Results 41 to 50 of about 54,159 (319)
International Journal of Tryptophan Research, 2017 Recent work indicates an intimate interaction of the tryptophan catabolite (TRYCAT) pathways with the melatonergic pathways, primarily via TRYCAT pathway induction taking tryptophan away from the production of serotonin, which is a necessary precursor ...
George Anderson, M. Maes
semanticscholar +1 more source
环境与职业医学, 2023 BackgroundDue to the limited availability of established research models, very few studies addressed the health effects and underlying mechanisms following exposure to diesel exhaust during the initiation of pulmonary respiration.
Hao NI +4 more
doaj +1 more source
Amino Acid Trp: The Far Out Impacts of Host and Commensal Tryptophan Metabolism
Frontiers in Immunology, 2021 Tryptophan (Trp) is an essential amino acid primarily derived from the diet for use by the host for protein synthesis. The intestinal tract is lined with cells, both host and microbial, that uptake and metabolize Trp to also generate important signaling ...
Heather M. Grifka-Walk +2 more
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New Trends in Aryl Hydrocarbon Receptor Biology [PDF]
Frontiers in Cell and Developmental Biology, 2016 Traditionally considered as a critical intermediate in the toxic and carcinogenic response to dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD), the Aryl hydrocarbon/Dioxin receptor (AhR) has proven to be also an important regulator of cell physiology and organ homeostasis.
Mulero-Navarro, Sonia +1 more
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The aryl hydrocarbon receptor in liver inflammation [PDF]
Seminars in Immunopathology, 2021 AbstractThe aryl hydrocarbon receptor (AHR) is a ubiquitously expressed ligand-activated transcription factor with multifaceted physiological functions. In the immune system, AHR has been unequivocally identified as a key regulatory factor that can integrate environmental, dietary, or microbial signals into innate and adaptive immune responses ...
Antonella Carambia, Fenja Amrei Schuran
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Cells, 2020 Azole fungicides, especially triazole compounds, are widely used in agriculture and as pharmaceuticals. For a considerable number of agricultural azole fungicides, the liver has been identified as the main target organ of toxicity.
Philip Marx-Stoelting +2 more
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Signaling in a polluted world: oxidative stress as an overlooked mechanism linking contaminants to animal communication [PDF]
, 2016 The capacity to communicate effectively with other individuals plays a critical role in the daily life of an individual and can have important fitness consequences.
Costantini, David, Marasco, Valeria
core +1 more source
Cell Reports, 2018 Summary: The gut microbiota plays a significant role in the progression of fatty liver disease; however, the mediators and their mechanisms remain to be elucidated. Comparing metabolite profile differences between germ-free and conventionally raised mice
Smitha Krishnan +9 more
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Endocrine-disrupting Potential of Pesticides via Nuclear Receptors and Aryl Hydrocarbon Receptor
, 2010 Nuclear receptors (NRs) and the aryl hydrocarbon receptor (AhR) form a ligand-dependent transcription factor that regulates the genes involved in key physiological functions such as cell growth and differentiation, development, homeostasis, and ...
Hiroyuki Kojima +2 more
semanticscholar +1 more source
Role of aryl hydrocarbon receptors in infection and inflammation
Frontiers in ImmunologyThe aryl hydrocarbon receptor (AhR) is a transcription factor that is activated by various ligands, including pollutants, microorganisms, and metabolic substances.
Linglan Xu +7 more
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