Results 201 to 210 of about 22,235 (292)

Cardiotrophin 1: A Novel SASP Marker in Senescent MCF­7 Cells

Cellular senescence is a permanent arrest of the cell cycle in response to many stress factors and is characterized by excessive secretory  ...
Şimay Demir, Yaprak Dilber, Özdemir, Aysun, Ark, Mustafa, Tayyar, Tuğçe   +3 more
core  

Vicatia thibetica de Boiss Crude Polysaccharide Delay the Aging of the Heart and Kidneys

Food Bioengineering, Volume 5, Issue 2, Page 278-289, June 2026.
Vicatia thibetica de Boiss crude polysaccharide (VTCP) attenuates cardiorenal aging by reducing oxidative stress, suppressing inflammation, and alleviating fibrosis. In naturally aged mice, VTCP remodels the gut microbiota, enriching beneficial short‐chain fatty acid‐producing bacteria. We propose that VTCP protects the heart and kidneys via modulation
Daoxu Zhang, Chengyi Wu, Zhiyang Ding, Yunyu Hong, Yehan Lu, Kunpeng Zhou, Ruixuan Deng, Laijia Li, Chao Li, Yongcheng Yang, Conglong Xia, Jian Li, Wenwen Liu, Faliang An, Zelan Hu   +14 more
wiley   +1 more source

Editorial: Unraveling inflammaging: a pathway to prevent age-related disease in animals, volume II. [PDF]

Front Vet Sci
Arai T.
europepmc   +1 more source

SASP in peripartum cardiomyopathy and preeclampsia

Nature Aging
openaire   +2 more sources

Polygonati Rhizoma Attenuates Oxidative Stress‐Induced Senescence in Periodontal Ligament Stem Cells

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Network pharmacology identified the potential targets and pathways of Polygonati Rhizoma (PR) against aging‐related periodontitis through PPI, GO/KEGG enrichment, and molecular docking. Experimental validation in a D‐galactose‐induced senescence model of periodontal ligament stem cells showed that PR‐medicated serum attenuated cellular senescence and ...
Xinran Feng, Ying An, Fanfan Hou, Qian Guo, Shanshan Cai, Hongbin Xu, Youfu He   +6 more
wiley   +1 more source

Nuclear export of R-loop by the DDX1 and XPO1 complex promotes senescence-associated secretory phenotype and inflammaging. [PDF]

Nat Aging
Hao X, Zhao B, Yan Q, Yano M, Matsuoka A, Qi Y, Liao L, Zielinski RJ, Tang HY, Kossenkov AV, Zal MA, Sarma K, Zhang R.   +12 more
europepmc   +1 more source

Solanesol Alleviates Perfluoroheptanoic Acid‐Induced Premature Senescence in Human Skin Fibroblasts via RNA Methylation

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Perfluoroheptanoic acid (PFHpA) induces premature senescence in normal human skin fibroblasts (HSFs), as characterized by decreased cell viability, increased SA‐β‐gal staining, impaired wound healing, cell cycle dysregulation, elevated ROS levels, and upregulated SASP mRNA expression.
Jiaqi Fu, Tingting Huang, Guisong Li, Xinyu Zhang, Luyi Tan, Chenyu Zhu, Wenji Zhang, Wenjuan Zhang   +7 more
wiley   +1 more source

Immunosenescence in Idiopathic Pulmonary Fibrosis. [PDF]

J Inflamm Res
Xiao S, Li Z, Zhang H, Cai W, Yu S, Song X.   +5 more
europepmc   +1 more source

The Rising Burden of Osteosarcopenia in Older Adults: A Narrative Review of Pathophysiology, Diagnostic Challenges, and Therapeutic Perspectives

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Osteosarcopenia, defined as the coexistence of osteoporosis and sarcopenia, is an emerging geriatric syndrome linked to the musculoskeletal decline associated with aging. It is correlated with an increased risk of falls, fractures, disability, and mortality.
Javeria Taj, Rabia Zafar, Joshua Ekouo, Ayesha Junaid, Dujardin Makeda, Kinza Latif, Hermann Yokolo   +6 more
wiley   +1 more source

PI3K/mTOR inhibition attenuates cigarette smoke-induced senescence and SASP in oral fibroblasts: implications for tumor microenvironment remodeling. [PDF]

Front Cell Dev Biol
Flacco N, Estornut C, Roger I, Ribera P, Sánchez-Herrera G, Trujillo-Barbera S, Pérez-Leal M.   +6 more
europepmc   +1 more source