Results 11 to 20 of about 6,532,398 (348)

Protein translocation across mitochondrial membranes [PDF]

BioEssays, 1992
Protein translocation across biological membranes is of fundamental importance for the biogenesis of organelles and in protein secretion. We will give an overview of the recent achievements in the understanding of protein translocation across ...
Arretz, Attardi, Baker, Becker, Behrens, Chen, Cheng, Chirico, Deshaies, Drygas, Dumont, Dumont, Eilers, Ellis, Hartl, Hartl, Hartl, Hawlitschek, Hines, Kang, Kellems, Kiebler, Koll, Kusakawa, Mahlke, Murakami, Murakami, Murakami, Neupert, Nicholson, Ono, Ostermann, Ostermann, Ou, Pain, Pelham, Pfaller, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Pollock, Pon, Rassow, Rassow, Reading, Rietveld, Rothman, Scherer, Schleyer, Schneider, Schulte, Schwaiger, Steger, Stuart, Söllner, Söllner, Söllner, Vestweber, Vestweber, Wienhues, Witte   +62 more
core   +4 more sources

EGFR Protein Translocation [PDF]

Definitions, 2020

semanticscholar   +2 more sources

The Rich Tapestry of Bacterial Protein Translocation Systems. [PDF]

Protein J, 2019
Christie PJ.
europepmc   +2 more sources

Signal Peptide Features Determining the Substrate Specificities of Targeting and Translocation Components in Human ER Protein Import

Frontiers in Physiology, 2022
In human cells, approximately 30% of all polypeptides enter the secretory pathway at the level of the endoplasmic reticulum (ER). This process involves cleavable amino-terminal signal peptides (SPs) or more or less amino-terminal transmembrane helices ...
Sven Lang, Duy Nguyen, Pratiti Bhadra, Martin Jung, Volkhard Helms, Richard Zimmermann   +5 more
doaj   +1 more source

The Translocator Protein [PDF]

Journal of Nuclear Medicine, 2011
The translocator protein (TSPO) is expressed at low levels in the healthy human brain and is markedly upregulated in response to brain injury and inflammation. This increase in TSPO expression is correlated to the extent of microglial activation, making the measurement of TSPO density a useful indicator of active brain disease.
Alana M, Scarf, Michael, Kassiou
openaire   +2 more sources

Crosstalk between the chloroplast protein import and SUMO systems revealed through genetic and molecular investigation in Arabidopsis

eLife, 2021
The chloroplast proteome contains thousands of different proteins that are encoded by the nuclear genome. These proteins are imported into the chloroplast via the action of the TOC translocase and associated downstream systems.
Samuel James Watson, Na Li, Yiting Ye, Feijie Wu, Qihua Ling, R Paul Jarvis   +5 more
doaj   +1 more source

Reconstitution of surface lipoprotein translocation through the Slam translocon

eLife, 2022
Surface lipoproteins (SLPs) are peripherally attached to the outer leaflet of the outer membrane in many Gram-negative bacteria, playing significant roles in nutrient acquisition and immune evasion in the host.
Minh Sang Huynh, Yogesh Hooda, Yuzi Raina Li, Maciej Jagielnicki, Christine Chieh-Lin Lai, Trevor F Moraes   +5 more
doaj   +1 more source

Structural overview of the translocase of the mitochondrial outer membrane complex

Biophysics and Physicobiology, 2022
Most mitochondrial proteins are synthesized as precursor proteins (preproteins) in the cytosol and imported into mitochondria. The translocator of the outer membrane (TOM) complex functions as a main entry gate for the import of mitochondrial proteins ...
Yuhei Araiso, Toshiya Endo
doaj   +1 more source

Coordinated Translocation of Presequence-Containing Precursor Proteins Across Two Mitochondrial Membranes: Knowns and Unknowns of How TOM and TIM23 Complexes Cooperate With Each Other

Frontiers in Physiology, 2022
The vast majority of mitochondrial proteins are encoded in the nuclear genome and synthesized on cytosolic ribosomes as precursor proteins with specific mitochondrial targeting signals. Mitochondrial targeting signals are very diverse, however, about 70%
Marcel G. Genge, Dejana Mokranjac
doaj   +1 more source

Protein Translocation: Tunnel Vision [PDF]

Cell, 1998
We apologize to colleagues whose important work could only be covered by reference to reviews and discussions in other papers. We thank M. Rolls, C. Shamu, W. Prinz, and P. Silver for valuable comments on the manuscript. After completion of this manuscript we became aware of a recent review by R. S. Hegde and V. R. Lingappa (Cell 91, 575–582), to which
Matlack, Kent E.S, Mothes, Walther, Rapoport, Tom A   +2 more
openaire   +2 more sources