Results 141 to 150 of about 96,685 (285)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Associations between person-environment fit and mental health - results from the population-based LIFE-Adult-Study

open access: yesBMC Public Health
Within occupational settings, mental health of employees can be affected by complex interactions between individuals and their work environment. The aim of this cross-sectional analysis was to investigate the association between person-environment fit ...
Franziska U. Jung   +13 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Investigating the Portrayal of Organizational Culture in Internet Recruitment: Can Applicants Gain a Sense of Person-Organization Fit through a Recruitment Website?

open access: yes, 2006
This study found that culture-specific pictures on a recruitment website allowed individuals to more accurately assess an organization's culture, while employee testimonials had no such effect.
Kroustalis, Christina Marie
core  

Person-job fit, person-organization fit, proactive personality and career success: The mediating role of job performance [PDF]

open access: yes, 2012
This study examines three factors namely person job fit, person-organization fit and proactive personality that might influence career success. Job performance is also tested as mediator in the relationship between person-job fit, person-organization fit,
Tan, Fee Yean   +5 more
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Person-organization and person-supervisor Fits: Employee commitments in a Chinese context

open access: yes, 2012
[[abstract]]The present study simultaneously examined people's perceptions of person–organization (PO) and person–supervisor (PS) fit and related these perceptions to employees' commitments.
Vianen, van ; A. E. M. ; Shen, Chi-Tai; Chuang, A.
core  

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