Results 91 to 100 of about 29,387 (258)

OREXIN 1 AND 2 RECEPTOR INVOLVEMENT IN CO2 -INDUCED PANIC-ASSOCIATED BEHAVIOR AND AUTONOMIC RESPONSES [PDF]

open access: yes, 2015
BACKGROUND: The neuropeptides orexin A and B play a role in reward and feeding and are critical for arousal. However, it was not initially appreciated that most prepro-orexin synthesizing neurons are almost exclusively concentrated in the perifornical
Bonaventure, Pascal   +7 more
core   +1 more source

Ageing‐related modification of sleep and breathing in orexin‐knockout narcoleptic mice

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Narcolepsy type‐1 (NT1) is a lifelong sleep disease, characterised by impairment of the orexinergic system, with a typical onset during adolescence and young adulthood. Since the wake–sleep cycle physiologically changes with ageing, this study aims to compare sleep patterns between orexin‐knockout (KO) and wild type (WT) control mice at ...
Stefano Bastianini   +7 more
wiley   +1 more source

Narcolepsy and emotional experience: a review of the literature [PDF]

open access: yes, 2018
Narcolepsy is a chronic sleep disorder characterized by excessive daytime sleepiness, cataplexy, hypnagogic hallucinations, and sleep paralysis. This disease affects significantly the overall patient functioning, interfering with social, work, and ...
De Gennaro, Luigi   +4 more
core   +1 more source

Narcolepsy initially misdiagnosed as schizophrenia: A case report

open access: yes
Sleep Research, EarlyView.
Feng Daoyi, Liu Xin, Xu Rui, He Lihua
wiley   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont   +5 more
wiley   +1 more source

ラット脳室内へのオレキシン-A持続投与は明期の摂食量を増加させたが、体重増加には影響はなかった [PDF]

open access: yes, 2000
Orexins(orexin-A and -B)are recently identified neuropeptides,which are thought to be implicated in the regulation of feeding behavior. We used a NPY-Y1 receptor specific antagonist,BIBO3304,to examine whether NPY is involved in orexin-induced feeding ...
Yamanaka Akihiro, 山中 章弘
core  

Mice in ecstasy : advanced animal models in the study of MDMA [PDF]

open access: yes, 2010
The party drug 3,4-methylenedioxymethamphetamine -better known as MDMA or ecstasy- has numerous effects on the human body, characterized by a rush of energy, euphoria and empathy.
Stove, Christophe   +3 more
core   +2 more sources

Profiling the sleep architecture of ageing adults using a seven‐state continuous‐time Markov model

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep is a complex biological process regulated by networks of neurons and environmental factors. As one falls asleep, neurotransmitters from sleep–wake regulating neurones work in synergy to control the switching of different sleep states throughout the night. As sleep disorders or underlying neuropathology can manifest as irregular switching,
Jonathon Jacobs   +3 more
wiley   +1 more source

Respiratory safety of lemborexant in adult and elderly subjects with moderate‐to‐severe chronic obstructive pulmonary disease

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Lemborexant 10 mg, a dual orexin‐receptor antagonist (DORA), did not elicit respiratory depressant effects, as measured by peripheral oxygen saturation (SpO2) or apnea–hypopnea index (AHI), in subjects with moderate‐to‐severe chronic obstructive pulmonary disease (COPD).
Jocelyn Y. Cheng   +3 more
wiley   +1 more source

Behavioral aspects in children's brothers affected by Autism Spectrum Disorders [PDF]

open access: yes, 2018
Introduction: Autistic Spectrum Disorder (ASD) is a permanent and complex disability arising within the first three years of life characterized by a socio-communicative disorder and by fixed interests and repetitive behaviors.
ANGELO MONTANA   +23 more
core   +1 more source

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