Results 31 to 40 of about 1,588 (158)

Protective role of palmitoylethanolamide in contact allergic dermatitis [PDF]

Allergy, 2010
To cite this article:Petrosino S, Cristino L, Karsak M, Gaffal E, Ueda N, Tüting T, Bisogno T, De Filippis D, D’Amico A, Saturnino C, Orlando P, Zimmer A, Iuvone T, Di Marzo V. Protective role of palmitoylethanolamide in contact allergic dermatitis.Allergy2010;65: 698–711.AbstractBackground: Palmitoylethanolamide (PEA) is an anti‐inflammatory mediator ...
Petrosino S, Cristino L, Karsak M, Gaffal E, Ueda N, Tüting T, Bisogno T, De Filippis D, D'Amico A, Saturnino C, Orlando P, Zimmer A, Iuvone T, Di Marzo V   +13 more
openaire   +6 more sources

Endocannabinoids and Human Sperm Cells

Pharmaceuticals, 2010
N-acylethanolamides (NAEs) are naturally occurring signaling lipids consisting of amides and esters of long-chain polyunsaturated fatty acids. Usually they are present in a very small amounts in many mammalian tissues and cells, including human ...
Giovanna Zolese, Annarina Ambrosini, Rosamaria Fiorini   +2 more
doaj   +1 more source

Opposite Effects of Neuroprotective Cannabinoids, Palmitoylethanolamide, and 2-Arachidonoylglycerol on Function and Morphology of Microglia

Frontiers in Neuroscience, 2019
Various studies performed in cultured cells and in in vivo models of neuronal damage showed that cannabinoids exert a neuroprotective effect. The increase in cannabinoids and cannabinoid like substances after stroke has been postulated to limit the ...
Urszula Hohmann, Markus Pelzer, Joshua Kleine, Tim Hohmann, Chalid Ghadban, Faramarz Dehghani   +5 more
doaj   +1 more source

Distribution of Cannabinoid Receptors in Keratinocytes of Healthy Dogs and Dogs With Atopic Dermatitis

Frontiers in Veterinary Science, 2022
It is commonly accepted that some form of skin barrier dysfunction is present in canine atopic dermatitis (AD), one of the most common cutaneous pruritic inflammatory diseases of dogs.
Roberto Chiocchetti, Margherita De Silva, Francesca Aspidi, Rodrigo Zamith Cunha, Francesca Gobbo, Claudio Tagliavia, Giuseppe Sarli, Maria Morini   +7 more
doaj   +1 more source

Palmitoylethanolamide in CNS health and disease

Pharmacological Research, 2014
The existence of acylethanolamides (AEs) in the mammalian brain has been known for decades. Among AEs, palmitoylethanolamide (PEA) is abundant in the central nervous system (CNS) and conspicuously produced by neurons and glial cells. Antihyperalgesic and neuroprotective properties of PEA have been mainly related to the reduction of neuronal firing and ...
MATTACE RASO, GIUSEPPINA, RUSSO, ROBERTO, CALIGNANO, ANTONIO, MELI, ROSARIA   +3 more
openaire   +3 more sources

Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation [PDF]

, 2018
Objective Palmitoylethanolamide is an endogenous fatty acid mediator that is synthetized from membrane phospholipids by N-acyl phosphatidylethanolamine phospholipase D.
Raitoharju, Emma, Guillamat-Prats, Raquel, Vorst, Emiel P. C. van der, Lehtimaki, Terho, Bindila, Laura, Lyytikainen, Leo-Pekka, Rinne, Petteri, van der Vorst, Emiel P. C., Weber, Christian, Rami, Martina, Oksala, Niku, Steffens, Sabine, Ring, Larisa   +12 more
core   +1 more source

Quantification of Analgesic and Anti-Inflammatory Lipid Mediators in Long-Term Cryopreserved and Freeze-Dried Preserved Human Amniotic Membrane

Bioengineering, 2023
The aim of this study was to compare concentrations of endogenous N-acylethanolamine (NAE) lipid mediators—palmitoylethanolamide (PEA), oleoylethanolamide (OEA), and anandamide (AEA)—in fresh, decontaminated, cryopreserved, and freeze-dried amniotic ...
Vladimir Vrkoslav, Ingrida Smeringaiova, Natalia Smorodinova, Alzbeta Svobodova, Stepan Strnad, Catherine Joan Jackson, Jan Burkert, Katerina Jirsova   +7 more
doaj   +1 more source

Anticonvulsant activity of N-palmitoylethanolamide, a putative endocannabinoid, in mice

, 2001
Purpose: The purpose of this study was to evaluate in mice the antieonvulsant potential of N-palmitoylethanolamide, a putative endocannabinoid that accumulates in the body during inflammatory processes.
Vandevoorde, Séverine, Lambert, Didier D.M., Robert, Annie, Diependaele, Gérald, Govaerts, Sophie S.J.   +4 more
core   +2 more sources

Chronic orofacial pain management: A narrative review of pharmacological and promising therapy

Medical Journal of Babylon, 2023
Chronic orofacial pain is a multifactorial stressful condition. It devastates patients’ lives and depletes medical and dental services. Assertion of a particular effective pharmacological treatment is difficult due to psychological involvement and ...
Malath Azeez Al-saadi
doaj   +1 more source

Distribution of an analgesic palmitoylethanolamide and other N-acylethanolamines in human placental membranes.

, 2023
BackgroundHuman amniotic and amniochorionic membranes (AM, ACM) represent the most often used grafts accelerating wound healing. Palmitoylethanolamide, oleoylethanolamide and anandamide are endogenous bioactive lipid molecules, generally referred as N ...
Alzbeta Svobodova, Ingrida Smeringaiova, Katerina Jirsova, Vladimir Vrkoslav   +3 more
core   +1 more source