Results 81 to 90 of about 14,867 (213)

Two structurally distinct domains of the nucleoporin Nup170 cooperate to tether a subset of nucleoporins to nuclear pores [PDF]

Journal of Cell Biology, 2009
How individual nucleoporins (Nups) perform their role in nuclear pore structure and function is largely unknown. In this study, we examined the structure of purified Nup170 to obtain clues about its function. We show that Nup170 adopts a crescent moon shape with two structurally distinct and separable domains, a β-propeller N terminus and an α-solenoid
Flemming, Dirk, Sarges, Phillip, Stelter, Philipp, Hellwig, Andrea, Boettcher, Bettina, Hurt, Ed   +5 more
openaire   +3 more sources

Host Factor Nucleoporin 93 Is Involved in the Nuclear Export of Influenza Virus RNA

Frontiers in Microbiology, 2018
Influenza virus replication relies on the functions of host factors. In our previous study, we identified host factors involved in virus replication and began analyses of their roles in this process.
Yuri Furusawa, Shinya Yamada, Yoshihiro Kawaoka, Yoshihiro Kawaoka, Yoshihiro Kawaoka   +4 more
doaj   +1 more source

The Cytosolic Iron–Sulfur Cluster Assembly Targeting Complex Is Hijacked by Magnaporthe Effector AvrPi9 to Suppress Rice Resistance

Plant Biotechnology Journal, EarlyView.
ABSTRACT The cytosolic iron–sulfur (Fe‐S) cluster assembly (CIA) targeting complex mediates the maturation of cytosolic and nuclear Fe‐S proteins and governs core eukaryotic cellular processes. However, whether this complex contributes to plant disease resistance remains unclear.
Huanbin Shi, Zhiquan Liu, Ying Zhang, Runjing Li, Zhizhen Fu, Ya Chen, Hui Wen, Liang Cai, Zhengting Chen, Jiehua Qiu, Yanjun Kou   +10 more
wiley   +1 more source

The nucleoporin-like protein NLP1 (hCG1) promotes CRM1-dependent nuclear protein export

, 2012
Translocation of transport complexes across the nuclear envelope is mediated by nucleoporins, proteins of the nuclear pore complex that contain phenylalanine-glycine (FG) repeats as a characteristic binding motif for transport receptors. CRM1 (exportin 1)
Waldmann, Inga, C. Spillner, I. Waldmann, Spillner, Christiane, Kehlenbach, Ralph H., R. H. Kehlenbach   +5 more
core   +1 more source

SCARB1 downregulation in adrenal insufficiency with Allgrove syndrome

Orphanet Journal of Rare Diseases, 2023
Background Allgrove disease is a rare genetic syndrome characterized by adrenal insufficiency, alacrimia, achalasia and complex neurological involvement.
Giacomo Bitetto, Gianluca Lopez, Dario Ronchi, Alessandra Pittaro, Valentina Melzi, Erika Peverelli, Fulvia Milena Cribiù, Giacomo P. Comi, Giovanna Mantovani, Alessio Di Fonzo   +9 more
doaj   +1 more source

Photoperiodism‐Specific QTLs Support Switch‐Like Genetic Control of Obligate Long‐Day Photoperiodism in Mimulus guttatus

Plant Species Biology, Volume 41, Issue 6, November 2026.
Photoperiodic flowering is well studied in facultative photoperiodism plants, but the genetic basis of obligate photoperiodism remains poorly understood. Using QTL mapping and RNA‐seq in Mimulus guttatus, we identified photoperiodism‐specific QTLs that are distinct from flowering‐time QTLs, supporting switch‐like genetic control of obligate long‐day ...
Po‐Kai Huang, Daniel E. Runcie
wiley   +1 more source

The Multiple Faces of Disordered Nucleoporins

Journal of Molecular Biology, 2016
An evolutionary advantage of intrinsically disordered proteins (IDPs) is their ability to bind a variety of folded proteins-a paradigm that is central to the nucleocytoplasmic transport mechanism, in which nuclear transport receptors mediate the translocation of various cargo through the nuclear pore complex by binding disordered phenylalanine-glycine ...
openaire   +2 more sources

NLS‐mediated NPC functions of the nucleoporin Pom121 [PDF]

FEBS Letters, 2010
MINT‐7951306, MINT‐7951362: pom121 (uniprotkb:Q5EWX9) physically interacts (MI:0914) with nup155 (uniprotkb:Q7ZWL0), nup160 (uniprotkb:P83722), nup93 (uniprotkb:Q7ZX96), Importin beta (uniprotkb:P52297) and nup62 (uniprotkb:Q91349) by pull down (MI:0096)
Yavuz, Sevil, Santarella-Mellwig, Rachel, Koch, Birgit, Jaedicke, Andreas, Mattaj, Iain W., Antonin, Wolfram   +5 more
openaire   +2 more sources

The Genome and Population Structure of the Spruce Beetle, Dendroctonus rufipennis (Kirby, 1837), a Transcontinental Pest of North American Spruce

Molecular Ecology Resources, Volume 26, Issue 8, November 2026.
ABSTRACT The spruce bark beetle Dendroctonus rufipennis (Family: Curculionidae; Subfamily Scolytinae) is a major forest insect pest throughout the transcontinental range of spruce species (Picea spp.) in North America. Here, we present an annotated, near chromosome‐level, genome assembly of 271 Mb, with 86% of the assembly contained in 16 ...
Erin O. Campbell, Philip D. Batista, Véronique Lévesque‐Tremblay, Catherine Béliveau, Kathia Bernier, Kateryna Romanenko, Ward B. Strong, Katherine P. Bleiker, Dezene P. W. Huber, Christopher I. Keeling   +9 more
wiley   +1 more source

Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C.elegans Embryos [PDF]

, 2015
During cell division, chromatin alternates between a condensed state to facilitate chromosome segregation and a decondensed form when DNA replicates.
Blow, J. Julian; id_orcid, Karim Labib, Craig, Gillian, Remi Sonneville, Labib, Karim, Sonneville, Remi, Gillian Craig, Anton Gartner, J. Julian Blow, Labib, Karim; id_orcid, Gartner, Anton, Blow, J. Julian   +11 more
core   +1 more source