Results 141 to 150 of about 4,671,311 (277)

Associations between person-environment fit and mental health - results from the population-based LIFE-Adult-Study

open access: yesBMC Public Health
Within occupational settings, mental health of employees can be affected by complex interactions between individuals and their work environment. The aim of this cross-sectional analysis was to investigate the association between person-environment fit ...
Franziska U. Jung   +13 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Analisis Pengaruh Person-Organization Fit dan Person-Job fit terhadap Kinerja Karyawan [PDF]

open access: yes
Person-Organization fit has provided a deep understanding of increasing the fit between employees and the organization, retaining employees in the long term by increasing employee satisfaction and commitment to the company, as well as improving ...
Niken Permata Sari   +2 more
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

The contribution of person organization fit to employee engagement [PDF]

open access: yes, 2013
The main purpose of our research is to investigate the relationship between person-organization value fit and employee engagement. We predict that, independent variable ``person-organization fit?? has a contribution on dependent variable ``employee engagement??.
openaire   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

The relationship between perceived sufficiency of HRM practices, person-organization fit, person-job fit and anxiety

open access: yes, 2009
nsan Kaynakları Uygulamalarının Algılanan Yeterliliği, Kişi-Kurum Uyumu, Kişi-İş Uyumu, Kaygı ÖZET İNSAN KAYNAKLARI UYGULAMALARININ ALGILANAN YETERLİLİĞİ, KİŞİ-KURUM UYUMU, KİŞİ-İŞ UYUMU VE KAYGI ARASINDAKİ İLİŞKİLER Bu araştırmanın temel hedefi, İnsan ...
Yaşar, Neslihan
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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