Results 21 to 30 of about 3,931,468 (303)

Reconstitution of surface lipoprotein translocation through the Slam translocon

eLife, 2022
Surface lipoproteins (SLPs) are peripherally attached to the outer leaflet of the outer membrane in many Gram-negative bacteria, playing significant roles in nutrient acquisition and immune evasion in the host.
Minh Sang Huynh, Yogesh Hooda, Yuzi Raina Li, Maciej Jagielnicki, Christine Chieh-Lin Lai, Trevor F Moraes   +5 more
doaj   +1 more source

Life After Secretion—Yersinia enterocolitica Rapidly Toggles Effector Secretion and Can Resume Cell Division in Response to Changing External Conditions

Frontiers in Microbiology, 2019
Many pathogenic bacteria use the type III secretion system (T3SS) injectisome to manipulate host cells by injecting virulence-promoting effector proteins into the host cytosol.
Bailey Milne-Davies, Carlos Helbig, Stephan Wimmi, Dorothy W. C. Cheng, Nicole Paczia, Andreas Diepold   +5 more
doaj   +1 more source

Structural overview of the translocase of the mitochondrial outer membrane complex

Biophysics and Physicobiology, 2022
Most mitochondrial proteins are synthesized as precursor proteins (preproteins) in the cytosol and imported into mitochondria. The translocator of the outer membrane (TOM) complex functions as a main entry gate for the import of mitochondrial proteins ...
Yuhei Araiso, Toshiya Endo
doaj   +1 more source

Peroxisomal protein translocation

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2010
Peroxisomes perform a wide variety of metabolic processes in eukaryotic organisms. Mutations that affect peroxisome function or formation have profound phenotypic consequences, the latter demonstrated by peroxisome biogenesis disorders which are often fatal.
Girzalsky, Wolfgang, Saffian, Delia, Erdmann, Ralf   +2 more
openaire   +2 more sources

Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complex [PDF]

, 2012
The bacterial ATPase SecA and protein channel complex SecYEG form the core of an essential protein translocation machinery. The nature of the conformational changes induced by each stage of the hydrolytic cycle of ATP and how they are coupled to protein ...
Allen, William J, Collinson, I, Ian Collinson, Allen, WJ, Vicki A.M. Gold, Alice Robson, Gold, VAM, Whitehouse, Sarah, Gold, Vicki A M, Robson, Alice, Whitehouse, S, Collinson, Ian, Robson, A, William J. Allen, Sessions, RB, Sarah Whitehouse, Sessions, Richard B, Richard B. Sessions   +17 more
core   +1 more source

The Roles of Endo-Lysosomes in Unconventional Protein Secretion

Cells, 2018
Protein secretion in general depends on signal sequence (also named leader sequence), a hydrophobic segment located at or close to the NH2-terminus of a secretory or membrane protein.
Juhyung Lee, Yihong Ye
doaj   +1 more source

The protein translocation systems in plants - composition and variability on the example of Solanum lycopersicum [PDF]

, 2013
Background: Protein translocation across membranes is a central process in all cells. In the past decades the molecular composition of the translocation systems in the membranes of the endoplasmic reticulum, peroxisomes, mitochondria and chloroplasts ...
Fragkostefanakis, Sotirios, Simm, Stefan, Mirus, Oliver, Stefan Simm, Klaus-Dieter Scharf, Puneet Paul, Andreas Blaumeiser, Blaumeiser, Andreas, Enrico Schleiff, Sotirios Fragkostefanakis, Schleiff, Enrico, Oliver Mirus, Paul, Puneet, Scharf, Klaus-Dieter   +13 more
core   +1 more source

Coordinated Translocation of Presequence-Containing Precursor Proteins Across Two Mitochondrial Membranes: Knowns and Unknowns of How TOM and TIM23 Complexes Cooperate With Each Other

Frontiers in Physiology, 2022
The vast majority of mitochondrial proteins are encoded in the nuclear genome and synthesized on cytosolic ribosomes as precursor proteins with specific mitochondrial targeting signals. Mitochondrial targeting signals are very diverse, however, about 70%
Marcel G. Genge, Dejana Mokranjac
doaj   +1 more source

The invariant phenylalanine of precursor proteins discloses the importance of Omp85 for protein translocation into cyanelles [PDF]

, 2007
Background Today it is widely accepted that plastids are of cyanobacterial origin. During their evolutionary integration into the metabolic and regulatory networks of the host cell the engulfed cyanobacteria lost their independency.
Schleiff Enrico, Roman Martin, Martin, Roman, Schleiff, Enrico (Ludwig-Maximilians-Universität München (LMU)), Steiner Jürgen M, Steiner, Jürgen M., Loeffelhardt, Wolfgang, Wunder, Tobias (Ludwig-Maximilians-Universität München (LMU)), Löffelhardt Wolfgang, Steiner, Juergen M., Wunder Tobias, Martin, Roman (Ludwig-Maximilians-Universität München (LMU)), Tobias Wunder, Enrico Schleiff, Jürgen M Steiner, Martin Roman, Wunder, Tobias, Löffelhardt, Wolfgang (Department of Biochemistry and Cell Biology, Centre for Molecular Biology, University of Vienna), Schleiff, Enrico, Löffelhardt, Wolfgang, Steiner, Juergen-Michael (Department of Biochemistry and Cell Biology, Centre for Molecular Biology, University of Vienna), Wolfgang Löffelhardt   +21 more
core   +1 more source

The Tat-dependent protein translocation pathway

Biomolecular Concepts, 2011
The twin-arginine translocation (Tat) pathway is found in bacteria, archaea, and plant chloroplasts, where it is dedicated to the transmembrane transport of fully folded proteins.
Hou Bo, Brüser Thomas
doaj   +1 more source