Results 21 to 30 of about 527,000 (340)

Evaluation of the zucker diabetic fatty (ZDF) rat as a model for human disease based on urinary peptidomic profiles [PDF]

, 2012
Representative animal models for diabetes-associated vascular complications are extremely relevant in assessing potential therapeutic drugs. While several rodent models for type 2 diabetes (T2D) are available, their relevance in recapitulating renal and ...
Antonia Vlahou, Ariela Benigni, B Jonsson, Bernd Mayer, C Delles, C Weyer, C Zoja, Carlamaria Zoja, CD Wenger, CL Oltman, CS Fox, D Theodorescu, Ferdinand H. Bahlmann, H Mischak, H Mischak, Harald Mischak, J Drube, J Toblli, JO Deguchi, Joachim Jankowski, Julie Klein, Justyna Siwy, K Voros, Karin Jandeleit-Dahm, M Hashemi, M Haubitz, N Ahmed, N Verzijl, ND Rawlings, P Zurbig, Paul Perco, PJ Talmud, PR Cutillas, R Rouse, Robert Stevens, S Andersen, S Wild, SA Varghese, Sophia Kossida, T Nakagawa, TW Kurtz, Wiliam Mullen, Y Benjamini, Y Igarashi   +43 more
core   +15 more sources

Signature Fragment Ions of Biotinylated Peptides [PDF]

Journal of the American Society for Mass Spectrometry, 2020
The use of biotin or biotin-containing reagents is an essential component of many protein purification and labeling technologies. Owing to its small size and high affinity to the avidin family of proteins, biotin is a versatile molecular handle that permits both enrichment and purity that is not easily achieved by other reagents. Traditionally, the use
Santosh Renuse, Anil K. Madugundu, Jae Hun Jung, Seul Kee Byeon, Hana L. Goldschmidt, Raiha Tahir, David Meyers, Dae In Kim, Jevon Cutler, Kwang Pyo Kim, Xinyan Wu, Richard L. Huganir, Akhilesh Pandey   +12 more
openaire   +3 more sources

Peptide Extracts from Seven Medicinal Plants Discovered to Inhibit Oomycete Phytophthora infestans, a Causative Agent of Potato Late Blight Disease

Plants, 2020
We report the inhibitory effect of peptide extracts obtained from seven medicinal plants against a causative agent of late blight disease Phytophthora infestans.
Eugene A. Rogozhin, Alexey S. Vasilchenko, Anna S. Barashkova, Alexey N. Smirnov, Sergey K. Zavriev, Vladimir P. Demushkin   +5 more
doaj   +1 more source

Spatial Structure and Activity of Synthetic Fragments of Lynx1 and of Nicotinic Receptor Loop C Models

Biomolecules, 2020
Lynx1, membrane-bound protein co-localized with the nicotinic acetylcholine receptors (nAChRs) and regulates their function, is a three-finger protein (TFP) made of three β-structural loops, similarly to snake venom α-neurotoxin TFPs.
Konstantin S. Mineev, Elena V. Kryukova, Igor E. Kasheverov, Natalia S. Egorova, Maxim N. Zhmak, Igor A. Ivanov, Dmitry A. Senko, Alexey V. Feofanov, Anastasia A. Ignatova, Alexander S. Arseniev, Yuri N. Utkin, Victor I. Tsetlin   +11 more
doaj   +1 more source

Hit-to-Lead Short Peptides against Dengue Type 2 Envelope Protein: Computational and Experimental Investigations

Molecules, 2022
Data from the World Health Organisation show that the global incidence of dengue infection has risen drastically, with an estimated 400 million cases of dengue infection occurring annually.
Norburhanuddin Johari Zaidi, Adib Afandi Abdullah, Choon Han Heh, Chun-Hung Lin, Rozana Othman, Abdullah Al Hadi Ahmad Fuaad   +5 more
doaj   +1 more source

Fragmentation of amidinated peptide ions [PDF]

Journal of the American Society for Mass Spectrometry, 2004
The collision-induced dissociation characteristics of amidinated and unmodified tryptic peptides are compared using an ion trap mass spectrometer with both electrospray ionization and matrix-assisted laser/desorption ionization (MALDI). Several fragmentation pathways in a number of tryptic peptides of various precursor charge states are found to be ...
Beardsley, Richard L, Reilly, James P
openaire   +2 more sources

Identification of Immune-Active Peptides in Casein Hydrolysates and Its Transport Mechanism on a Caco-2 Monolayer

Foods, 2023
In this study, we investigated the transport mechanism of immune-active peptide fragments isolated from casein gastrointestinal hydrolysates via a Caco-2 monolayer.
Haiyan Xue, Jingjing Han, Jun Ma, Hongxin Song, Baoyuan He, Xiaofeng Liu, Meixia Yi, Lei Zhang   +7 more
doaj   +1 more source

Study on the reduction of Tartary buckwheat allergenicity during Pediococcus pentosaceus fermentation by HPLC-MS/MS analysis

Food Chemistry: X, 2023
Tartary buckwheat contains more valuable nutrients than common buckwheat, but it also contains allergenic proteins that induce allergic reactions through an IgE-mediated response.
Yiming Zhou, Siyuan Yu, Xuanming She, Xiaoli Zhou   +3 more
doaj   +1 more source

Isolation of recombinant phage antibodies targeting the hemagglutinin cleavage site of highly pathogenic avian influenza virus. [PDF]

PLoS ONE, 2013
Highly pathogenic avian influenza (HPAI) H5N1 viruses, which have emerged in poultry and other wildlife worldwide, contain a characteristic multi-basic cleavage site (CS) in the hemagglutinin protein (HA).
Jinhua Dong, Akira Sakurai, Namiko Nomura, Enoch Y Park, Futoshi Shibasaki, Hiroshi Ueda   +5 more
doaj   +1 more source

Light-Induced Orthogonal Fragmentation of Crosslinked Peptides [PDF]

JACS Au, 2023
Crosslinking mass spectrometry provides pivotal information on the structure and interaction of proteins. MS-cleavable crosslinkers are regarded as a cornerstone for the analysis of complex mixtures. Yet they fragment under similar conditions as peptides, leading to mixed fragmentation spectra of the crosslinker and peptide.
Lars Kolbowski, Adam Belsom, Ana M. Pérez-López, Tony Ly, Juri Rappsilber   +4 more
openaire   +4 more sources