Results 61 to 70 of about 14,648 (255)
Organic Letters, 2018 A novel approach to trisubstituted oxazoles has been developed that is based upon an iodine-mediated aerobic oxidative cyclization of enaminone derivatives.
Yunxiang Weng +4 more
semanticscholar +1 more source
Asian Journal of Organic Chemistry, EarlyView.(Z)‐2‐oxazolines are available in a stereoselective fashion by cyclization of propargylic amides with internal triple bonds in the presence of HCl generated in situ from hexafluoroisopropanol (HFIP) and TMSCl. Response surface methodology was crucial to optimize the reaction conditions.
Nicholas Jankowski, Norbert Krause
wiley +1 more source
Synthesis and in vitro antiprotozoal activity of some 2- amino-4-phenyloxazole derivatives [PDF]
, 2017 Purpose: To prepare some 2-amino-4-(p-substituted phenyl)-oxazole derivatives and to evaluate their in vitro antiprotozoal activity against Giardia lamblia and Trichomonas vaginalis.Methods: The 2-amino-4-(p-substituted phenyl)-oxazoles (a-g) were ...
Carballo, Rubén M. +7 more
core +2 more sources
Arabian Journal of Chemistry, 2014 A new class of amido sulfonamido methane linked bis heterocycles- bis-oxazoles, thiazoles and imidazoles were prepared and screened for antimicrobial and anticancer activities.
Chokkappagari Premakumari +6 more
doaj +1 more source
Copper-Catalyzed Oxygenation Approach to Oxazoles from Amines, Alkynes, and Molecular Oxygen.
Organic Letters, 2018 A novel and efficient oxygenation approach to trisubstituted oxazoles via a copper-catalyzed aerobic oxidative dehydrogenative annulation of amines, alkynes, and O2 has been developed.
Jun Pan +4 more
semanticscholar +1 more source
Indole Synthesis via Allenyl Ester; Enantioselective Total Synthesis of Geissoschizoline
ChemistryEurope, EarlyView.An indole synthesis via an allenyl ester intermediate at ambient temperature has been developed. The mild reaction conditions allow the use of a broad range of substrates. Notably, the utility of this approach is demonstrated through the asymmetric total synthesis of geissoschizoline, a Strychnos‐type monoterpenoid indole alkaloid.
Sohsuke Moriue +5 more
wiley +1 more source
Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †. [PDF]
, 2019 Bengazoles A⁻G from the marine sponge Jaspis sp. exhibit potent in vitro antifungal activity against Candida spp. and other pathogenic fungi. The mechanism of action (MOA) of bengazole A was explored in Candida albicans under both liquid culture and ...
Cheng, Tina +3 more
core
Optimization of anti-proliferative activity using a screening approach with a series of bis-heterocyclic G-quadruplex ligands [PDF]
, 2013 Using a phenotypic screening and SAR optimization approach, a phenyl-bis-oxazole derivative has been identified with anti-proliferative activity, optimized with the use of a panel of cancer cell lines.
CIANCIMINO, Cristina +4 more
core +1 more source
Alkynyl Thioethers in Gold‐Catalyzed Annulations To Form Oxazoles
Angewandte Chemie, 2017 Non‐oxidative, regioselective, and convergent access to densely functionalized oxazoles is realized in a functional‐group tolerant manner using alkynyl thioethers.
R. Reddy +2 more
semanticscholar +1 more source
Chemistry – A European Journal, EarlyView.Fused nitrogen‐bridgehead N,O‐acetals receive specific emphasis as pivotal scaffolds due to their significant role in the bioactivity of medicinally relevant molecules. Significant approaches have been reported on their role as key synthetic building blocks/motifs in the construction of complex organic molecules and their utility as chiral auxiliaries ...
Alexis D. Kouvelas +2 more
wiley +1 more source