Results 61 to 70 of about 33,843 (263)
Complete Genome Sequencing of Field Isolates of Peste des Petits Ruminants Virus from Tanzania Revealed a High Nucleotide Identity with Lineage III PPR Viruses
Animals, 2021 Peste des petits ruminants virus (PPRV) causes a highly devastating disease of sheep and goats that threatens food security, small ruminant production and susceptible endangered wild ruminants.Edson Kinimi, Mana Mahapatra, Tebogo Kgotlele, Mariam R. Makange, Chandana Tennakoon, Felix Njeumi, Steven Odongo, Serge Muyldermans, Richard Kock, Satya Parida, Mark Rweyemamu, Gerald Misinzo +11 moredoaj +1 more sourceComparison of R9.4.1/Kit10 and R10/Kit12 Oxford Nanopore flowcells and chemistries in bacterial genome reconstruction
, 2023 Complete, accurate, cost-effective, and high-throughput reconstruction of bacterial genomes for large-scale genomic epidemiological studies is currently only possible with hybrid assembly, combining long- (typically using nanopore sequencing) and short ...Street, teresa, Stoesser, Nicole, Crook, derrick, Rodger, gillian, Sanderson, Nicholas, Kapel, Natalia, Peto, Timothy, Lipworth, samuel, Webster, Hermione +8 morecore +1 more sourceTranslational Gap in Biomarker Discovery: Tumor Surface Markers Rarely Mirror Circulating Levels
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background
Tumor‐associated cell surface proteins are frequently proposed as circulating biomarkers for colorectal cancer (CRC) based on their high tumor expression. However, many candidates identified through tissue‐based analyses fail to translate into clinically useful biomarkers.Junko Mukohyama, Shohei F. Fujita, Xinyi Fu, Shigenori Suzuki, Hiroki Hamamoto, Dai Shida, Kimihiro Yamashita, Kohei Taniguchi, Sang‐Woong Lee, Akihide Yoshimi +9 morewiley +1 more sourceThe second ever Oxford Nanopore read published
, 2014 To our knowledge this is the second Oxford Nanopore read published. This read defines some completely uninteresting features including a 30S ribosomal subunit protein S1 and an integration host factor.Audrey Farbos (579006), Paul O'Neill (513635), Konrad Paszkiewicz (577690), Karen Moore (579005) +3 morecore +1 more sourceFiltered Oxford Nanopore reads used for the ‘Malling Jewel’ and ‘Autumn Bliss’ genome sequence assemblies.
, 2023 Filtered Oxford Nanopore reads used for the ‘Malling Jewel’ and ‘Autumn Bliss’ genome sequence assemblies.Nada Šurbanovski (427477), Daniel James Sargent (10844461), R. Jordan Price (15503510), Charlotte F. Nellist (5811182), Samantha Lynn (15503516), Felicidad Fernandéz Fernandéz (15503513), Dag Røen (8734020), Helen J. Bates (8710197), Muath Alsheikh (798906), Jahn Davik (798905), Matteo Buti (3454244), Richard J. Harrison (2605258) +11 morecore +1 more sourceUnraveling a Diagnostic Enigma: A TECPR2 Case Solved Through Multi‐Omic Genomics
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT
TECPR2 is a key regulator of autophagy, encoded by the TECPR2 gene. Pathogenic variants in this gene have been linked to a rare hereditary sensory and autonomic neuropathy with intellectual disability (HSAN9). We report a teenage female with a syndromic intellectual disability disorder associated with neuromuscular abnormalities.Teresa Zhao, Andrew P. Fennell, Tanavi Sharma, Katrina M. Bell, Monique Dunstan, Sebastian Lunke, Meagan J. McGrath, Catriona McLean, Undiagnosed Diseases Network (UDN‐Aus), Alison Yeung, Anna Hackett, Anne Baxter, Ansley Morrish, Ashil Davawala, Azure Hermes, Ben Kamien, Ben Lundie, Carolyn Ellaway, Carolyn Shalhoub, Cas Simons, Cassandra Gray, Cathryn Poulton, Chloe Cunningham, Chris Barnett, Chris Richmond, Christopher Richards, Daniel MacArthur, Daniel Pavlic, Daniella Hock, Daniz Kooshavar, David Amor, David Mowat, Edward Formaini, Elaine Zhang, Ella Wilkins, Ella Zurita, Ellenore Martin, Elly Lynch, Emma Krzesinski, Emma Palmer, Esther Pierini, Evanthia O. Madelli, Francisco Santos Gonzalez, Gareth Baynam, Gunjan Garg, Hamish Scott, Hannah Thomson, Himanshu Goel, Ilias Goranitis, Ira Deveson, Isabella Pfundt, Jacqui Russell, Janine Smith, Jason Pinner, Julia Broadbent, Julie McGaughran, Karin Kassahn, Katherine Lewis, Kaustuv Bhattacharya, Kirsten Boggs, Kirsty West, Kristi Jones, Laura Wedd, Lauren Dreyer, Leah Frajman, Leanne Baxter, Lilian Downie, Lily Loughman, Lisa Bristowe, Lisa Ewans, Louise Cilento, Lucy Kevin, Lyndal Douglas, Madeleine Harris, Maie Walsh, Manisha Chauhan, Margit Shah, Martin Delatycki, Mathew Wallis, Matthew Hunter, Megan Ball, Megan Higgins, Meutia Kumaheri, Michael Fahey, Mike Field, Mohammadreza Hajjari, Natalie Stewart, Natalie Tan, Natasha Brown, Nicole Van Bergen, Noelia Nunez‐Martinez, Oliver Heath, Rachel Austin, Rani Sachdev, Rebecca Macintosh, Rebecca Vink, Rocio Rius, Ruvi Samarasekera, Ryan Pysar, Sandra Cooper, Sarah Casauria, Sarah Collinson, Sarah Jelenich, Sarah Josephi‐Taylor, Sarah Sandaradura, Sean Massey, Shannon Leblanc, Shuxiang Goh, Simon Bodek, Simon Sadedin, Simran Kaur, Smitha Kumble, Sue White, Suzanne Sallevelt, Tegan Stait, Tiffany Boughtwood, Tim Sikora, Timo Lassmann, Tiong Tan, Tracy Dudding, David R. Thorburn, David A. Stroud, John Christodoulou +122 morewiley +1 more sourceEnhancing CYP2D6 genotyping with nanopore sequencing to address allele diversity P. vivax malaria elimination
Scientific ReportsThe precise profiling of CYP2D6 alleles is critical for identifying patients who are likely to benefit from primaquine therapy, a standard treatment for preventing P. vivax relapse and, as a result, obstacle for malaria elimination.Thidathip Wongsurawat, Piroon Jenjaroenpun, Kanokon Suwannasin, Natnicha Wankaew, Naphat Sanguansakpakdee, Thananya Amornpornviwat, Arjen M. Dondorp, Nicholas P. J. Day, Francois Nosten, Nicholas J. White, Mallika Imwong +10 moredoaj +1 more sourceThe second Oxford Nanopore read ever published
, 2014 To our knowledge this is the second Oxford Nanopore read published. This read defines some completely uninteresting features including a 30S ribosomal subunit protein S1 and an integration host factor.Audrey Farbos (579006), Paul O'Neill (513635), Konrad Paszkiewicz (577690), Karen Moore (579005) +3 morecore +1 more sourceBasic sequencing matrices for Illumina and Oxford Nanopore (ONT) outputs of 37.
, 2022 Basic sequencing matrices for Illumina and Oxford Nanopore (ONT) outputs of 37.Deshni Jayathilaka (8686467), Chandima Jeewandara (455011), Ayesha Wijesinghe (8441412), Diyanath Ranasinghe (11439487), Dinuka Guruge (11662850), Dumni Gunasinghe (12342570), Tibutius Thanesh Pramanayagam Jayadas (12342564), Ruwan Wijayamuni (11662874), Gathsaurie Neelika Malavige (8441421), Osanda Dissanayake (12342567), Dinuka Ariyaratne (721988), Laksiri Gomes (296923) +11 morecore +1 more sourceOne‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor
Animal Models and Experimental Medicine, EarlyView.We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...Xu Zhang, Keru Li, Lei Tan, Wei Chen, Shan Gao, Chenyang Liu, Shuo Pan, Jiayue He, Ning Liu, Gefan Wan, Wei Dong, Weining Kong, Bin Shen, Xiaolong Qi, Yuanwu Ma +14 morewiley +1 more source
