Results 121 to 130 of about 5,402 (167)

Hyperactivation of SREBP induces pannexin-1-dependent lytic cell death. [PDF]

J Lipid Res
Xiong Y, Luo J, Hong ZY, Zhu WZ, Hu A, Song BL.   +5 more
europepmc   +1 more source

DAMPs prognostic signature predicts tumor immunotherapy, and identifies immunosuppressive mechanism of pannexin 1 channels in pancreatic ductal adenocarcinoma. [PDF]

Front Immunol
Wu Q, Xiao Q, Tang X, Li L, Song D, Zhou Y, Li B, Ren G, Luo F.   +8 more
europepmc   +1 more source

Poly (I:C)-induced inflammation requires the activation of toll-like receptor 3/Ca²⁺/CaMKII/pannexin 1-dependent signaling. [PDF]

Theranostics
Salgado M, Sepúlveda-Arriagada V, Konar-Nié M, García-Robles MA, Sáez JC.   +4 more
europepmc   +1 more source

Pannexin 1 dysregulation in Duchenne muscular dystrophy and its exacerbation of dystrophic features in mdx mice. [PDF]

Skelet Muscle
Freeman E, Langlois S, Leyba MF, Ammar T, Léger Z, McMillan HJ, Renaud JM, Jasmin BJ, Cowan KN.   +8 more
europepmc   +1 more source

Pannexin-1 channel inhibition alleviates opioid withdrawal in rodents by modulating locus coeruleus to spinal cord circuitry. [PDF]

Nat Commun
Kwok CHT, Harding EK, Burma NE, Markovic T, Massaly N, van den Hoogen NJ, Stokes-Heck S, Gambeta E, Komarek K, Yoon HJ, Navis KE, McAllister BB, Canet-Pons J, Fan C, Dalgarno R, Gorobets E, Papatzimas JW, Zhang Z, Kohro Y, Anderson CL, Thompson RJ, Derksen DJ, Morón JA, Zamponi GW, Trang T.   +24 more
europepmc   +1 more source

The ATP-exporting channel Pannexin 1 promotes CD8⁺ T cell effector and memory responses. [PDF]

iScience
Vardam-Kaur T, Banuelos A, Gabaldon-Parish M, Macedo BG, Salgado CL, Wanhainen KM, Zhou MH, van Dijk S, Santiago-Carvalho I, Beniwal AS, Leff CL, Peng C, Tran NL, Jameson SC, Borges da Silva H.   +14 more
europepmc   +1 more source

N-methyl-D-aspartate receptor activation is downstream coupled to pannexin 1 opening by Src kinase in dorsal horn neurons: an essential link for mechanical hyperalgesia in nerve-injured rats. [PDF]

Pain
Zepeda-Morales K, Bravo D, Aránguiz-Barrera J, Ampuero E, Renard GM, Pelissier T, Hernández A, Retamal JS, Constandil L.   +8 more
europepmc   +1 more source

Activation of Pannexin-1 channels causes cell dysfunction and damage in mesangial cells derived from angiotensin II-exposed mice. [PDF]

Front Cell Dev Biol
Lucero CM, Navarro L, Barros-Osorio C, Cáceres-Conejeros P, Orellana JA, Gómez GI.   +5 more
europepmc   +1 more source

Pannexin-1 Channels as Mediators of Neuroinflammation [PDF]

International Journal of Molecular Sciences, 2021
Neuroinflammation is a major component of central nervous system (CNS) injuries and neurological diseases, including Alzheimer’s disease, multiple sclerosis, neuropathic pain, and brain trauma. The activation of innate immune cells at the damage site causes the release of pro-inflammatory cytokines and chemokines, which alter the functionality of ...
Seo, Joon Ho, Dalal, Miloni S, Contreras, Jorge E   +2 more
exaly   +5 more sources