Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Aim: To investigate the mediating role of person-organization fit in the effect of perceived organizational support in nurses on job stress. Method: The sample of the study consisted of 500 nurses working at a university hospital in Eskişehir (N = 923 ...
Merve Özlü, Aysun Türe
doaj +1 more source
Work-life balance practices and organizational cynicism: The mediating role of person-job fit. [PDF]
Kakar AS +4 more
europepmc +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
The Relationship Between Job Autonomy and Work-Leisure Conflict: Based on the Person-Job Fit Perspective. [PDF]
Wang F, Zhang Z, Shi W.
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
The Influence of Person-Job Fit on Health Status and Depression Among Chinese Domestic Workers: Mediating Effect of the Employer-Employee Relationship. [PDF]
Chen L, Jilili M, Wang R, Liu L, Yang A.
europepmc +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Career adaptability and work engagement: the roles of person–organization fit and job insecurity
Purpose The purpose of this study is to examine the relationship between employees’ career adaptability and work engagement. Specifically, this study investigates the mediating role of person‒organization fit in the relationship between career ...
Qishan Chen +5 more
doaj +1 more source
The Impact of Career Adaptability on Career Plateau: The Mediating Role of Person-Job Fit and Person-Organization Fit [PDF]
This research has been conducted to examine the impact of career adaptability on career plateau by explaining the mediating role of person-job fit and person-organization fit. In terms of purpose, the study is applied and it was conducted by descriptive /
Hojjat Taheri Goodarzi, Neda Norouzi
doaj

