Defining the organizational structure of dopamine and muscarninic acetylcholine receptors [PDF]
, 2015 No abstract ...
Alvarez-Curto, Elisa +4 more
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Neurobiology of the Orexin System and Its Potential Role in the Regulation of Hedonic Tone
Brain Sciences, 2022 Orexin peptides comprise two neuropeptides, orexin A and orexin B, that bind two G-protein coupled receptors (GPCRs), orexin receptor 1 (OXR1) and orexin receptor 2 (OXR2).
Martin A. Katzman, Matthew P. Katzman
doaj +1 more source
Orexin in the chicken hypothalamus: immunocytochemical localisation and comparison of mRNA concentrations during the day and night, and after chronic food restriction [PDF]
, 2013 In mammals Orexin-A and -B are neuropeptides involved in the hypothalamic regulation of diverse physiological functions including food intake and the sleep-wake cycle.
de Girolamo, Paolo +5 more
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Frontiers in Endocrinology, 2013 The hypothalamus monitors body homeostasis and regulates various behaviors such as feeding, thermogenesis, and sleeping. Orexins (also known as hypocretins) were identified as endogenous ligands for two orphan G-protein-coupled receptors in the lateral ...
Ayumu eInutsuka +3 more
doaj +1 more source
Expression of Orexin A and its Receptor 1 in the Epididymis of the South American Camelid Alpaca (Vicugna pacos). [PDF]
, 2013 Orexins A (ox A) and B are two peptides originally discovered in neurons of rat hypothalamus, and later found in different cellular types of the gastrointestinal and genital tracts. They arise from the proteolytic cleavage of a common precursor molecule,
DE LUCA, ADRIANA +5 more
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Frontiers in Endocrinology, 2018 Orexins (OxA and OxB) also termed hypocretins are hypothalamic neuropeptides involved in central nervous system (CNS) to control the sleep/wake process which is mediated by two G protein-coupled receptor subtypes, OX1R, and OX2R.
Alain Couvineau +6 more
doaj +1 more source
Localization of orexin B and orexin-2 receptor in the rat epididymis [PDF]
, 2018 The peptides orexin A (OXA) and orexin B (OXB) derived from the proteolytic cleavage of a common precursor molecule, prepro-orexin, were originally described in the rat hypothalamus.
Alfredo Vittoria +8 more
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Diurnal inhibition of NMDA-EPSCs at rat hippocampal mossy fibre synapses through orexin-2 receptors. [PDF]
, 2014 Diurnal release of the orexin neuropeptides orexin-A (Ox-A, hypocretin-1) and orexin-B (Ox-B, hypocretin-2) stabilises arousal, regulates energy homeostasis and contributes to cognition and learning.
Longordo, F. +4 more
core +1 more source
Neuroprotective Effects of Physical Activity: Evidence from Human and Animal Studies
Frontiers in Neurology, 2017 In the present article, we provide a review of current knowledge regarding the role played by physical activity (PA) in preventing age-related cognitive decline and reducing risk of dementia.
Sergio Chieffi +12 more
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Orexin system increases energy expenditure by brown adipose tissue activity
National Journal of Physiology, Pharmacy and Pharmacology, 2017 Adipose tissue is a biological caloric reservoir that expands itself in response to overnutrition and releases lipids in response to energy deficit. It comprises white adipose tissue, the main energy storage, and brown adipose tissue (BAT), a key site of
Antonietta Messina +11 more
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