Optimization of anti-proliferative activity using a screening approach with a series of bis-heterocyclic G-quadruplex ligands [PDF]
, 2013 Using a phenotypic screening and SAR optimization approach, a phenyl-bis-oxazole derivative has been identified with anti-proliferative activity, optimized with the use of a panel of cancer cell lines.
CIANCIMINO, Cristina +4 more
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Gold Catalyzed Multicomponent Reactions beyond A3 Coupling
Molecules, 2018 The preparation of complex architectures has inspired the search for new methods and new processes in organic synthesis. Multicomponent reactions have become an interesting approach to achieve such molecular diversity and complexity.
Renso Visbal +3 more
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Molecules, 2022 An efficient, versatile, and one-pot method for the preparation of novel fluorinated thiazolo- and oxazolo[3,2-a]pyrimidin-7-ones is described from 2-aminothiazoles or 2-amino-oxazoles and fluorinated alkynoates.
Wafa Blancou +4 more
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sp3–sp3 carbon–carbon bonds formation using 2-alkylazoles and a bromoacrylate as the reaction partners [PDF]
, 2015 International ...
Bruneau, Christian +4 more
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Structure of the cyanobactin oxidase ThcOx from Cyanothece sp. PCC 7425, the first structure to be solved at Diamond Light Source beamline I23 by means of S-SAD [PDF]
, 2016 Acknowledgements We thank Diamond Light Source for providing access to beamline I23. We also thank Thomas Sorensen and his staff for access to and support on beamline I02.
Bent, Andrew F +8 more
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Total synthesis of the post-translationally modified polyazole peptide antibiotic goadsporin [PDF]
, 2017 The structurally unique polyazole antibiotic goadsporin contains six heteroaromatic oxazole and thiazole rings integrated into a linear array of amino acids that also contains two dehydroalanine residues.
Arnison +22 more
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1,4- Addition of diazomethane to a heterodiene: a direct preparation of the oxazolic ring
Anais da Academia Brasileira de Ciências, 2007 The reaction of naphthoquinone-oximes (3) and (4) with diazomethane yields directly, in one step, the oxazoles (5) and (6), respectively.A reação das naphthoquinona-oximas (3) e (4) com diazometano fornece diretamente, em uma etapa, os oxazóis (5) e (6),
Flávio da S. Emery +9 more
doaj +1 more source
2-(3-Bromophenyl)imidazo[2,1-b]oxazole
Molbank, 2023 The microwave-assisted reaction of 2-nitroimidazole with 3-bromophenacyl bromide in the presence of potassium carbonate as a base and dimethylformamide as a solvent afforded 2-(3-bromophenyl)imidazo[2,1-b]oxazole.
Ángel Cores +2 more
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Identification and isolation of insecticidal oxazoles from Pseudomonas spp.
Beilstein Journal of Organic Chemistry, 2012 Two new and five known oxazoles were identified from two different Pseudomonas strains in addition to the known pyrones pseudopyronine A and B. Labeling experiments confirmed their structures and gave initial evidence for a novel biosynthesis pathway of ...
Florian Grundmann +7 more
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Synthesis of 2,6-bis-(oxazolyl)pyridine ligands for luminescent Ln(III) complexes [PDF]
, 2012 Submitted to the European Journal of Organic ChemistryNew bis-(oxazolyl)pyridine ligands for Ln(III) ions were prepared using a expeditious methodology from threonine and dipicolinic acid chloride.
Castanheira, Elisabete M. S. +4 more
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