Results 31 to 40 of about 2,806 (128)
Acta Clinica Croatica, 2021 Introduction: primary membranous nephropathy (pMN) is glomerulopathy caused in the majority of cases by autoantibodies to Phospholipase-A2 receptors (PLA2R-AB).
Mario Laganović +15 more
doaj +1 more source
Immunological Medicine, 2020 Associations between anti-M-type phospholipase A2 receptor (PLA2R) antibodies and disease activity and prognosis have been suggested in primary membranous nephropathy (MN); however, more evidence is needed.
Yasuhiro Katsumata +8 more
doaj +1 more source
AGING MEDICINE, EarlyView.This 20‐year retrospective study reveals a significant increase in renal biopsy utilization and a pivotal shift in biopsy‐proven renal disease among Chinese elderly patients. Secondary glomerular nephropathy (particularly diabetic nephropathy and hypertensive nephropathy) has surpassed primary glomerular nephropathy as the leading biopsy‐proven ...
Shasha Han +4 more
wiley +1 more source
PLoS ONE, 2016 The phospholipase A2 receptor (PLA2R) is the major target antigen (Ag) in idiopathic membranous nephropathy (IMN). Recently, several types of immunoassay systems for anti-PLA2R antibody (Ab) have been developed.
Kei Hihara +9 more
doaj +1 more source
Saudi Journal of Kidney Diseases and Transplantation, 2018 Distinguishing primary from secondary forms of membranous nephropathy (MN) in paraffin-embedded kidney biopsies is challenging. Previous studies have measured the accuracy, sensitivity, and specificity of phospholipase A2 receptor (PLA2R) on MN. However,
Nasar Yousuf Alwahaibi +2 more
doaj +1 more source
Presence of M-type Phospholipase A2 Receptor Antibody in Membranous Nephropathy
Turkish Journal of Nephrology, 2020 Objective: The presence of autoantibodies against M-type phospholipase A2 receptor (anti-PLA2R) is a characteristic of idiopathic membranous nephropathy (IMN).
Özgür Akın Oto +7 more
doaj +1 more source
Anti-phospholipase A2 receptor antibodies directly induced podocyte damage in vitro
Renal Failure, 2022 Background The pathogenesis of primary membranous nephropathy (MN) involves the antibodies against antigens on the cell surface of podocytes, with the majority of M-type phospholipase A2 receptor (PLA2R), and a profound podocyte dysfunction.
Yanfen Li +4 more
doaj +1 more source
A membranous nephropathy variant mimicking minimal change disease
The Journal of Pathology: Clinical Research, Volume 12, Issue 1, January 2026.Abstract This study characterizes a novel disease pattern of membranous nephropathy (MN) that exhibits overlapping clinicopathological features with minimal change disease (MCD), termed ‘MCD‐like MN’. Patients with histologically confirmed MN showing sparse and segmental subepithelial electron‐dense deposits (EDD) but clinically resembling MCD were ...
Chuqi Pan +8 more
wiley +1 more source
An anti-phospholipase A2 receptor quantitative immunoassay and epitope analysis in membranous nephropathy reveals different antigenic domains of the receptor. [PDF]
PLoS ONE, 2013 The phospholipase A2 receptor (PLA2R) was recently discovered as a target autoantigen in patients with idiopathic membranous nephropathy (IMN). Published evidence suggests that the autoantibodies directed towards a conformation dependent epitope are ...
Astrid Behnert +8 more
doaj +1 more source
Renal Failure, 2022 Objectives Idiopathic membranous nephropathy (iMN) is a major cause of nephrotic syndrome. Atypical membranous nephropathy (aMN) is a new type of nephropathy in China, characterized by a ‘full-house’ on immunofluorescent examination, that is IgG, IgA ...
Yuchao Zhao +6 more
doaj +1 more source