Results 131 to 140 of about 30,415 (217)
Regulated Cell Death in Idiopathic Pulmonary Fibrosis
The FASEB Journal, Volume 40, Issue 9, 15 May 2026.This graphical abstract illustrates regulated cell death (RCD) across key pulmonary cell types—including alveolar epithelial cells, fibroblasts, macrophages, and endothelial cells—modulated through a dynamic death modulation network within the IPF microenvironment.
Xiaoyue Pan +10 more
wiley +1 more source
p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells [PDF]
, 2017 Cheruiyot, Abigael +5 more
core +2 more sources
Cancer Medicine, Volume 15, Issue 5, May 2026.The study corroborates the prognostic value of previously identified risk factors impacting progression‐free survival (PFS) and overall survival (OS) in older patients with extensive‐stage small cell lung cancer (ES‐SCLC). The figure was created with Microsoft PowerPoint.
Jiayin Liu +14 more
wiley +1 more source
When Timing Matters Most: Early Relapse Outweighs Baseline Risk in Myeloma
Cancer Medicine, Volume 15, Issue 5, May 2026.ABSTRACT Multiple myeloma outcomes vary widely, with risk stratification typically based on baseline characteristics. Functionally high‐risk multiple myeloma (FHRMM), defined by early relapse within 12 months of initial therapy or autologous stem cell transplant, is associated with poor prognosis.
Xinhe Shan +1 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 3, May 2026.ABSTRACT Ergothioneine (EGT), a natural thiol derivative, has gained attention as a geroprotective nutraceutical. Preclinical research shows EGT scavenges free radicals, maintains mitochondrial integrity, slows telomere erosion, and regulates proteostasis via autophagy and senescent cell clearance.
Tian‐Tian Tian +3 more
wiley +1 more source
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy
Journal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy. Created in BioRender. Jain, E. (2026) https://BioRender.com/x4f9o8g. ABSTRACT Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain.
Era Jain, Paul Nana Kwame Sagoe
wiley +1 more source
Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.ABSTRACT Osteoarthritis (OA) remains without disease‐modifying sssstherapies, in part due to biological heterogeneity and a hostile joint microenvironment that undermines one‐size‐fits‐all interventions. Extracellular vesicles (EVs) play a dual role in OA pathophysiology: endogenous EVs disseminate pro‐inflammatory and catabolic signals that propagate ...
Duc‐Hiep Bach +2 more
wiley +1 more source
Spatiotemporal Transcriptomics Characterizes Immune Microenvironment During Mouse Liver Aging
Aging Cell, Volume 25, Issue 5, May 2026.T cells are the most dynamically altered immune population in the aged liver. Accumulation of CD8+ Tex in aged livers. Spatial enrichment of CD8+ Tex in the portal vein zone. PP hepatocytes promote T cell exhaustion via Lpin1. T cell exhaustion correlates with liver disease progression.
Jiahua Lu +7 more
wiley +1 more source
Journal of Fasa University of Medical Sciences, 2012 Background & Objective: Sulfasalazine (SASP) is a drug used for the treatment of inflammatory bowel diseases. SASP causes testicular damage. The aim of this study was to verify whether or not an additional supply of vitamin E or C or together prevent the
Mojbaba Keshavars +5 more
doaj
Diminished and Altered Cellular Senescence Response in Delayed Wound Healing of Aging
Aging Cell, Volume 25, Issue 5, May 2026.Acute wound healing in young skin is supported by a transient population of senescent fibroblasts with proreparative, ECM‐remodeling functions. Aging disrupts both the induction and functional identity of these cells, contributing to delayed wound closure and impaired tissue repair.
Maria Shvedova +5 more
wiley +1 more source