Activity of RX-04 Pyrrolocytosine Protein Synthesis Inhibitors against Multidrug-Resistant Gram-Negative Bacteria [PDF]
, 2018 Pyrrolocytosines RX-04A-D are designed to bind to the bacterial 50S ribosomal subunit differently from currently-used antibiotics. The four analogs had broad anti-Gram-negative activity: RX-04A inhibited 94.7% of clinical Enterobacteriaceae ...
Doumith, Michel +4 more
core +1 more source
WGS-based characterization of trans-sectoral OXA-48-producing Escherichia coli in Switzerland
One Health AdvancesThe broad trans-sectoral (humans, animals, environment) dissemination potential of OXA-48 carbapenemase-producing Escherichia coli (OXA-48-Ec) and OXA-48-harboring plasmids represent a major One-Health concern.
Valentina Donà +9 more
doaj +1 more source
Journal of Global Antimicrobial ResistanceBACKGROUND-AIM: Although ceftazidime/avibactam is the agent of choice in OXA-48-producing Klebsiella pneumoniae infections, it is not readily available or prohibitively expensive in many countries. Since piperacillin/tazobactam plus meropenem combination
Abdullah Tarik Aslan +11 more
doaj +1 more source
Comparison of Molecular and Phenotypic Methods for the Detection and Characterization of Carbapenem Resistant Enterobacteriaceae [PDF]
, 2016 In recent years, there has been a rapid dissemination of carbapenem resistant Enterobacteriaceae (CRE). This study aimed to compare phenotypic and molecular methods for detection and characterization of CRE isolates at a large tertiary care hospital in ...
Absar, Muhammad M. +4 more
core +1 more source
Self-reported illness among Boston-area international travelers: A prospective study [PDF]
, 2016 This is the Accepted Manuscript version and was published in final edited form as: Travel Med Infect Dis. 2016 ; 14(6): 604–613. doi:10.1016/j.tmaid.2016.09.009.BACKGROUND: The Boston Area Travel Medicine Network surveyed travelers on travel-related ...
Barnett, Elizabeth D. +8 more
core +1 more source
The difficulties of identifying and treating Enterobacterales with OXA-48-like carbapenemases [PDF]
Clinical Microbiology and Infection, 2020 Kidd, James M. +2 more
openaire +3 more sources
BMC Infectious DiseasesBackground Carbapenemase-producing Enterobacterales isolates are associated with significant mortality and have emerged as a major problem in healthcare settings worldwide.
Amel Benbouza +6 more
doaj +1 more source
A greater than expected variability among OXA-48-like carbapenemases
, 2018 Introducere: Carbapenemazele OXA-48-like reprezintă o problemă majoră pentru sănătate, având învedere detectarea lor dificilă, comportamentul epidemic și tendința lor de a-și modifica spectrul de hidrolizăprin mutații punctiforme.Obiectiv: Pentru a obține o imagine amplă asupra variabilității actuale a enzimelor OXA-48-like, amrecuperat toate ...
Oueslati, Saoussen +4 more
openaire +1 more source
The performance of a resazurin chromogenic agar plate with a combined disc method for rapid screening of extended-spectrum-β-lactamases, AmpC β-lactamases and co-β-lactamases in Enterobacteriaceae. [PDF]
A resazurin chromogenic agar (RCA) along with combined disc method has been developed as a promising method for rapid screening of extended-spectrum-β-lactamase (ESBL), AmpC β-lactamase, and co-production of ESBL and AmpC.
Eumkeb, G +6 more
core +2 more sources
A Whole-Genome Sequencing-Based Approach for the Characterization of Klebsiella pneumoniae Co-Producing KPC and OXA-48-like Carbapenemases Circulating in Sardinia, Italy. [PDF]
Microorganisms, 2023 Del Rio A +10 more
europepmc +1 more source