Results 81 to 90 of about 1,937 (148)

Pannexins in ischemia-induced neurodegeneration

, 2011
Pannexin 1 (Px1, Panx1) and pannexin 2 (Px2, Panx2) form large-pore nonselective channels in the plasma membrane of cells and were suggested to play a role in the pathophysiology of cerebral ischemia.
Ridder, Dirk A., Penuela, Silvia, Herb, Anne, Anne Herb, Monyer, Hannah, Markus Schwaninger, Panagiotis Bargiotas, Antje Krenz, Krenz, Antje, Barakat, Waleed, Jakob von Engelhardt, Silvia Penuela, Waleed Barakat, Hormuzdi, Sheriar G., Bargiotas, Panagiotis, von Engelhardt, Jakob, Sheriar G. Hormuzdi, Hannah Monyer, Schwaninger, Markus, Dirk A. Ridder   +19 more
core   +1 more source

Glial connexins and pannexins in the healthy and diseased brain

, 2021
Over the past several decades a large amount of data have established that glial cells, the main cell population in the brain, dynamically interact with neurons and thus impact their activity and survival.
Naus, Christian C., Sáez, Juan C., Giaume, C., Saez, Juan Carlos, Leybaert, Luc, Giaume, Christian, Naus, C. C., Leybaert, L., Giaume, Christian BA   +8 more
core   +1 more source

The ins and outs of connexins and pannexins beyond the cell surface

Classically implicated in the transport of small molecules between neighboring cells or into the extracellular milieu, emerging evidence implicates connexins and pannexins in other noncanonical biological functions.
Geli, Maria Isabel, Martins-Marques, Tania, Vasconcelos-Cardoso, Maria, Aasen, Trond, Girao, Henrique, Kwak, Brenda   +5 more
core   +1 more source

Roles of connexins and pannexins in (neuro)endocrine physiology [PDF]

, 2015
International audienceTo ensure appropriate secretion in response to organismal demand, (neuro)endocrine tissues liberate massive quantities of hormone, which act to coordinate and synchronize biological signals in distant secretory and non-secretory ...
Hodson, David,, Guérineau, NC, Legros, C, Desarménien, MG, Hodson, David, J, Desarménien, Michel G, Guérineau, Nathalie C, Legros, Christian, Guérineau, Nathalie C., Hodson, DJ, Hodson, David J   +10 more
core   +1 more source

Pannexins are new molecular candidates for assembling gap junctions in the cochlea

, 2008
Genetic studies have linked many nonsyndromic deafness patients to mutations in genes coding for gap junction proteins. To better understand molecular identities of gap junctions in the cochlea, we investigated the expression of pannexins (Panxs ...
Ahmad, Shoeb, Tang, Wenxue, Shestopalov, Valery I, Lin, Xi   +3 more
core   +1 more source

Connexins and pannexins: Coordinating cellular communication in the testis and epididymis

, 2011
Gap junctions and connexins are critical for coordinating cellular functions in complex epithelia. In recent years there has been increased interest in understanding the regulation and function of gap junctions in both the testis and epididymis.
Cyr, Daniel G., Cyr, Daniel G
core   +1 more source

Editorial: Pannexin and connexin signaling in cell death and tissue health and disease. [PDF]

Front Cell Dev Biol, 2023
Mesnil M, Boyce AKJ, Wright CS.
europepmc   +1 more source

Connexins and pannexins in the integumentary system: the skin and appendages:The skin and appendages

, 2015
The integumentary system comprises the skin and its appendages, which includes hair, nails, feathers, sebaceous and eccrine glands. In this review, we focus on the expression profile of connexins and pannexins throughout the integumentary system in ...
Wright, Catherine; id_orcid, Faniku, Chrysovalantou, Martin, Patricia   +2 more
core   +1 more source

Role of pannexins in vasculature [PDF]

, 2017
Pannexins are newly discovered proteins that were first discovered by Panchin in 2000. The pannexin family has three isomers, i.e. pannexin-1, pannexin-2, and pannexin-3.
Habib, Alaa
core  

Pharmacology of pannexin channels. [PDF]

Curr Opin Pharmacol, 2023
Koval M, Schug WJ, Isakson BE.
europepmc   +1 more source