Results 31 to 40 of about 8,483 (210)
A short and efficient multicomponent sequence for synthesizing fused novel polyheterocyclic chromeno spiro-pyrrolidine oxindoles via 1,3-dipolar cycloaddition reaction mediated by reactive azomethine ylides catalyzed by the Graphene Oxide (GO) is ...
Vipin Singh +2 more
doaj +1 more source
Dichloromethylation of enones by carbon nitride photocatalysis
Small organic radicals are ubiquitous intermediates in photocatalysis and are used in organic synthesis to install functional groups and to tune electronic properties and pharmacokinetic parameters of the final molecule.
Antonietti, M. +4 more
core +1 more source
Synthesis of oxindoles and benozfuranones via oxidation of 2-heterocyclic BMIDAs [PDF]
The synthesis of functionalized oxindoles and benzofuranones via oxidation of 2-BMIDA indoles and benzofurans, respectively, is described. Interconversion of boron species (BMIDAàBF3K) was necessary to enable oxidation and overcome boronic acid stability
Fyfe, James W. B. +3 more
core +1 more source
Photochemical aryl radical cyclizations to give (E)-3-Ylideneoxindoles [PDF]
(E)-3-Ylideneoxindoles are prepared in methanol in reasonable to good yields, as adducts of photochemical 5-exo-trig of aryl radicals, in contrast to previously reported analogous radical cyclizations initiated by tris(trimethylsilyl)silane and azo ...
Aldabbagh, Fawaz +5 more
core +2 more sources
The enantioselective conjugate addition reaction of 3-aryl-substituted oxindoles with methyl vinyl ketone promoted by binaphthyl-modified bifunctional organocatalysts was investigated.
Saet Byeol Woo +2 more
doaj +1 more source
Organocatalytic Lewis base functionalisation of carboxylic acids, esters and anhydrides via C1-ammonium or azolium enolates [PDF]
This tutorial review highlights the organocatalytic Lewis base functionalisation of carboxylic acids, esters and anhydrides via C1-ammonium/azolium enolates.
Morrill, Louis C., Smith, Andrew D.
core +1 more source
An efficient synthesis of functionalized spiropyrrolizidine oxindoles via a three-component tandem cycloaddition has been achieved. This strategy can provide direct and rapid access to spiropyrrolizidine oxindoles in high yields (up to 99%) with ...
Tai-Ran Kang +5 more
doaj +1 more source
Oxindoles and copper complexes with oxindole-derivatives as potential pharmacological agents [PDF]
Oxindoles are endogenous compounds found in mammalian body fluids and tissues. Particularly, isatin (1H-indole-2,3-dione) and its derivatives have shown a variety of biological effects, including inhibition of monoamine oxidase, antibacterial, antifungal, antiviral and antiproliferative activities.
Cerchiaro, Giselle +1 more
openaire +3 more sources
Catalytic Enantioselective Construction of Quaternary Stereocenters: Assembly of Key Building Blocks for the Synthesis of Biologically Active Molecules [PDF]
The ever-present demand for drugs with better efficacy and fewer side effects continually motivates scientists to explore the vast chemical space. Traditionally, medicinal chemists have focused much attention on achiral or so-called “flat” molecules ...
Han, Seo-Jung +3 more
core +1 more source
Alkylidene oxindoles are important functional moieties and building blocks in pharmaceutical and synthetic chemistry. Our interest in biologically active compounds focused our studies on the synthesis of novel oxindoles, bearing on the exocyclic double ...
Boris Letribot +7 more
doaj +1 more source

