Results 101 to 110 of about 17,417 (187)

Activity of cefiderocol against high-risk clones of multidrug-resistant Enterobacterales, Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotrophomonas maltophilia [PDF]

, 2020
BACKGROUND: Cefiderocol is a novel siderophore cephalosporin, developed for activity against MDR Gram-negative bacilli (MDR-GNB). OBJECTIVES: To assess the in vitro antibacterial activity of cefiderocol against a collection of MDR-GNB clinical ...
Conejo, Mª del Carmen, Delgado Valverde, María Mercedes, Fernández Cuenca, Felipe Manuel, Pascual Hernández, Álvaro, Serrano, Lara   +4 more
core   +1 more source

Th17 cells favor migration and invasiveness of cervical cancer cells under hypoxia in an IGF2BP2‐dependent manner

International Journal of Cancer, Volume 158, Issue 11, Page 3021-3037, 1 June 2026.
What's new? Hypoxic regions and inflammatory Th17 cells in the tumor environment are both associated with poor prognosis in cervical cancer. However, synergistic mechanisms between hypoxia and Th17 cells remain elusive. This study demonstrated Th17–hypoxia‐driven mechanisms underlying cervical cancer progression.
Selina Gies, Maike Pohlers, Tanja Tänzer, Emmanuel Ampofo, Matthias W. Laschke, Moritz Schäfer, Yoo‐Jin Kim, Rainer Maria Bohle, Erich‐Franz Solomayer, Konrad Wagner, Martin Empting, Alexandra K. Kiemer, Barbara Walch‐Rückheim   +12 more
wiley   +1 more source

Phenotypic and Genotypic Characterization of Enterobacteriaceae Producing Oxacillinase-48–Like Carbapenemases, United States

Emerging Infectious Diseases, 2018
Oxacillinase (OXA)–48–like carbapenemases remain relatively uncommon in the United States. We performed phenotypic and genotypic characterization of 30 Enterobacteriaceae producing OXA-48–like carbapenemases that were recovered from patients during 2010 ...
Joseph D. Lutgring, Wenming Zhu, Tom J.B. de Man, Johannetsy J. Avillan, Karen F. Anderson, David R. Lonsway, Lori A. Rowe, Dhwani Batra, J. Kamile Rasheed, Brandi M. Limbago   +9 more
doaj   +1 more source

First detection of Klebsiella variicola producing OXA-181 carbapenemase in fresh vegetable imported from Asia to Switzerland [PDF]

, 2015
Background: The emergence and worldwide spread of carbapenemase-producing Enterobacteriaceae is of great concern to public health services. The aim of this study was to investigate the occurrence of carbapenemase-producing Enterobacteriaceae in fresh ...
Klumpp, J., Nordmann, Patrice, Poirel, Laurent, Stephan, R., Zurfluh, K.   +4 more
core   +1 more source

Genome‐Wide In Silico Analysis of the Type VI Secretion System (T6SS) Within the Morganella Genus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
▪ Species‐specific T6SS patterns among Morganella genus (M. morganii and M. sibonii). ▪ Only one‐third of M. morganii isolates haboured a T6SS. ▪ All M. sibonii possess four T6SS clusters. ▪ M. sibonii exhibited a wide diversity of effectors compared to M. morganii.
Mathilde Duque, Aymeric Jacquemin, Delphine Girlich, Rémy A. Bonnin, Laurent Dortet   +4 more
wiley   +1 more source

Emergence of Escherichia coli producing OXA-48 β-lactamase in the community in Switzerland [PDF]

, 2016
The emergence and worldwide spread of carbapenemase-producing Enterobacteriaceae is of great concern to public health services. The aim of this study was to investigate the occurrence of carbapenemase-producing Enterobacteriaceae in the community in ...
Hächler, Herbert, Nordmann, Patrice, Nüesch-Inderbinen, Magdalena T, Poirel, Laurent, Stephan, Roger, Zurfluh, Katrin   +5 more
core  

The relative importance of large problems far away versus small problems closer to home: insights into limiting the spread of antimicrobial resistance in England [PDF]

, 2017
Background: To combat the spread of antimicrobial resistance (AMR), hospitals are advised to screen high-risk patients for carriage of antibiotic-resistant bacteria on admission.
Crook, DW, Dodgson, AR, Donker, T, Henderson, KL, Hopkins, KL, Johnson, AP, Peto, TEA, Robotham, JV, Thomas, S, Walker, AS, Woodford, N   +10 more
core   +2 more sources

Living by the lake: Plant food diversity in a prehistoric lake‐dwelling community in the Republic of North Macedonia

Archaeometry, Volume 68, Issue S2, Page S47-S68, May 2026.
Abstract This paper explores the relationship between wetland ecosystems and prehistoric lakeshore settlements within the Lake Ohrid basin (a biodiversity hotspot) by considering plant food systems at Ploča Mičov Grad, North Macedonia. The mid‐fifth millennium (c.4555–4373 to 4437–4241 cal BCE) waterlogged assemblage contained a diverse spectrum of ...
Amy Holguin, Michael Charles, Ferran Antolín, Rachel Ballantyne, Müge Ergun, Albert Hafner, Stefanie Jacomet, André F. Lotter, Goce Naumov, Johannes Reich, Raül Soteras, Elizabeth Stroud, Willy Tinner, Rachel Wood, Amy Bogaard   +14 more
wiley   +1 more source

OXA-48-Mediated Ceftazidime-Avibactam Resistance Is Associated with Evolutionary Trade-Offs

mSphere, 2019
Infections due to carbapenemase-producing Gram-negative pathogens are associated with limited treatment options and consequently lead to increased mortality and morbidity.
Christopher Fröhlich, Vidar Sørum, Ane Molden Thomassen, Pål Jarle Johnsen, Hanna-Kirsti S. Leiros, Ørjan Samuelsen   +5 more
doaj   +1 more source

Rapid identification of carbapenemase-producing enterobacteriaceae: comparison of two cultivation methods [PDF]

, 2015
We evaluated the performance of chromID CARBA compared with direct plating onto MacConkey agar supplemented with meropenem disk (MCM) for the screening and detection of carbapenemase-producing Enterobacteriaceae (CPE) from rectal swabs. Sensitivity and
Barozzi, Agostino, Fregni, Sandra, Gargiulo, Raffaele, Giovanelli, Ilaria, Mucci, Anna, Pascuzzi, Maria Valeria, SABIA, Carla, Sarti, Mario, Zirilli, Maria Olga   +8 more
core   +1 more source