Results 81 to 90 of about 18,216 (235)

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

open access: yesBMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao   +4 more
wiley   +1 more source

Case Report of Acute Kidney Injury in Organophosphorus Poisoning and Potential Association with Oxime Use [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology
Introduction: Organophosphorus poisoning (OP) represents a significant public health issue, particularly in developing countries, due to its extensive availability and high toxicity.
Nourhan Saeed   +2 more
doaj   +1 more source

One-pot asymmetric cyclocarbohydroxylation sequence for the enantioselective synthesis of functionalised cyclopentanes [PDF]

open access: yes, 2010
International audienceA new method has been developed for the enantioselective synthesis of highly functionalised cyclopentanes bearing up to three stereogenic centres with very high stereoselectivity.
Bonne, Damien   +4 more
core   +3 more sources

Ambident Reactivity in the Phenyl + NO Radical Recombination

open access: yesChemistry – A European Journal, EarlyView.
ABSTRACT The recombination reaction of nitric oxide (NO) with radicals via its oxygen atom, rather than the more common nitrogen site, offers an intriguing pathway to the formation of oxynitrenes. The photochemical isomerization of nitroso compounds into their corresponding oxynitrenes may involve such a step.
Virinder Bhagat   +3 more
wiley   +1 more source

Synthesis and 5α-Reductase Inhibitory Activity of C21 Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes

open access: yesMolecules, 2011
The synthesis and evaluation of 5α-reductase inhibitory activity of some 4-azasteroid-20-ones and 20-oximes and 3β-hydroxy-, 3β-acetoxy-, or epoxy-substituted C21 steroidal 20-ones and 20-oximes having double bonds in the A and/or B ring are described ...
Eunsook Ma, Yong-ung Kim, Sujeong Kim
doaj   +1 more source

Organofosforni spojevi i esteraze: stanje sadašnjih istraživanja toksičnosti i zaštite od organofosfata [PDF]

open access: yes, 2001
This brief review describes the reactions of organophosphorus compounds with cholinesterases, neuropathy target esterase, and phosphoric triester hydrolases with respect to their toxicity.
Elsa Reiner
core   +1 more source

Molecular interconversion behaviour in comprehensive two-dimensional gas chromatography [PDF]

open access: yes, 2004
Comprehensive two-dimensional gas chromatography (GC x GC) is shown to provide information on dynamic molecular behaviour (interconversion), with the interconversion process occurring on both columns in the coupled-column experiment.
Aryusuk, K   +6 more
core   +1 more source

Electrochemical Dehydration of Carboxamides to Their Nitriles

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Electrochemical dehydration of carboxamides to nitriles is achieved using thiocyanate‐mediated activation, avoiding stoichiometric reagents. In an undivided cell at ambient conditions, 18 aromatic and aliphatic substrates give good‐to‐excellent yields (up to 84%) with functional‐group tolerance. Cyclic voltammetry supports an EC‐type‐mediated oxidation.
Enrico Lunghi   +2 more
wiley   +1 more source

The Influence of the Time of Antidotal Treatment Administration on the Potency of Newly Developed Oximes to Counteract Acute Toxic Effects of Tabun in Mice

open access: yesActa Medica, 2005
1. The influence of the time of administration of antidotal treatment consisting of anticholinergic drug (atropine) and newly developed oxime (K027 or K048) on its effectiveness to eliminate tabun-induced lethal toxic effects was studied in mice. 2.
Jiří Kassa
doaj   +1 more source

Synthesis of 3,5-Disubstituted Isoxazoles and Isoxazolines in Deep Eutectic Solvents [PDF]

open access: yes, 2015
The synthesis of different 3,5-disubstituted isoxazoles and related isoxazolines using choline chloride:urea as deep eutectic solvent (DES) in a one-pot three step reaction has been accomplished successfully. The use of highly nucleophilic functionalized
Pérez Galera, Juana María   +1 more
core   +3 more sources

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