3 more sources

Knockdown of piRNA pathway proteins results in enhanced Semliki forest virus production in mosquito cells [PDF]

, 2013
The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described
Donald, Claire L., Fazakerley, John K., Fragkoudis, Rennos, Human, Stacey, Kohl, Alain, McFarlane, Melanie, Schnettler, Esther, Siu, Ricky W. C., Watson, Mick   +8 more
core   +3 more sources

Alphavirus nsP3 ADP-ribosylhydrolase Activity Disrupts Stress Granule Formation [PDF]

, 2019
ABSTRACTFormation of stress granules (SGs), cytoplasmic condensates of stalled translation initiation complexes, is regulated by post-translational protein modification. Alphaviruses interfere with SG formation in response to inhibition of host protein synthesis through the activities of nonstructural protein 3 (nsP3).
Jayabalan, Aravinth Kumar, Griffin, Diane E., Leung, Anthony K. L.   +2 more
openaire   +1 more source

Semliki Forest Virus-specific Non-structural Protein nsP3 Is a Phosphoprotein

Journal of General Virology, 1988
Antisera were raised in rabbits against fusion proteins consisting of beta-galactosidase and partial amino acid sequences of Semliki Forest virus (SFV)-specific non-structural proteins nsP1, nsP2, nsP3 and nsP4. The antisera were specific since each of them precipitated only one labelled protein of a size expected for nsP1, nsP2, nsP3 or nsP4 from ...
J, Peränen, K, Takkinen, N, Kalkkinen, L, Kääriäinen   +3 more
openaire   +2 more sources

Regulation of positive-strand RNA virus replication: The emerging role of phosphorylation. [PDF]

, 2007
Protein phosphorylation is a reversible post-translational modification that plays a fundamental role in the regulation of many cellular processes.
Jakubiec, Anna, Jupin, Isabelle
core   +3 more sources

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source