Results 81 to 90 of about 5,402 (167)
HeliyonGlaesserella parasuis can induce endothelial barrier damage in piglets, although the mechanism by which this pathogen triggers inflammatory damage remains unclear. Baicalin possesses anti-inflammatory and anti-oxidant activities.
Shulin Fu +11 more
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The two faces of pannexins: new roles in inflammation and repair
Journal of Inflammation Research, 2018 Helen P Makarenkova,1 Sameer B Shah,2,3 Valery I Shestopalov4–6 1Department of Molecular Medicine, Scripps Research Institute, 2Departments of Orthopaedic Surgery and Bioengineering, University of California, 3Research Division, Veterans Affairs ...
Makarenkova HP, Shah SB, Shestopalov VI
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تأثیر تمرینات HIIT بر تغییرات Pannexin-1،P2X7، NLRP-1 بافت قلب موشهای صحرایی نر نژاد ویستار مبتلا به دیابت نوع 2 [PDF]
مجله دانشکده پزشکی اصفهانمقاله پژوهشیمقدمه: هدف پژوهش حاضر، مطالعهی تأثیر تمرینات HIIT بر تغییرات سطوح پروتئینهای Pannexin-1، P2X7، NLRP-1 بافت قلب موشهای صحرایی نر نژاد ویستار مبتلا به دیابت نوع 2 میباشد.روشها: در این مطالعه، تعداد 40 سر موش صحرایی نر 8 هفتهای از نژاد ...
یاسمن رفیعی +3 more
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The Role of Pannexin-1 Channel- Review
, 2022 Three relations compose the Pannexin family of channel forming glycoproteins such as Pannexin-1 (Panx1, Gen-Bank AAQ89382.1, 426 amino-acids), Pannexin-2 (Panx2, Gen-Bank AAI01024.1, 74.4 kDa) and Pannexin-3 (Panx3, Gen-Bank AAK95655.1, 392 aminoacids, 44.7 kDa). Their primary performance is outlined by their capability to make single membrane channels
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Physiological mechanisms for the modulation of pannexin 1 channel activity
The Journal of Physiology, 2012 Abstract It is widely recognized that ATP, along with other nucleotides, subserves important intercellular signalling processes. Among various nucleotide release mechanisms, the relatively recently identified pannexin 1 (Panx1) channel is gaining prominence by virtue of its ability to support nucleotide permeation and release in a variety of different ...
Joanna K, Sandilos, Douglas A, Bayliss
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Pannexin 1 sustains the electrophysiological responsiveness of retinal ganglion cells
Scientific Reports, 2018 Pannexin 1 (Panx1) forms ATP-permeable membrane channels that play a key role in purinergic signaling in the nervous system in both normal and pathological conditions.
Galina Dvoriantchikova +11 more
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Pannexin 3, but not pannexin 1 is an important pro-catabolic mediator in osteoarthritis. [PDF]
Osteoarthritis and Cartilage, 2016 Moon, P. +3 more
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Source_file.xlsxCryo-EM structures of Pannexin 1 and 3 reveal differences among Pannexin isoforms
Pannexins are single-membrane large-pore ion channels that releases ions and ATP upon activation. Three isoforms of pannexins 1, 2, and 3, perform diverse cellular roles and differ in their pore lining residues. In this study, we report the cryo-EM structure of pannexin 3 at 3.9 Å and analyze its structural differences with pannexin isoforms 1 and 2 ...
Penmatsa, Aravind +2 more
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Commentary: Metabolites released from apoptotic cells act as tissue messengers
Frontiers in Immunology, 2020 Chong Zeng +5 more
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