Results 31 to 40 of about 55,714 (303)
Current Osteoporosis Reports, 2023 Abstract Purpose of Review The purpose of this review is to provide a background on osteocytes and the primary cilium, discussing the role it plays in osteocyte mechanosensing. Recent Findings Osteocytes are thought to be the primary mechanosensing cells in bone tissue ...
Verbruggen, S.W. +2 more
openaire +4 more sources
Inhibition of Cdk5 Ameliorates Skeletal Bone Loss in Glucocorticoid-Treated Mice
Biomedicines, 2022 Glucocorticoids (GCs) are widely used to treat inflammatory diseases. However, their long-term use leads to glucocorticoid-induced osteoporosis, increasing morbidity and mortality. Both anabolic and anti-resorptive drugs are used to counteract GC-induced
Benjamin Thilo Krüger +8 more
doaj +1 more source
Primary osteoblast-like cells from patients with end-stage kidney disease reflect gene expression, proliferation, and mineralization characteristics ex vivo. [PDF]
, 2015 Osteocytes regulate bone turnover and mineralization in chronic kidney disease. As osteocytes are derived from osteoblasts, alterations in osteoblast function may regulate osteoblast maturation, osteocytic transition, bone turnover, and skeletal ...
Bowen, Richard E +6 more
core +2 more sources
TNF-α Directly Enhances Osteocyte RANKL Expression and Promotes Osteoclast Formation
Frontiers in Immunology, 2019 Osteoimmunology peeks into the interaction of bone and the immune system, which has largely proved to be a multiplex reaction. Osteocytes have been shown to regulate bone resorption through the expression of RANKL in physiologic and pathologic conditions.
Aseel Marahleh +9 more
doaj +1 more source
Histological and immunohistochemical evaluation of mandibular bone tissue regeneration [PDF]
, 2018 The purpose of the study was to perform an immunohistochemical and histological evaluation of samples taken from different bone regeneration procedures in atrophic human mandible.
Brauner, E +8 more
core +1 more source
Osteocytes and Bone Metastasis [PDF]
Frontiers in Endocrinology, 2020 Bone is the most frequent site of breast cancer and prostate cancer metastasis, and one of the most common sites of metastasis for many solid tumors. Once cancer cells colonize in the bone, it imposes a major clinical challenge for the treatment of the disease, and fatality rates increase drastically.
Manuel A. Riquelme +2 more
openaire +3 more sources
Frontiers in Bioengineering and Biotechnology, 2020 Recent in vitro studies have revealed that the mechanobiological responses of osteoblasts and osteocytes are fundamentally impaired during estrogen deficiency.
Syeda Masooma Naqvi +4 more
doaj +1 more source
Isolation and culture of primary osteocytes from the long bones of skeletally mature and aged mice
BioTechniques, 2012 The purpose of this work was to establish a methodology to enable the isolation and study of osteocytes from skeletally mature young (4-month-old) and old (22-month-old) mice.
Amber Rath Stern +5 more
doaj +1 more source
Electron Microscopic Studying of Rat Bone Cells Under Microgravity Conditions [PDF]
, 2016 In the experiments on rats (SLS-2) with the use of electron microscopy there was made the study of the osteoclasts population and the peculiarities of resorptive processes in a spongy bone of the epiphyses and the iliac crest.The results of investigation
Polkovenko, O. (Olga)
core +2 more sources
The Role of Osteocytes in Inflammatory Bone Loss
Frontiers in Endocrinology, 2019 Osteoimmunology investigations to-date have demonstrated the significant interactions between bone surface cells, osteoclasts and osteoblasts, and immune cells.
Corinne E. Metzger, S. Anand Narayanan
doaj +1 more source