Results 91 to 100 of about 12,509 (185)

Mitotic Phosphorylation of Nucleoporins: Dismantling NPCs and Beyond [PDF]

Developmental Cell, 2011
Recently reporting in Cell, Laurell et al. (2011) demonstrate that the hyperphosphorylation of vertebrate Nup98 by distinct mitotic kinases contributes to its release from nuclear pores, drives nuclear envelope permeabilization, and may provide a molecular switch coordinating nuclear envelope breakdown and spindle formation.
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Nucleoporin-Related Leukemia: Nucleoporin rearrangements and their impact on nucleocytoplasmic transport and the proteome [PDF]

, 2020
Doctorat en ...
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Analysis of Lotus japonicus nuclear pore NUP107-160 subcomplex mutants reveals pronounced structural plasticity and functional redundancy

Frontiers in Plant Science, 2014
Mutations in the Lotus japonicus nucleoporin genes, NUP85, NUP133 and NENA (SEH1), lead to defects in plant-microbe symbiotic signaling. The homologous proteins in yeast and vertebrates are part of the conserved NUP84/NUP107-160 sub-complex, which is an ...
Andreas eBinder, Martin eParniske
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Phosphorylation of ELYS promotes its interaction with VAPB at decondensing chromosomes during mitosis

EMBO Reports
ELYS is a nucleoporin that localizes to the nuclear side of the nuclear pore complex (NPC) in interphase cells. In mitosis, it serves as an assembly platform that interacts with chromatin and then with nucleoporin subcomplexes to initiate post-mitotic ...
Christina James, Ulrike Möller, Christiane Spillner, Sabine König, Olexandr Dybkov, Henning Urlaub, Christof Lenz, Ralph H Kehlenbach   +7 more
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Nucleoporin 153 deficiency in adult neural stem cells defines a pathological protein-network signature and defective neurogenesis in a mouse model of AD

Stem Cell Research & Therapy
Background Reduction of adult hippocampal neurogenesis is an early critical event in Alzheimer’s disease (AD), contributing to progressive memory loss and cognitive decline.
Claudia Colussi, Alessia Bertozzi, Lucia Leone, Marco Rinaudo, Raimondo Sollazzo, Federica Conte, Elena Paccosi, Luca Nardella, Giuseppe Aceto, Domenica Donatella Li Puma, Cristian Ripoli, Maria Gabriella Vita, Camillo Marra, Marcello D’Ascenzo, Claudio Grassi   +14 more
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Multifunctional roles of Brl1-Brr6 in nuclear envelope fusion during nuclear pore complex biogenesis

The EMBO Journal
Brl1 and Brr6 are integral membrane proteins of the yeast nuclear envelope (NE) that transiently associate with nuclear pore complexes (NPCs). The exact roles of Brl1 and Brr6 during NPC assembly are unclear.
Sayan Mondal, Annett Neuner, Azqa Ajmal Khan, Jlenia Vitale, Elmar Schiebel   +4 more
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Nucleoporin [PDF]

, 2020
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A nucleoporin that facilitates meiotic kinetochore reorganization [PDF]

Cell Cycle, 2016
Hui-Ju, Yang, Tokuko, Haraguchi, Yasushi, Hiraoka   +2 more
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Pathologies at the gateway: exploring the link between nucleoporins and inherited diseases. [PDF]

Cell Mol Life Sci
Braun DA, Jühlen R, Krausel V, Antonin W.   +3 more
europepmc   +1 more source

Novel nucleoporin drives aggressiveness [PDF]

Nature Reviews Urology, 2018
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