Results 231 to 240 of about 8,300,360 (253)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Application of Constant vs. Variable Relative Biological Effectiveness in Treatment Planning of Intensity-Modulated Proton Therapy

International Journal of Radiation Oncology Biology Physics, 2011
To investigate in a simulation study whether using a variable relative biological effectiveness (RBE) in calculation and optimization of intensity-modulated proton therapy (IMPT) instead of using an RBE of 1.1 would result in significant changes in the ...
Jan Jakob Wilkens, Peter E Huber
exaly   +2 more sources

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A Biological Perspective of Breast Cancer: Contributions of the National Surgical Adjuvant Breast and Bowel Project Clinical Trials

Ca-A Cancer Journal for Clinicians, 1991
Bernard Fisher, B Fisher
exaly  

Clinical Evidence of Variable Proton Biological Effectiveness in Pediatric Patients Treated for Ependymoma

Radiotherapy and Oncology, 2016
Jillian R Gunther, Uwe Titt, Anita Mahajan   +2 more
exaly  

Lung Cancer: New Biological Insights and Recent Therapeutic Advances

Ca-A Cancer Journal for Clinicians, 2011
Suresh S Ramalingam, Taofeek K. Owonikoko, Fadlo R Khuri   +2 more
exaly  

Relative Biological Effectiveness (RBE) Values for Proton Beam Therapy

International Journal of Radiation Oncology Biology Physics, 2002
Harald Paganetti, Andrzej Niemierko, Michael Goitein   +2 more
exaly  

Report of the AAPM TG-256 on the Relative Biological Effectiveness of Proton Beams in Radiation Therapy

Medical Physics, 2019
Robert D. Stewart, Lei Dong, Alejandro Carabe-Fernandez   +2 more
exaly