Results 21 to 30 of about 11,559 (254)

Weak Intermolecular Interactions in a Series of Bioactive Oxazoles

Molecules, 2021
The intermolecular interactions in a series of nine similar 4,5-phenyl-oxazoles were studied on the basis of crystal structures determined by X-ray diffraction. The crystal architectures were analyzed for the importance and hierarchies of different, weak
Anita M. Grześkiewicz, Tomasz Stefański, Maciej Kubicki   +2 more
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Isomerization of 5-(2H-Azirin-2-yl)oxazoles: An Atom-Economic Approach to 4H-Pyrrolo[2,3-d]oxazoles

Molecules, 2021
An atom economical method for the preparation of variously substituted 4H-pyrrolo[2,3-d]oxazoles was developed on the basis of thermal isomerization of 5-(2H-azirin-2-yl)oxazoles.
Timur O. Zanakhov, Ekaterina E. Galenko, Mariya A. Kryukova, Mikhail S. Novikov, Alexander A. Khlebnikov   +4 more
doaj   +1 more source

Development of a method for the synthesis of 2,4,5-trisubstituted oxazoles composed of carboxylic acid, amino acid, and boronic acid

Beilstein Journal of Organic Chemistry, 2017
A novel method for the synthesis of trisubstituted oxazoles via a one-pot oxazole synthesis/Suzuki–Miyaura coupling sequence has been developed.
Kohei Yamada, Naoto Kamimura, Munetaka Kunishima   +2 more
doaj   +1 more source

Sir John Cornforth AC CBE FRS: his synthetic work [PDF]

, 2015
Sir John Cornforth’s work on the synthesis of cholesterol and penicillamine, on the chemistry of oxazoles, the stereochemistry of the synthesis of alkenes, the synthesis of abscisic acid and of dibenzophospholes as mimics of enzyme action, is ...
Abraham E.P., Abraham E.P., Abraham E.P., Callow R.K., Cardwell H.M.E., Cornforth J.W., Cornforth J.W., Cornforth J.W., Cornforth J.W., Cornforth J.W., Cornforth J.W., Cornforth J.W., Cornforth J.W., Cornforth J.W., James R. Hanson, Rupert Purchase   +15 more
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Synthesis of 1,3-Oxazoles via Van Leusen Reaction in a Pressure Reactor and Preliminary Studies of Cations Recognition

Proceedings, 2019
Six 1,3-oxazoles were synthetized in moderate to good yields by Van Leusen reaction in a pressure reactor. The methodology allowed to decrease the reaction times reported in the literature from hours to 20 min.
Verónica G. García-Ramírez, Claudia Contreras-Celedón, Gabriela Rodriguez-García, Luis Chacón-García, Carlos J. Cortes-García   +4 more
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Photoactivatable prodrugs of butyric acid based on new coumarin fused oxazole heterocycles [PDF]

, 2017
New coumarin fused oxazoles were investigated as photosensitive units for carboxylic acid groups using butyric acid as a model compound. 6-Oxo-6H-benzopyrano[6,7-d]oxazol-8-yl)methyl derivatives possessing various (hetero)aromatic substituents at ...
Ana M.S. Soares, Brieke, Dore, Fernandes, Fernandes, Fernandes, Fonseca, Furuta, Ghosh, Givens, Graham Hungerford, Hungerford, Kim, Klán, Lakowicz, Lavis, Lee, Loudwig, M. Sameiro T. Gonçalves, Miller, Morris, Muller, Nguyen, Nudelman, Nudelman, Piloto, Piloto, Piloto, Santini, Shell, Soares, Soares, Soares, Soares, Soares, Susana P.G. Costa, Vidali   +36 more
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Diazocarbonyl and Related Compounds in the Synthesis of Azoles

Molecules, 2021
Diazocarbonyl compounds have found numerous applications in many areas of chemistry. Among the most developed fields of diazo chemistry is the preparation of azoles from diazo compounds.
Anton Budeev, Grigory Kantin, Dmitry Dar’in, Mikhail Krasavin   +3 more
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Repositioning Antitubercular 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazoles for Neglected Tropical Diseases: Structure-Activity Studies on a Preclinical Candidate for Visceral Leishmaniasis. [PDF]

, 2016
6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazole derivatives were initially studied for tuberculosis within a backup program for the clinical trial agent pretomanid (PA-824).
Blaser, Adrian, Denny, William A, Franzblau, Scott G, Gupta, Suman, Launay, Delphine, Ma, Zhenkun, Maes, Louis, Martin, Denis, O'Connor, Patrick D, Thompson, Andrew M, Wan, Baojie, Wang, Yuehong, Yardley, Vanessa   +12 more
core   +3 more sources

Naturally Occurring Oxazole-Containing Peptides [PDF]

Marine Drugs, 2020
Oxazole-containing peptides are mostly of marine origin and they form an intriguing family with a broad range of biological activities. Here we classify these peptides on the basis of their chemical structure and discuss a number of representatives of each class that reflect the extraordinary potential of this family as a source of new drugs.
Jessica T. Mhlongo, Edikarlos Brasil, Beatriz G. de la Torre, Fernando Albericio   +3 more
openaire   +3 more sources

Continuous multistep synthesis of 2-(azidomethyl)oxazoles

Beilstein Journal of Organic Chemistry, 2018
An efficient three-step protocol was developed to produce 2-(azidomethyl)oxazoles from vinyl azides in a continuous-flow process. The general synthetic strategy involves a thermolysis of vinyl azides to generate azirines, which react with bromoacetyl ...
Thaís A. Rossa, Nícolas S. Suveges, Marcus M. Sá, David Cantillo, C. Oliver Kappe   +4 more
doaj   +1 more source