Results 11 to 20 of about 4,675 (154)

Questioning the Role of Palmitoylethanolamide in Psychosis: A Systematic Review of Clinical and Preclinical Evidence

, 2023
This review aims at gathering and discussing all available data from clinical and preclinical evidence regarding the role of palmitoylethanolamide (PEA) in psychosis and related conditions by conducting a systematic literature search for all such ...
Riccardo Bortoletto, Marco Colizzi
core   +11 more sources

The effects of formulated palmitoylethanolamide supplementation on indicators of stress and heart rate variability in female university students: a randomised cross-over trial. [PDF]

Front Nutr
BackgroundChronic stress is a prevalent issue among university students, negatively affecting both mental and physiological health. Palmitoylethanolamide (PEA), particularly in the Levagen+® formulation, has been investigated for its potential stress ...
Deb SK, Kim N, Parolin B, Renshaw D, Zariwala MG.   +4 more
europepmc   +2 more sources

Palmitoylethanolamide for Nickel Allergy: Plausible, Untested, and Worth Considering. [PDF]

Biomedicines
Nickel allergy remains the most prevalent cause of allergic contact dermatitis worldwide, imposing a substantial socio-epidemiological and economic burden.
Palenca I, Basili Franzin S, Sarnelli G, Esposito G.   +3 more
europepmc   +2 more sources

Circulating Endocannabinoids in Canine Multicentric Lymphoma Patients

Frontiers in Veterinary Science, 2022
The endocannabinoid system is increasingly being implicated in the pathogenesis and progression of various human cancers. Specifically, increased levels of 2-arachidonoylglycerol (2-AG) and oleoythanolamide (OEA) have been demonstrated in human diffuse ...
Jennifer K. Hay, Samuel E. Hocker, Samuel E. Hocker, Gabrielle Monteith, J. Paul Woods   +4 more
doaj   +1 more source

Micronized Palmitoylethanolamide, Hempseed Oil, and Maritime Pine Bark Dry Extract (Pelvipea^®) for Pelvic Pain: An In Vitro Study for Urothelial Inflammation Treatment

Cells, 2023
Urothelial inflammation plays a key role in the pathogenesis of chronic pelvic pain due to its origin in the bladder. The aim of this study was to evaluate the efficacy of a patent-pending formulation (Pelvipea®) composed of micronized ...
Alessandro Tafuri, Andrea Panunzio, Rita De Mitri, Federico Benetti, Elisa Gaio, Vincenzo Pagliarulo   +5 more
doaj   +1 more source

Palmitoylethanolamide in the Treatment of Pain and Its Clinical Application Prospects [PDF]

Drug Design, Development and Therapy
Yuanming Pan
exaly   +2 more sources

Design, Characterization, and In Vitro Assays on Muscle Cells of Endocannabinoid-like Molecule Loaded Lipid Nanoparticles for a Therapeutic Anti-Inflammatory Approach to Sarcopenia

Pharmaceutics, 2022
Inflammatory processes play a key role in the pathogenesis of sarcopenia owing to their effects on the balance between muscle protein breakdown and synthesis. Palmitoylethanolamide (PEA), an endocannabinoid-like molecule, has been well documented for its
Eleonora Maretti, Susanna Molinari, Renata Battini, Cecilia Rustichelli, Eleonora Truzzi, Valentina Iannuccelli, Eliana Leo   +6 more
doaj   +1 more source

Potential Mechanisms Involved in Palmitoylethanolamide-Induced Vasodepressor Effects in Rats [PDF]

, 2020
Palmitoylethanolamide is an endogenous lipid that exerts complex vascular effects, enhances the effects of endocannabinoids and induces a direct hypotension, but the mechanisms involved have been poorly explored.
González-Hernández, A. (Abimael), Ramírez-San Juan, E. (Eduardo), Maassen van den Brink, A. (Antoinette), Maassen van den Brink, Antoinette, Villalón, C.M. (Carlos), Marichal-Cancino, BA, Gonzalez-Hernandez, A, Marichal-Cancino, B.A. (Bruno), Ramirez-San Juan, E, Villalon, CM   +9 more
core   +1 more source

Effect of Ultra-Micronized Palmitoylethanolamide and Luteolin on Olfaction and Memory in Patients with Long COVID: Results of a Longitudinal Study

Cells, 2022
In this study, we investigated whether treatment with palmitoylethanolamide and luteolin (PEA-LUT) leads to improvement in the quantitative or qualitative measures of olfactory dysfunction or relief from mental clouding in patients affected by long COVID.
Pietro De Luca, Angelo Camaioni, Pasquale Marra, Giovanni Salzano, Giovanni Carriere, Luca Ricciardi, Resi Pucci, Nicola Montemurro, Michael J. Brenner, Arianna Di Stadio   +9 more
doaj   +1 more source

An Update of Palmitoylethanolamide and Luteolin Effects in Preclinical and Clinical Studies of Neuroinflammatory Events

Antioxidants, 2020
The inflammation process represents of a dynamic series of phenomena that manifest themselves with an intense vascular reaction. Neuroinflammation is a reply from the central nervous system (CNS) and the peripheral nervous system (PNS) to a changed ...
Marika Cordaro, Salvatore Cuzzocrea, Rosalia Crupi   +2 more
doaj   +1 more source