Results 71 to 80 of about 33,843 (263)

Rapid prenatal CNV detection using nanopore technology

BMC Research Notes
Rapid identification of copy-number variations (CNVs) is crucial in prenatal diagnosis; however, current chromosomal microarray analysis (CMA) has a lengthy turnaround time. We evaluated the feasibility of low-pass nanopore sequencing for genome-wide CNV
Maolee Bhuwapathanapun, Piya Chaemsaithong, Puntabut Warintaksa, Budsaba Rerkamnuaychoke, Rachanee Parinayok, Takol Chareonsirisuthigul, Suwatcharaporn Hadradchai, Maneerat Prakobpanich, Weerin Thammachote, Natini Jinawath, Tantip Arigul, Pattaraporn Nimsamer, Sopacha Arayamethakorn, Sorawee Kaewkarn, Piroon Jenjaroenpun, Thidathip Wongsurawat   +15 more
doaj   +1 more source

Voltage Gating of a Biomimetic Nanopore: Electrowetting of a Hydrophobic Barrier

, 2017
It is desirable that nanopores that are components of biosensors are gated, i.e., capable of controllable switching between closed (impermeable) and open (permeable) states.
Song, Chen, E. Jayne Wallace, Wallace, E. Jayne, Wallace, EJ, Chen Song (216175), Trick, Jemma L., Mark S. P. Sansom, Jemma L. Trick, Song, C, E. Jayne Wallace (1659106), Sansom, Mark S. P., Sansom, Mark S.P., Mark S. P. Sansom (147715), Trick, JL, Sansom, MSP, Jemma L. Trick (3719260), Chen Song   +16 more
core   +1 more source

Monoallelic POLR3A Variants Cause Early‐Onset Peripheral Neuropathy

Annals of Neurology, EarlyView.
Objective Biallelic variants in genes encoding the RNA polymerase III complex (Pol III) cause a spectrum of neurological disorders primarily affecting the central nervous system. Monoallelic variants have been reported in the POLR3B subunit only, associated with neurodevelopmental disorder, epilepsy, and peripheral neuropathy.
Luiza L. P. Ramos, Jevin M. Parmar, Robin Wijngaard, Bianca R. Grosz, Tamas Lazar, Ligia Mateiu, Steve Vucic, Kishore R. Kumar, Dennis Yeow, Laura I. Rudaks, Lonneke de Boer, Annemarie de Vreugd, David A. Koolen, Thatjana Gardeitchik, Anita Cairns, Krishnan Iyengar, Fernando Kok, Fernanda Barbosa Figueiredo, Alzira Alves de Siqueira Carvalho, Luiz S. Mageste Barbosa, Rodrigo Rezende Arantes, Tyler Rehbein, Jordan E. Bontrager, Elizabeth P. Wood, Janet E. Sowden, Gavin Monahan, Meutia Kumaheri, Ivy Cuijt, Melina Ellis, Gonzalo Perez‐Siles, Elyshia McNamara, Ronald van Beek, Celine B. Meijers, Ivaylo Tournev, Stephan Zuchner, Shoshana J. Wodak, Clara D. M. van Karnebeek, Nigel Laing, Liana N. Semcesen, David A. Stroud, David N. Herrmann, Velina Guergueltcheva, Marina L. Kennerson, Machteld M. Oud, Gianina Ravenscroft, Ayse Candayan, Albena Jordanova   +46 more
wiley   +1 more source

Improving droplet interface platforms for nanopore sensing

Nanopore sensors have emerged since their conception 3 decades ago as a versatile, bio- inspired tool by which to conduct single-molecule investigations of DNA, and more recently proteins, RNA, methylated DNA and other polymers.
Rogers-Simmonds, Daisy
core   +1 more source

BulkVis: a graphical viewer for Oxford nanopore bulk FAST5 files [PDF]

, 2018
Motivation: The Oxford Nanopore Technologies (ONT) MinION is used for sequencing a wide variety of sample types with diverse methods of sample extraction.
Payne, Alexander, Nadine Holmes, Rakyan, Vardhman, Alexander Payne, Vardhman Rakyan, Matthew Loose, Holmes, Nadine, Loose, Matthew   +7 more
core   +1 more source

Sequencing Genome in a Bottle samples

, 2023
<p>We are pleased to announce the release of a new addition to the Oxford Nanopore Open Data project: sequencing of several Genome in a Bottle samples (including the Ashkenazi Trio). Sequencing was performed with the 5 kHz upgrade to the <a
Oxford Nanopore Technologies
core   +1 more source

Synergistic Physicochemical Inhibition of Reactive Shale Formations Using Hydrothermally Synthesized Hydroxyapatite Nickel Tungstate Nanocomposites in Water‐Based Drilling Fluids

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Wellbore instability driven by the volumetric expansion of reactive shale formations remains a primary operational challenge in modern drilling engineering, causing severe mechanical failures and substantial economic deficits. The objective of this study is to formulate and evaluate a novel dual‐action chemical additive capable of ...
Ghaleb Oriquat, Basim Abdul Alrhym, A. C. Umamaheshwer Rao, Shivam P. Chaudhary, Pardeep Singh Bains, Ripendeep Singh, Murotov Nurshod, Rasulbek Eshmetov, Ahmad Abumalek   +8 more
wiley   +1 more source

De novo yeast genome assemblies from MinION, PacBio and MiSeq platforms

Scientific Reports, 2017
Long-read sequencing technologies such as Pacific Biosciences and Oxford Nanopore MinION are capable of producing long sequencing reads with average fragment lengths of over 10,000 base-pairs and maximum lengths reaching 100,000 base- pairs.
Francesca Giordano, Louise Aigrain, Michael A Quail, Paul Coupland, James K Bonfield, Robert M Davies, German Tischler, David K Jackson, Thomas M Keane, Jing Li, Jia-Xing Yue, Gianni Liti, Richard Durbin, Zemin Ning   +13 more
doaj   +1 more source

Example read from Oxford Nanopore MinION R7 Chemistry

, 2014
An example 12,017 base-pair read from Oxford Nanopore MinION running R7 chemistry from an isolate of Salmonella enterica serovar Enteritidis, with accompanying BLAST alignment. Read accuracy is approximately 80%.
Nicholas Loman (98608), Josh Quick (576005)   +1 more
core   +1 more source

An End-to-end Oxford Nanopore Basecaller Using Convolution-augmented Transformer

, 2020
Oxford Nanopore sequencing is fastly becoming an active field in genomics, and it's critical to basecall nucleotide sequences from the complex electrical signals. Many efforts have been devoted to developing new basecalling tools over the years. However,
Chen, Z, Xuan Lv, Yutong Lu, Lu, Y, Yuedong Yang, Yang, Y, Zhiguang Chen, Lv, X   +7 more
core   +1 more source