Results 51 to 60 of about 853,838 (334)

Expression of the C-terminal family 22 carbohydratebinding module of xylanase 10B of Clostridium themocellum in tobacco plant [PDF]

open access: yes, 2009
Carbohydrate-binding modules have been shown to alter plant cell wall structural architecture. Hence, they have the potential application of being used to engineer the plant to produce tailor-made natural fibers in the cell wall.
Obembe, Olawole O.
core   +2 more sources

Regulatory role and mechanism of m6A RNA modification in human metabolic diseases

open access: yesMolecular Therapy: Oncolytics, 2021
Metabolic diseases caused by disorders in amino acids, glucose, lipid metabolism, and other metabolic risk factors show high incidences in young people, and current treatments are ineffective.
Yuliang Zhang   +8 more
doaj   +1 more source

Nanodelivery of a functional membrane receptor to manipulate cellular phenotype. [PDF]

open access: yes, 2018
Modification of membrane receptor makeup is one of the most efficient ways to control input-output signals but is usually achieved by expressing DNA or RNA-encoded proteins or by using other genome-editing methods, which can be technically challenging ...
Baikoghli, Mo   +7 more
core   +2 more sources

Cellular Dynamics of RNA Modification [PDF]

open access: yesAccounts of Chemical Research, 2011
Five decades of research have identified more than 100 ribonucleosides that are post-transcriptionally modified. Many modified nucleosides are conserved throughout bacteria, archaea, and eukaryotes, while some are unique to each branch of life. However, the cellular and functional dynamics of RNA modification remain largely unexplored, mostly because ...
Chengqi, Yi, Tao, Pan
openaire   +2 more sources

Deep-m6Am: a deep learning model for identifying N6, 2′-O-Dimethyladenosine (m6Am) sites using hybrid features

open access: yesAIMS Bioengineering
N6,2′-O-dimethyladenosine (m6Am) is a crucial RNA modification that plays a pivotal role in regulating gene expression and maintaining RNA stability. Given its dynamic involvement in various biological processes and diseases, accurately identifying m6Am ...
Islam Uddin   +3 more
doaj   +1 more source

The Role of m6A Ribonucleic Acid Modification in the Occurrence of Atherosclerosis

open access: yesFrontiers in Genetics, 2021
The N6-methyladenosine (m6A) modification is the most abundant epitranscriptomic modification in eukaryotic messenger RNA (mRNA). The m6A modification process is jointly regulated by various enzymes and proteins, such as methyltransferases, demethylases ...
Jie Fu   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Research Progress on Epigenetic Regulation of Fungal Secondary Metabolism

open access: yesGuangdong nongye kexue
Fungi are capable of synthesizing a wide array of secondary metabolites with diverse structures and biological activities, which have significant applications in agriculture, medicine, food, and industry.
Siyi TAN   +3 more
doaj   +1 more source

Bionanomaterials from plant viruses [PDF]

open access: yes, 2015
Plant virus capsids have emerged as useful biotemplates for material synthesis. All plant virus capsids are assembled with high-precision, three-dimensional structures providing nanoscale architectures that are highly monodisperse, can be produced in ...
Aljabali, Alaa A. A., Evans, David
core   +1 more source

Non-mammalian model organisms in epigenetic research : an overview [PDF]

open access: yes, 2020
Recent advances in sequencing technology and genome editing tools had an indisputably enormous impact on our understanding of complex biological pathways and their genetic and epigenetic regulation.
Baruah, Sri Kartik   +3 more
core   +2 more sources

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