Results 81 to 90 of about 5,800,592 (273)

Rapid prenatal CNV detection using nanopore technology

BMC Research Notes
Rapid identification of copy-number variations (CNVs) is crucial in prenatal diagnosis; however, current chromosomal microarray analysis (CMA) has a lengthy turnaround time. We evaluated the feasibility of low-pass nanopore sequencing for genome-wide CNV
Maolee Bhuwapathanapun, Piya Chaemsaithong, Puntabut Warintaksa, Budsaba Rerkamnuaychoke, Rachanee Parinayok, Takol Chareonsirisuthigul, Suwatcharaporn Hadradchai, Maneerat Prakobpanich, Weerin Thammachote, Natini Jinawath, Tantip Arigul, Pattaraporn Nimsamer, Sopacha Arayamethakorn, Sorawee Kaewkarn, Piroon Jenjaroenpun, Thidathip Wongsurawat   +15 more
doaj   +1 more source

Oxford Nanopore Sequencing (raw sequence data)

, 2020
Genome Sequencing for outbreaks ...
Ferreira, Fabienne, Aamot, Hege Vangstein   +1 more
openaire   +1 more source

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

International Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer, Morghan C. Lucas, Vitus Prokosch, Thomas Keßler, Thomas Risch, Andreas Laner, Jan Henkel, Anna Benet‐Pagès, Ariane Hallermayr, Verena Steinke‐Lange, Elke Holinski‐Feder, Barbara Klink   +11 more
wiley   +1 more source

Oxford learner's pocket dictionary (fourth edition) tahun 2011

, 2011
Learn the most important word and find new words in this updated pocket dictionary. Recommended for intermediate to advanced learners.1. 100s of new words explained (carbon footprint, fair trade, podcast, landline..)2. Oxford 300 TM keywords show you the
Oxford university press.
core   +1 more source

Enhancing CYP2D6 genotyping with nanopore sequencing to address allele diversity P. vivax malaria elimination

Scientific Reports
The precise profiling of CYP2D6 alleles is critical for identifying patients who are likely to benefit from primaquine therapy, a standard treatment for preventing P. vivax relapse and, as a result, obstacle for malaria elimination.
Thidathip Wongsurawat, Piroon Jenjaroenpun, Kanokon Suwannasin, Natnicha Wankaew, Naphat Sanguansakpakdee, Thananya Amornpornviwat, Arjen M. Dondorp, Nicholas P. J. Day, Francois Nosten, Nicholas J. White, Mallika Imwong   +10 more
doaj   +1 more source

Voltage Gating of a Biomimetic Nanopore: Electrowetting of a Hydrophobic Barrier [PDF]

, 2017
It is desirable that nanopores that are components of biosensors are gated, i.e., capable of controllable switching between closed (impermeable) and open (permeable) states.
Song, Chen, E. Jayne Wallace, Wallace, E. Jayne, Wallace, EJ, Chen Song (216175), Trick, Jemma L., Mark S. P. Sansom, Jemma L. Trick, Song, C, E. Jayne Wallace (1659106), Sansom, Mark S. P., Sansom, Mark S.P., Mark S. P. Sansom (147715), Trick, JL, Sansom, MSP, Jemma L. Trick (3719260), Chen Song   +16 more
core   +1 more source

Long‐Read Pan‐Cancer Transcriptomics Unravel Distinct Alteration Trends Between Gene and Isoform Expression in Tumorigenesis

iMetaMed, EarlyView.
Long‐read profiling of 144 tumor‐normal pairs identifies isoform‐level cancer dysregulation independent of gene changes. Our scoring system prioritizes isoform‐driven prognostic genes across cancers. ABSTRACT Tumorigenesis involves transcriptomic alterations at both gene and isoform levels.
Yuying Ding, Bo Wu, Dan Zhou, Qiang Li, Dingru Li, Mengyun Cai, Zhiyan Chen, Caimei Zhong, ChuanLe Xiao, Yuhua Deng   +9 more
wiley   +1 more source

Phytophthora capsici genome assembly for two isolates using long-read Oxford Nanopore Technology sequencing

, 2023
International audienceThe oomycete Phytophthora capsici is a common pathogen of the Solanaceae and Cucurbitaceae families. An improved assembly for the reference isolate LT1534 was constructed using Oxford Nanopore Technologies and Illumina data ...
Lefebvre, Véronique, Lagnel, Jacques, Touhami, Nasradin, Lopez-Roques, Céline, Sayeh, Amalia, Bouchez, Olivier, Szadkowski, Emmanuel   +6 more
core   +1 more source

Sorghum T2T pangenome highlights comprehensive genomic variation

iMetaOmics, EarlyView.
Three newly assembled telomere‐to‐telomere (T2T) genomes representing wild, landrace, and transformable germplasm were integrated with seven publicly available T2T genomes to construct a graph‐based pangenome. Comparative analyses revealed extensive centromere divergence, including distinct CEN137 monomer and CEN274 dimer organization, and showed that ...
Lihua Wang, Chuanzheng Wei, Hope O. Okunbor, Xiaofei Deng, Die Hu, Yongfei Wang, Junli Du, Ephrem Habyarimana, Yongfu Tao, Yi‐Hong Wang, Jieqin Li   +10 more
wiley   +1 more source

Improving droplet interface platforms for nanopore sensing

Nanopore sensors have emerged since their conception 3 decades ago as a versatile, bio- inspired tool by which to conduct single-molecule investigations of DNA, and more recently proteins, RNA, methylated DNA and other polymers.
Rogers-Simmonds, Daisy
core   +1 more source