Results 131 to 140 of about 17,697 (207)

Development of a New Positron Emission Tomography Imaging Radioligand Targeting RIPK1 in the Brain and Characterization in Alzheimer's Disease

Advanced Science
Targeting receptor‐interacting protein kinase 1 (RIPK1) has emerged as a promising therapeutic stratagem for neurodegenerative disorders, particularly Alzheimer's disease (AD).
Ping Bai, Yu Lan, Yan Liu, Prasenjit Mondal, Ashley Gomm, Yulong Xu, Yanli Wang, Yongle Wang, Leyi Kang, Lili Pan, Frederick A. Bagdasarian, Madelyn Hallisey, Fleur Lobo, Breanna Varela, Se Hoon Choi, Stephen N. Gomperts, Hsiao‐Ying Wey, Shiqian Shen, Rudolph E. Tanzi, Changning Wang, Can Zhang   +20 more
doaj   +1 more source

Cell death: RIPK1 protects epithelial cells [PDF]

Nature Reviews Molecular Cell Biology, 2014
openaire   +2 more sources

RIPK1 inhibition mitigates neuroinflammation and rescues depressive-like behaviors in a mouse model of LPS-induced depression

Cell Communication and Signaling
Background Depression is often linked to inflammation in the brain. Researchers have been exploring ways to reduce this inflammation to improve depression symptoms.
Qichao Gong, Tahir Ali, Yue Hu, Ruyan Gao, Shengnan Mou, Yanhua Luo, Canyu Yang, Axiang Li, Tao Li, Liang Liang Hao, Liufang He, Xiaoming Yu, Shupeng Li   +12 more
doaj   +1 more source

Serum Level of RIPK1/3 Correlated With the Prognosis in ICU Patients With Acute Ischemic Stroke

Immunity, Inflammation and Disease
Background Acute ischemic stroke (AIS) is a common cerebrovascular disease with high mortality. AIS patients in the intensive care unit (ICU) often have severe conditions that require close monitoring and timely treatment.
Jianhong Dong, Xinli Xiong
doaj   +1 more source

RIPK1 prevents aberrant ZBP1-initiated necroptosis

Oncotarget, 2016
Berghe, Tom Vanden, Kaiser, William J.
openaire   +2 more sources

Necroptotic signaling orchestrates glioblastoma malignancy and potentiates temozolomide response. [PDF]

Cell Death Dis
Li Y, Qiu Y, Gao W, Geng L, Wu Z, Zhang T, Pan J, Lu J, Zhang D, Idris A, Hou L, Su Z, Li J.   +12 more
europepmc   +1 more source

The role of necroptosis in adiposity-based chronic disease (ABCD): A review. [PDF]

Medicine (Baltimore)
Wu Y, Bai J, Ma G.
europepmc   +1 more source

The neurotoxicant PCB-95 by increasing the neuronal transcriptional repressor REST down-regulates caspase-8 and increases Ripk1, Ripk3 and MLKL expression determining necroptotic neuronal death [PDF]

, 2017
Canzoniero, Lmt, Di Renzo, G, Formisano, L., Guida, N, Laudati, G, Mascolo, L, Molinaro, P, Montuori, P, Serani, A   +8 more
core   +1 more source

Roll with the punches: Fibroblast growth factor 10 alleviates pyroptosis of alveolar epithelial cells in different immune niches. [PDF]

Clin Transl Med
Wei T, Chen X, Xu J, Mao W, Yang Z, Wang Y, Li Y, Jin W, Chen C, Zhang C, Song Y.   +10 more
europepmc   +1 more source

Spermidine Alleviates Sepsis-Induced Acute Lung Injury through AMPK-Mediated Improvement of Necroptosis. [PDF]

Inflammation
Ye B, Jin Y, Hu S, Shao Y, Yang Q, Wu H, Liu Z.   +6 more
europepmc   +1 more source