Activation of Serine One-Carbon Metabolism by Calcineurin A beta 1 Reduces Myocardial Hypertrophy and Improves Ventricular Function [PDF]
Background In response to pressure overload, the heart develops ventricular hypertrophy that progressively decompensates and leads to heart failure.
Acin-Perez, R +12 more
core +1 more source
On the relation between azeotropic behavior and minimum / maximum flash point occurrences in binary mixtures of flammable compounds [PDF]
The flash point temperature and the boiling temperature of a mixture are related by the fact that both can be modeled based on vapor-liquid equilibrium (VLE) of each component. It has been suggested in the literature that there might exist a concomitance
Da Cunha, Sergio +2 more
core +3 more sources
Ferritin heavy chain Is the host factor responsible for HCV-Induced inhibition of apoB-100 production and is required for efficient viral infection [PDF]
Hepatic fat export occurs by apolipoprotein B-100-containing lipoprotein production, whereas impaired production leads to liver steatosis. Hepatitis C virus (HCV) infection is associated to dysregulation of apoB-100 secretion and steatosis; however, the ...
AMICONE, Laura +9 more
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A photo-responsive F-box protein FOF2 regulates floral initiation by promoting FLC expression in Arabidopsis. [PDF]
Floral initiation is regulated by various genetic pathways in response to light, temperature, hormones and developmental status; however, the molecular mechanisms underlying the interactions between different genetic pathways are not fully understood ...
He, Reqing +16 more
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Differential expression of PSAT1 in pancreatic cancer.
Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC).
openaire +1 more source
Death effector domain-containing protein induces vulnerability to cell cycle inhibition in triple-negative breast cancer [PDF]
Lacking targetable molecular drivers, triple-negative breast cancer (TNBC) is the most clinically challenging subtype of breast cancer. In this study, we reveal that Death Effector Domain-containing DNA-binding protein (DEDD), which is overexpressed in >
Guldner, Ian H. +14 more
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Cell autonomous regulation of herpes and influenza virus infection by the circadian clock. [PDF]
Viruses are intracellular pathogens that hijack host cell machinery and resources to replicate. Rather than being constant, host physiology is rhythmic, undergoing circadian (∼24 h) oscillations in many virus-relevant pathways, but whether daily rhythms ...
Edgar, Rachel S +6 more
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Metabolomic changes during cellular transformation monitored by metabolite-metabolite correlation analysis and correlated with gene expression. [PDF]
To investigate metabolic changes during cellular transformation, we used a 1H NMR based metabolite-metabolite correlation analysis (MMCA) method, which permits analysis of homeostatic mechanisms in cells at the steady state, in an inducible cell ...
Griffiths, John R +7 more
core +7 more sources
A simple and efficient transient transformation for hybrid aspen (Populus tremula × P. tremuloides). [PDF]
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Eriksson, Maria E, Takata, Naoki
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Proteomic profiling of halloysite clay nanotube exposure in intestinal cell co-culture [PDF]
Halloysite is aluminosilicate clay with a hollow tubular structure with nanoscale internal and external diameters. Assessment of halloysite biocompatibility has gained importance in view of its potential application in oral drug delivery.
Agarwal, Mangilal +5 more
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