Results 21 to 30 of about 111,548 (274)
Speeding to Pluripotency [PDF]
Cell, 2014 Finding a cell that reprograms in a nonstochastic manner without genetic manipulation has proven elusive. In this issue, Guo et al. report the identification of a cell defined by an ultrafast cycle whose progeny reprogram in a synchronous and rapid manner.
Chenoweth, Josh G., McKay, Ronald D.
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Differential Expression Pattern of linc-ROR Spliced Variants in Pluripotent and Non-Pluripotent Cell Lines [PDF]
Cell Journal, 2022 Objective: The human large intergenic non-coding RNA-regulator of reprogramming program (linc-ROR) is known as astem cell specific linc-RNA. linc-ROR counteracts differentiation via sequestering microRNA-145 (miR-145) that targets OCT4 transcript ...
Fatemeh Mirzadeh Azad +8 more
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Cell Reports, 2020 Summary: Human naive pluripotent stem cells established from the epiblasts of preimplantation blastocysts provide a useful model for mechanistic studies of pluripotency regulation and lineage differentiation. Important advances have been made to optimize
Yan Bi +10 more
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Proteomics and pluripotency [PDF]
Critical Reviews in Biochemistry and Molecular Biology, 2011 The fields of mass spectrometry (MS) and stem cell biology have expanded greatly in the past twenty years. Taken alone, these fields occupy entirely different branches of science; however, the points where they overlap provide valuable insight, both in the biological and technical arenas.
Justin, Brumbaugh +4 more
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Pressure-induced changes on the morphology and gene expression in mammalian cells
Biology Open, 2021 We evaluated the effect of high hydrostatic pressure on mouse embryonic fibroblasts (MEFs) and mouse embryonic stem (ES) cells. Hydrostatic pressures of 15, 30, 60, and 90 MPa were applied for 10 min, and changes in gene expression were evaluated.
Kazuko Okamoto +5 more
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Cell Research, 2013 Recent studies have uncovered a specific role of TET proteins in reprogramming somatic cells to induced pluripotent stem cells, a process where O-linked β-N-acetylglucosamine transferase may play a crucial role.
Ping, Wang +5 more
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Frontiers in Cell and Developmental Biology, 2023 Characterization of cancer cells and neural stem cells indicates that tumorigenicity and pluripotency are coupled cell properties determined by neural stemness, and tumorigenesis represents a process of progressive loss of original cell identity and gain
Ying Cao, Ying Cao, Ying Cao
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NaNog: A pluripotency homeobox (master) molecule. [PDF]
, 2015 One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed necessary , then at a specified time can differentiate into any type of cell. This fundamental process
Aguib, YE +4 more
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Stem Cell Research, 2017 Loss-of-function mutations in the PITX2 transcription factor gene have been shown to cause familial atrial fibrillation (AF). To potentially model aspects of AF and unravel PITX2-regulated downstream genes for drug target discovery, we here report the ...
Maike Marczenke +5 more
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Frontiers in Psychiatry, 2021 Most psychiatric disorders develop during adolescence and young adulthood and are preceded by a phase during which attenuated or episodic symptoms and functional decline are apparent. The introduction of the ultra-high risk (UHR) criteria two decades ago
Jessica A. Hartmann +21 more
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