Results 61 to 70 of about 2,442 (188)
Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel Activity. [PDF]
PLoS ONE, 2015 Magnesium (Mg2+) is essential for enzymatic activity, brain function and muscle contraction. Blood Mg2+ concentrations are tightly regulated between 0.7 and 1.1 mM by Mg2+ (re)absorption in kidney and intestine.
Maxime G Blanchard +8 more
doaj +1 more source
Frontiers in Plant Science, 2021 Despite its central role as the ark of genetic information and gene expression the plant nucleus is surprisingly understudied. We isolated nuclei from the Arabidopsis thaliana dark grown cell culture left untreated and treated with flg22 and nlp20, two ...
Mohamed Ayash +6 more
doaj +1 more source
Structural and functional comparisons of retroviral envelope protein C-terminal domains: Still much to learn [PDF]
, 2014 Retroviruses are a family of viruses that cause a broad range of pathologies in animals and humans, from the apparently harmless, long-term genomic insertion of endogenous retroviruses, to tumors induced by the oncogenic retroviruses and acquired ...
Kuhlmann, AS +2 more
core +2 more sources
Renal Failure, 2013 Prohibitin (PHB), a ubiquitous protein, plays a number of different molecular functions, and it is mainly located on the inner mitochondrial membrane and nuclei.
Tian-Biao, Zhou, Yuan-Han, Qin
openaire +2 more sources
Prohibitin 1 in liver injury and cancer
Experimental Biology and Medicine, 2020 Prohibitin 1 is an evolutionary conserved and ubiquitously expressed protein that exerts different biological functions depending on its subcellular localization. The role of prohibitin 1 in liver cancer is controversial as it can be pro- or anti-tumorigenic.
Lucía Barbier-Torres, Shelly C Lu
openaire +5 more sources
Structure-function analysis of human stomatin: A mutation study. [PDF]
PLoS ONE, 2017 Stomatin is an ancient, widely expressed, oligomeric, monotopic membrane protein that is associated with cholesterol-rich membranes/lipid rafts. It is part of the SPFH superfamily including stomatin-like proteins, prohibitins, flotillin/reggie proteins ...
Stefanie Rungaldier +5 more
doaj +1 more source
Characterization and functional analysis of the proteins Prohibitin 1 and 2 in Trypanosoma cruzi.
PLoS Neglected Tropical Diseases, 2021 BackgroundChagas disease is the third most important neglected tropical disease. There is no vaccine available, and only two drugs are generally prescribed for the treatment, both of which with a wide range of side effects. Our study of T.
Ana K Ibarrola-Vannucci +8 more
doaj +1 more source
The arabidopsis COX11 homolog is essential for cytochrome c oxidase activity [PDF]
, 2015 Members of the ubiquitous COX11 (cytochrome c oxidase 11) protein family are involved in copper delivery to the COX complex. In this work, we characterize the Arabidopsis thaliana COX11 homolog (encoded by locus At1g02410).
Mansilla, Natanael +3 more
core +6 more sources
Advanced Science, EarlyView.Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu +7 more
wiley +1 more source
A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. [PDF]
, 2011 To broadly explore mitochondrial structure and function as well as the communication of mitochondria with other cellular pathways, we constructed a quantitative, high-density genetic interaction map (the MITO-MAP) in Saccharomyces cerevisiae.
Cassidy-Stone, Ann +9 more
core +2 more sources