Results 61 to 70 of about 6,542,890 (150)
The FEBS Journal, Volume 293, Issue 5, Page 1323-1340, March 2026.Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim +8 more
wiley +1 more source
, 1993 Small nuclear (sn) ribonucleoprotein (RNP) U2 functions in the splicing of mRNA by recognizing the branch site of the unspliced pre-mRNA. When HeLa nuclear splicing extracts are centrifuged on glycerol gradients, U2 snRNPs sediment at either 12S (under ...
Sven-erik Behrens +3 more
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Nop53p is required for late 60S ribosome subunit maturation and nuclear export in yeast [PDF]
, 2005 We report that Ypl146cp/Nop53p is associated with pre-60S ribosomal complexes and localized to the nucleolus and nucleoplasm. in cells depleted of Nop53p synthesis of the rRNA components of the 60S ribosomal subunit is severely inhibited, with strikingly
Tollervey, D, Thomson, E
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SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly [PDF]
, 2005 We have isolated the human protein SNEV as downregulated in replicatively senescent cells. Sequence homology to the yeast splicing factor Prp19 suggested that SNEV might be the orthologue of Prp19 and therefore might also be involved in pre-mRNA splicing.
Grillari, Johannes +13 more
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Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Modified U1snRNAs as innovative therapeutic strategy for inherited coagulation factor deficiencies [PDF]
, 2012 The theoretical framework in which this study is framed concerns the internationalization of production dynamics of firms abroad. The international literature in this field argues that there is not a conventional definition nor a universally tested ...
Balestra, Dario
core
HNRNPK (heterogeneous nuclear ribonucleoprotein K) [PDF]
, 2010 Review on HNRNPK (heterogeneous nuclear ribonucleoprotein K), with data on DNA, on the protein encoded, and where the gene is ...
Ostrowski, J +3 more
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Molecular architecture of the human 17S U2 snRNP
, 2020 The U2 small nuclear ribonucleoprotein (snRNP) has an essential role in the selection of the precursor mRNA branch-site adenosine, the nucleophile for the first step of splicing1. Stable addition of U2 during early spliceosome formation requires the DEAD-
Hartmuth, K. +21 more
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Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8 [PDF]
, 2009 The U5 snRNA loop 1 aligns the 5' and 3' exons for ligation during the second step of pre-mRNA splicing. U5 is intimately associated with Prp8, which mediates pre-mRNA repositioning within the catalytic core of the spliceosome and interacts directly with
David Barrass, J. +5 more
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Colocalization of U1 and U2 small nuclear RNPs by immunocytochemistry
, 1984 The in situ localization of U1 and U2 snRNPs was examined, using autoantibodies directed against each of these snRNPs, by immunofluorescence and immunoelectron microscopy.
Spector, D. L.
core +1 more source