Results 121 to 130 of about 52,257,618 (175)

Epidemiological and genetic characteristics of clinical carbapenemase-producing Enterobacterales isolates from Batna hospitals in Algeria

BMC Infectious Diseases
Background Carbapenemase-producing Enterobacterales isolates are associated with significant mortality and have emerged as a major problem in healthcare settings worldwide.
Amel Benbouza, Ahmed Kassah-Laouar, Widad Chelaghma, Fayza Bouziane, Yassina Mebarki, Jean-Marc Rolain, Lotfi Loucif   +6 more
doaj   +1 more source

Loss of OmpK35 and Glycine-aspartic acid Duplication in ompK36 Negatively Affect the in vitro Synergy of Meropenem in Combination with Piperacillin/tazobactam or Imipenem Against OXA-48-like Carbapenemase-producing Klebsiella pneumoniae

Journal of Global Antimicrobial Resistance
BACKGROUND-AIM: Although ceftazidime/avibactam is the agent of choice in OXA-48-producing Klebsiella pneumoniae infections, it is not readily available or prohibitively expensive in many countries. Since piperacillin/tazobactam plus meropenem combination
Abdullah Tarik Aslan, Mervenur Demir, Elif Seren Tanriverdi, Budi Permana, Rhys Izuagbe, Kay A. Ramsay, Brian Forde, Baris Otlu, David L. Paterson, Patrick Harris, Murat Akova, Gulsen Hazirolan   +11 more
doaj   +1 more source

Rapid, sensitive and specific detection of OXA-48-like-producing Enterobacteriaceae by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

, 2014
International audience: The emergence of Enterobacteriaceae producing the class D carbapenemase OXA-48 has become a public health concern, particularly in southern Europe and in the Mediterranean area.
Bertrand, Xavier, Hocquet, Didier, Manzoni, Marion, Sauget, Marlène, Cabrolier, Nadège   +4 more
core   +1 more source

Emergence of NDM and OXA-48-like producing Enterobacterales in Northern Morocco

Journal of Infection in Developing Countries
Introduction: Carbapenemase-producing Enterobacterales (CPE) have widely emerged as a global health threat due to the spread of resistance genes such as New Delhi metallo-β-lactamase (blaNDM) and oxacillinase-48-like β-lactamases (blaOXA-48-like).
Majda El-Hassouni, Asmae Hazzaz, Reda A Souhli, El Mehdi El Ghorba, Hanaa El Mamouny, Kawtar El Harrak, Nouhaila Chahid, Youssra Amekran, Karima Rissoul   +8 more
doaj   +1 more source

Molecular genotyping reveals multiple carbapenemase genes and unique bla OXA-51-like (oxaAb) alleles among clinically isolated Acinetobacter baumannii from a Philippine tertiary hospital

Tropical Medicine and Health
Background Acinetobacter baumannii continued to be an important Gram-negative pathogen of concern in the clinical context. The resistance of this pathogen to carbapenems due to the production of carbapenemases is considered a global threat.
Mark B. Carascal, Raul V. Destura, Windell L. Rivera   +2 more
doaj   +1 more source

A Whole-Genome Sequencing-Based Approach for the Characterization of Klebsiella pneumoniae Co-Producing KPC and OXA-48-like Carbapenemases Circulating in Sardinia, Italy. [PDF]

Microorganisms, 2023
Del Rio A, Fox V, Muresu N, Sechi I, Cossu A, Palmieri A, Scutari R, Alteri C, Sotgiu G, Castiglia P, Piana A.   +10 more
europepmc   +1 more source

Evaluation of phenotypic methods for the detection of OXA-48-like carbapenemases in Enterobacterales [PDF]

Antecedentes: Las carbapenemasas OXA-48-like muestran una rápida expansión a nivel global, y el Perú no es ajeno a ello. La prueba gold estándar para su detección es la PCR y secuenciamiento, pero estos no son accesibles para los establecimientos de ...
Lobaton Almonacid, Gina Thalia, Baca Camacho, Karla Stefany   +1 more
core  

International and regional spread of carbapenem-resistant Klebsiella pneumoniae in Europe

Nature Communications
Carbapenem-resistant Klebsiella pneumoniae (CRKP) are of particular concern due to the spread of antibiotic resistance genes associated with mobile genetic elements.
Mabel Budia-Silva, Tomislav Kostyanev, Stefany Ayala-Montaño, Jose Bravo-Ferrer Acosta, Maria Garcia-Castillo, Rafael Cantón, Herman Goossens, Jesus Rodriguez-Baño, Hajo Grundmann, Sandra Reuter   +9 more
doaj   +1 more source

Clinical and Genomic Characterization of Carbapenem-Resistant Klebsiella pneumoniae with Concurrent Production of NDM and OXA-48-like Carbapenemases in Southern California, 2016-2022. [PDF]

Microorganisms, 2023
Cerón S, Salem-Bango Z, Contreras DA, Ranson EL, Yang S.   +4 more
europepmc   +1 more source

Diversity and function of OXA-48-like β-lactamase variants in environmental <i>Shewanella</i> isolates from Stockholm, Sweden. [PDF]

Appl Environ Microbiol
Fernández-Juárez V, Petrovic M, Mihindukulasooriya I, Joffré E, Sjöling Å, Martín-Rodríguez AJ.   +5 more
europepmc   +1 more source