Results 11 to 20 of about 53,784 (251)

The Acute Effect of Erythropoietin on Mean Platelet Volume Levels during Hypoxia Reoxygenation Injury in Rats

open access: yesHaseki Tıp Bülteni, 2016
Aim: This biomedical study tested the effect of erythropoietin (Epo) in rat model, especially in a hypoxia-reoxygenation one. The trend of this factor was evaluated hematologically using serum mean platelets volume (MPV) values. Methods: Forty rats with
Constantinos Tsompos   +5 more
doaj   +2 more sources

Myocardial Damage Induced by Uncontrolled Reoxygenation [PDF]

open access: yesAsian Cardiovascular and Thoracic Annals, 2000
To evaluate myocardial impairment induced by uncontrolled reoxygenation, the effects of hypoxia-reoxygenation were compared with ischemia-reperfusion in isolated rat hearts. After stabilization, 2 groups (n = 8) of Langendorff-perfused rat hearts were exposed to 40 minutes of ischemia (10% of baseline flow) or hypoxia (10% of ...
A. F. Corno   +3 more
openaire   +3 more sources

The Contribution of Reoxygenation to Ischemic Brain Damage [PDF]

open access: yesJournal of Cerebral Blood Flow & Metabolism, 1991
This study examined the hypothesis that the level of postischemic reperfusion affects the severity of the resulting neuronal necrosis. In rats, tissue Po 2 % was monitored as an index of flow (reoxygenation) at four cortical sites by chronically implanted platinum electrodes.
J H, Halsey   +3 more
openaire   +3 more sources

Studies of hypoxemic/reoxygenation injury: without aortic clamping. II. Evidence for reoxygenation damage. [PDF]

open access: yesThe Journal of thoracic and cardiovascular surgery, 1995
This study tested the hypothesis that the developing heart is susceptible to oxygen-mediated damage after reintroduction of molecular oxygen and that this "unintended" reoxygenation injury causes lipid peroxidation and functional depression that may contribute to perioperative cardiac dysfunction.
Ihnken, Kai   +6 more
openaire   +3 more sources

Studies of hypoxemic/reoxygenation injury: with aortic clamping. XII. Delay of cardiac reoxygenation damage in the presence of cyanosis: a new concept of controlled cardiac reoxygenation. [PDF]

open access: yesThe Journal of thoracic and cardiovascular surgery, 1995
Twenty-one immature piglets (< 3 weeks old) underwent 30 minutes of aortic clamping with hypocalcemic glutamate/aspartate blood cardioplegia. Six piglets underwent hyperoxemic cardiopulmonary bypass and blood cardioplegia without preceding hypoxemia (control).
Morita, Kiyozo   +2 more
openaire   +3 more sources

Dynamic Metabolic Changes in Arabidopsis Seedlings under Hypoxia Stress and Subsequent Reoxygenation Recovery

open access: yesStresses, 2023
Hypoxic stress, caused by the low cellular oxygen in the events of flooding or waterlogging, limits crop productivity in many regions of the world. Hypoxic stress in plants is often dynamic and followed by a reoxygenation process that returns the oxygen ...
Xinyu Fu, Yuan Xu
doaj   +2 more sources

Down-regulation of NDRG1 promotes migration of cancer cells during reoxygenation.

open access: yesPLoS ONE, 2011
One characteristic of tumor microenvironment is oxygen fluctuation, which results from hyper-proliferation and abnormal metabolism of tumor cells as well as disorganized neo-vasculature. Reoxygenation of tumors can induce oxidative stress, which leads to
Liang-Chuan Lai   +7 more
doaj   +2 more sources

Novel Targets in a High-Altitude Pulmonary Hypertension Rat Model Based on RNA-seq and Proteomics

open access: yesFrontiers in Medicine, 2021
High-altitude pulmonary hypertension (HAPH) is a complication arising from an inability to acclimatize to high altitude and is associated with high morbidity and mortality.
Xiang Xu   +11 more
doaj   +1 more source

Myostatin Deficiency Protects C2C12 Cells from Oxidative Stress by Inhibiting Intrinsic Activation of Apoptosis

open access: yesCells, 2021
Ischemia reperfusion (IR) injury remains an important topic in clinical medicine. While a multitude of prophylactic and therapeutic strategies have been proposed, recent studies have illuminated protective effects of myostatin inhibition. This study aims
Marius Drysch   +11 more
doaj   +1 more source

Effects of acute hypoxia and reoxygenation on oxygen sensors, respiratory metabolism, oxidative stress, and apoptosis in hybrid yellow catfish “Huangyou-1”

open access: yesFish Physiology & Biochemistry, 2021
The regulation mechanism of the hybrid yellow catfish “Huangyou-1” was assessed under conditions of hypoxia and reoxygenation by examination of oxygen sensors and by monitoring respiratory metabolism, oxidative stress, and apoptosis.
Xue-Yin Pei   +9 more
semanticscholar   +1 more source

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