Results 31 to 40 of about 3,877 (197)

Horseshoe kidney with PLA2R-positive membranous nephropathy [PDF]

BMC Nephrology, 2021
Abstract Background Horseshoe kidney (HSK) is a common congenital defect of the urinary system. The most common complications are urinary tract infection, urinary stones, and hydronephrosis. HSK can be combined with glomerular diseases, but the diagnosis rate of renal biopsy is low due to structural abnormalities.
Shuai-Shuai Shi, Xian-Zu Yang, Xiao-Ye Zhang, Hui-Dan Guo, Wen-Feng Wang, Li Zhang, Peng Wu, Wei Zhang, Wen-Bin Wen, Xiao-Lei Huo, Yi-Qiang Zhang   +10 more
openaire   +3 more sources

Renal Phospholipase A2 Receptor and the Clinical Features of Idiopathic Membranous Nephropathy

Chinese Medical Journal, 2017
Background: According to the renal phospholipase A2 receptor (PLA2R) immunohistochemistry, idiopathic membranous nephropathy (iMN) could be categorized into PLA2R-associated and non-PLA2R-associated iMN. This study aimed to examine whether the non-PLA2R-
Ning-Xin Xu, Qiong-Hong Xie, Zhu-Xing Sun, Jia Wang, Yan Li, Liang Wang, Shao-Jun Liu, Jun Xue, Chuan-Ming Hao   +8 more
doaj   +1 more source

Determination of Anti-Phospholipase A2 and Anti-Thrombospondin Type 1 Domain-Containing Protein 7A in Latin Patients with Membranous Nephropathy

Diagnostics, 2022
Primary membranous nephropathy (MN) is caused by antibodies against podocyte antigens, especially the type M receptor of phospholipase A2 (PLA2R) and thrombospondin type-1 domain containing 7 A (THSD7A).
Ligia C. Battaini, Otavio T. Ranzani, Lia J. Marçal, Leila Antonangelo, Lecticia B. Jorge, Cristiane D. Bitencourt, Victoria Woronik, Denise M. A. Malheiros, Luis Yu   +8 more
doaj   +1 more source

Animal models of idiopathic membranous nephropathy: Recent advances and future perspectives. [PDF]

Animal Model Exp Med
This review focuses on the evolution of idiopathic membranous nephropathy (IMN) animal models from traditional approaches (Heymann nephritis, C‐BSA, APA) to antigen‐specific models (PLA2R, THSD7A), critically evaluating their advances and limitations in replicating human IMN pathology.
Liu Q, Bian H, Liu J, Wu L, Zhang Z, Zhao H, Qin X.   +6 more
europepmc   +2 more sources

Response to immunosuppressive therapy in PLA2R- associated and non-PLA2R- associated idiopathic membranous nephropathy: a retrospective, multicenter cohort study

BMC Nephrology, 2017
Background According to renal M type phospholipase A2 receptor (PLA2R) immunohistochemistry, idiopathic membranous nephropathy (IMN) could be categorized into PLA2R-associated and non-PLA2R-associated IMN. We conducted a retrospective, multicenter cohort
Jia Wang, Qionghong Xie, Zhuxing Sun, Ningxin Xu, Yan Li, Liang Wang, Shaojun Liu, Jun Xue, Chuan-Ming Hao   +8 more
doaj   +1 more source

Profile of Indian Patients With Membranous Nephropathy

Kidney International Reports, 2020
Introduction: The majority of primary membranous nephropathy (MN) cases are no longer considered idiopathic with the discovery of the podocytic autoantigens: phospholipase A2 receptor (PLA2R) and thrombospondin type 1 domain–containing 7A (THSD7A ...
Priyadarsani Subramanian, Hemanth Kumar, Bipin Tiwari, Adarsh Barwad, Soumita Bagchi, Arvind Bagga, Sanjay Kumar Agarwal, Amit Kumar Dinda, Geetika Singh   +8 more
doaj   +1 more source

Utilidad de los anticuerpos contra el receptor de la fosfolipasa A2 en el diagnóstico y seguimiento de la nefropatía membranosa en Uruguay

Nefrología Latinoamericana, 2021
Antecedentes: En fecha reciente se propuso utilizar el ac-PLA2R en el diagnóstico y seguimiento de la nefropatía membranosa idiopática (NMI). Objetivo: Evaluar el rendimiento de los ac-PLA2R durante el inicio, la remisión y la recaída en los primeros ...
Sofía San Román, Ricardo Silvariño, José Boggia, Cecilia Baccino, Óscar Noboa   +4 more
doaj   +1 more source

The Sensitivity and Specificity of Serum Phospholipase A2 Receptor Antibodies in Diagnosing Primary Membranous Nephropathy in Patients with Adult Nephrotic Syndrome and its Correlation with Serum Phospholipase A2 Receptor Staining in Kidney Biopsies

Saudi Journal of Kidney Diseases and Transplantation, 2023
Membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome (NS) in nondiabetic adults, with about 70%–80% of cases of MN being primary MN (pMN). Many studies have shown that serum phospholipase A2 receptor (PLA2R) antibodies are a
Deepesh Vellakampadi, Ravishankar Bonu, Vishwanath Siddini, Mahesh Vankalakunti   +3 more
doaj   +1 more source

Posttransplant membranous nephropathy - A case report

Indian Journal of Transplantation, 2022
Primary membranous nephropathy (PMN) is a common cause of adult-onset nephrotic syndrome. Anti-M-type phospholipase A2 receptor (PLA2R) antibodies are pathogenic and correlate with clinical outcomes. The role of anti-PLA2R in recurrent PMN is unclear. In
Shabna Sullaiman, Prabhat Chauhan, Ashwani Kumar, Ritambhra Nada, Ranjana Minz, Vinod Kumar, Ashish Sharma, Sarbpreet Singh, Vivek Kumar, Manish Rathi, Harbir Singh Kohli, Raja Ramachandran   +11 more
doaj   +1 more source

Anti-PLA2R antibody in primary and secondary forms of membranous glomerulopathy [PDF]

, 2023
INTRODUÇÃO: A glomerulopatia membranosa (GNM) é considerada a principal causa de síndrome nefrótica em adultos. A maioria dos casos é considerada primária, mas cerca de 20-30% das GNM são secundárias a uma condição clínica subjacente, como neoplasias ...
Gazeta, Cristina do Amaral [UNIFESP]
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