Results 101 to 110 of about 13,212 (232)

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet, Marie Netchitaïlo, Fanny Fabre, Elise Belaidi, Claire Arnaud, Anne‐Laure Borel, Patrick Levy, Jean‐Louis Pépin, Renaud Tamisier   +8 more
wiley   +1 more source

CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization[S]

Journal of Lipid Research, 2015
CGI-58/ABHD5 coactivates adipose triglyceride lipase (ATGL). In adipocytes, CGI-58 binds to perilipin 1A on lipid droplets under basal conditions, preventing interaction with ATGL. Upon activation of protein kinase A (PKA), perilipin 1A is phosphorylated
Anita Sahu-Osen, Gabriela Montero-Moran, Matthias Schittmayer, Katarina Fritz, Anna Dinh, Yu-Fang Chang, Derek McMahon, Andras Boeszoermenyi, Irina Cornaciu, Deanna Russell, Monika Oberer, George M. Carman, Ruth Birner-Gruenberger, Dawn L. Brasaemle   +13 more
doaj   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Turning over new ideas in human skeletal muscle proteostasis: What do we know and where to from here?

Experimental Physiology, EarlyView.
Abstract Understanding the turnover of proteins in tissues gives information as to how external stimuli result in phenotypic change. Nowhere is such phenotypic change more conspicuous than skeletal muscle, which can be effectively remodelled by increased loading, ageing and unloading (disuse), all of which are subject to modification by nutrition and ...
Changhyun Lim, James McKendry, Matthew Lees, Philip J. Atherton, Nicholas A. Burd, Andrew M. Holwerda, Luc J. C. van Loon, Chris McGlory, Cameron J. Mitchell, Kenneth Smith, Daniel J. Wilkinson, Tanner Stokes, Stuart M. Phillips   +12 more
wiley   +1 more source

Homology modeling of perilipin 5 (606.8)

The FASEB Journal, 2014
Lipid storage droplets (LSD) regulate the storage of triacylglycerols and cholesteryl esters in the eukaryotic cell. The Perilipin family is a group of five conserved genes coding for LSD‐binding proteins. At least one perilipin has been found in the coat of all currently known LSD. The goal of the project is to generate a threaded model of perilipin 5
Aboubackrine Sarr, Jennifer Bennett, Zach Niday, John Tansey   +3 more
openaire   +1 more source

High intensity interval and traditional endurance training both increase insulin sensitivity, V̇O2peakand skeletal muscle perilipin 2 and perilipin 5 content in sedentary obese males

, 2014
High intensity interval and traditional endurance training both increase insulin sensitivity, V̇O2peakand skeletal muscle perilipin 2 and perilipin 5 content in sedentary obese ...
T Barker (11056167), S Shepherd (13598530), A Ranasinghe (13658800), Chris Shaw (13067796), AJM Wagenmakers (8476632), A McClean (13658803), M Cocks (8476629)   +6 more
core  

Insertion of perilipin 3 into a glycero(phospho)lipid monolayer depends on lipid headgroup and acyl chain species[S]

Journal of Lipid Research, 2016
Lipid droplets (LDs) are organelles that contribute to various cellular functions that are vital for life. Aside from acting as a neutral lipid storage depot, they are also involved in building new membranes, synthesis of steroid hormones, and cell ...
Mona Mirheydari, Sewwandi S. Rathnayake, Hannah Frederick, Taylor Arhar, Elizabeth K. Mann, Simon Cocklin, Edgar E. Kooijman   +6 more
doaj   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

Analysis of Phosphorylation Sites in Perilipin 5

The FASEB Journal, 2019
In modern times, there has been a significant increase in metabolic disease. Obesity has been a growing concern in the U.S, leading to a rise in various health problems, such as type II diabetes and cardiovascular disease. One major factor in these diseases is lipid metabolism.
Natalie M Sumser, John T Tansey
openaire   +1 more source

Effects of bed rest and immobilization on intramuscular and intermuscular adipose tissue: A systematic review

Experimental Physiology, EarlyView.
Abstract Muscle disuse caused by bed rest and immobilization is associated with muscle atrophy and insulin resistance, which might be related to increases in intramuscular fat (IntraMAT) and intermuscular fat (InterMAT) accumulation. In this systematic review, we compiled evidence on the effects of bed rest and unilateral lower‐limb immobilization on ...
Konstantinos Prokopidis, Julia Margarita Reyes, Gustavo Duque   +2 more
wiley   +1 more source