Results 21 to 30 of about 2,313,645 (331)
Food Chemistry: X, 2023 Tartary buckwheat contains more valuable nutrients than common buckwheat, but it also contains allergenic proteins that induce allergic reactions through an IgE-mediated response.
Yiming Zhou +3 more
doaj +1 more source
Isolation of recombinant phage antibodies targeting the hemagglutinin cleavage site of highly pathogenic avian influenza virus. [PDF]
PLoS ONE, 2013 Highly pathogenic avian influenza (HPAI) H5N1 viruses, which have emerged in poultry and other wildlife worldwide, contain a characteristic multi-basic cleavage site (CS) in the hemagglutinin protein (HA).
Jinhua Dong +5 more
doaj +1 more source
The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release. [PDF]
PLoS ONE, 2018 Major Histocompatibility Complex class II (MHC-II) molecules bind peptides and present them to receptors on CD4+ T cells as part of the immune system's surveillance of pathogens and malignancy.
Maria Pia Negroni, Lawrence J Stern
doaj +1 more source
Peptide and peptide-inspired checkpoint inhibitors: Protein fragments to cancer immunotherapy
Medicine in Drug Discovery, 2020 Immune system regained the attention of oncologists and has entered the mainstream for cancer therapy since the discovery of checkpoint antibodies targeting CTLA4 and PD-1 pathways.
Pottayil G. Sasikumar +1 more
doaj +1 more source
Active Transport of Peptides Across the Intact Human Tympanic Membrane. [PDF]
, 2018 We previously identified peptides that are actively transported across the intact tympanic membrane (TM) of rats with infected middle ears. To assess the possibility that this transport would also occur across the human TM, we first developed and ...
Alexander, Thomas +9 more
core +1 more source
Molecular basis for passive immunotherapy of Alzheimer's disease [PDF]
, 2007 Amyloid aggregates of the amyloid-{beta} (A{beta}) peptide are implicated in the pathology of Alzheimer's disease. Anti-A{beta} monoclonal antibodies (mAbs) have been shown to reduce amyloid plaques in vitro and in animal studies.
A. S. Gardberg +39 more
core +3 more sources
From Synthetic Fragments of Endogenous Three-Finger Proteins to Potential Drugs
Frontiers in Pharmacology, 2019 The proteins of the Ly6 family have a three-finger folding as snake venom α-neurotoxins, targeting nicotinic acetylcholine receptors (nAChRs), and some of them, like mammalian secreted Ly6/uPAR protein (SLURP1) and membrane-attached Ly-6/neurotoxin ...
Elena V. Kryukova +11 more
doaj +1 more source
Fibrillisation of hydrophobically modified amyloid peptide fragments in an organic solvent [PDF]
, 2007 The self-assembly of a hydrophobically modified fragment of the amyloid beta(A beta) peptide has been studied in methanol. The peptide FFKLVFF is based on A beta(16-20) extended at the N terminus by two phenylalanine residues.
Castelletto, Valeria +2 more
core +1 more source
Simultaneous and Traceless Ligation of Peptide Fragments on DNA Scaffold.
Biomacromolecules, 2019 Peptide ligation is an indispensable step in the chemical synthesis of target peptides and proteins that are difficult to synthesize at once by a solid-phase synthesis.
Gosuke Hayashi +3 more
semanticscholar +1 more source
Proteomes, 2021 Non-invasive urinary peptide biomarkers are able to detect and predict chronic kidney disease (CKD). Moreover, specific urinary peptides enable discrimination of different CKD etiologies and offer an interesting alternative to invasive kidney biopsy ...
Lorenzo Catanese +6 more
doaj +1 more source