Results 11 to 20 of about 35,307 (294)
Muscle growth by sarcomere divisions
Science AdvancesThe sarcomere is the elementary contractile unit of muscles. Adult muscle cells are large and chain thousands of sarcomeres into long periodic myofibrils that attach to the skeleton. During development, muscle cells must increase in length to maintain the mechanical connection to the growing skeleton. How muscles add new sarcomeres
Rodier, Clement +8 more
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Tension-driven multi-scale self-organisation in human iPSC-derived muscle fibers
eLife, 2022 Human muscle is a hierarchically organised tissue with its contractile cells called myofibers packed into large myofiber bundles. Each myofiber contains periodic myofibrils built by hundreds of contractile sarcomeres that generate large mechanical forces.
Qiyan Mao +16 more
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, 2022 Dataset of sarcomere organization, including filament directionality, network density, sarcomere length and z-Disc ...
Heiko Lemcke
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Active Viscoelasticity of Sarcomeres [PDF]
Frontiers in Robotics and AI, 2018 The perturbation response of muscle is important for the versatile, stable and agile control capabilities of animals. Muscle resists being stretched by developing forces in the passive tissues and in the active crossbridges. This review focuses on the active perturbation response of the sarcomere. The active response exhibits typical stress relaxation,
Khoi D. Nguyen 0002 +2 more
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Distorting the sarcomere [PDF]
Journal of General Physiology, 2010 One of the goals of cardiovascular science is to create a mathematical model of the heart that can predict ventricular function in healthy and diseased states, and that can be used to help improve treatment options for patients with heart disease. To be clinically useful, the model will have to include structural information about the shapes of the ...
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Biomechanical Properties of the Sarcolemma and Costameres of Skeletal Muscle Lacking Desmin
Frontiers in Physiology, 2021 Intermediate filaments (IFs), composed primarily by desmin and keratins, link the myofibrils to each other, to intracellular organelles, and to the sarcolemma.
Karla P. Garcia-Pelagio, Robert J. Bloch
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Spontaneous sarcomere dynamics [PDF]
Chaos: An Interdisciplinary Journal of Nonlinear Science, 2010 Sarcomeres are the basic force generating units of striated muscles and consist of an interdigitating arrangement of actin and myosin filaments. While muscle contraction is usually triggered by neural signals, which eventually set myosin motors into motion, isolated sarcomeres can oscillate spontaneously between a contracted and a relaxed state.
Gunther, Stefan, Kruse, Karsten
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Structural investigation of the molecular mechanisms underlying titin elasticity and signaling [PDF]
, 2010 Titin is a giant protein that spans >1µm from the Z-disc to the M-line, forming an intrasarcomeric filament system in vertebrate striated muscle, which is not only essential for the assembly of the sarcomere, but also critical for myofibril signaling and
Castelmur, Eleonore von
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Sarcomere and mitochondrial measurements.
, 2023 Spreadsheet “Sarcomere Length”: Quantification of the Sarcomere Length of cardiomyocytes (related to Fig 2B); Spreadsheet “Mitochondrial size”: Quantification of the Mitochondrial size of cardiomyocytes (related to Fig 2D). (XLSX)
Shengshou Hu (194962) +9 more
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Frontiers in Physiology, 2023 Introduction: Adult patients with atrial septal defects (ASD), the most common form of adult congenital heart disease, often die of arrhythmias, and the immaturity of cardiomyocytes contributes significantly to arrhythmias.
Zhuoya Dong +13 more
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