Aging Cell, Volume 25, Issue 6, June 2026.Oral administration of Lactobacillus paracasei L9 (L9) reshapes the gut microbiota, specifically increasing the abundance of short‐chain fatty acid (SCFA)‐producing bacteria (e.g., Blautia), thereby leading to a significant elevation of serum propionic acid (97% increase) and butyric acid (193% increase).
Ran Bi +10 more
wiley +1 more source
Senescent Factors Suppress Innate Antiviral Immunity in Aged Mice via Two Distinct Mechanisms. [PDF]
Aging CellZhang X, Zhang Q, Wang L, Li S, Shu HB.
europepmc +1 more source
Magnesium as a Bioenergetic Checkpoint Linking Mitochondrial Function, Metabolic Disease, and Aging
Aging Cell, Volume 25, Issue 6, June 2026.This review positions magnesium as a central bioenergetic checkpoint that orchestrates mitochondrial function and metabolic resilience. By defining the functional ATP pool and stabilizing mitochondrial performance, magnesium homeostasis serves as a mechanistic link between renal handling, metabolic disease, and the aging process.
Chien‐Wei Huang +6 more
wiley +1 more source
The Emerging Role of Senolytics as a Next-Generation Strategy Against Glioma Recurrence: A Narrative Review. [PDF]
Cancers (Basel)Filardo A +10 more
europepmc +1 more source
Drug‐induced hypersensitivity syndrome followed by exacerbation of Crohn's disease
Pediatric Investigation, Volume 10, Issue 3, Page 288-290, June 2026.
Mei Kamidani +10 more
wiley +1 more source
The Evolving Landscape of Clinical Aging Clocks: From Epigenetic to Multi‐Omics Integration
Aging Cell, Volume 25, Issue 6, June 2026.Multi‐omics aging clocks capture biological heterogeneity beyond single‐omics models, improving risk stratification. Key challenges include unknown biological meaning, timescale mismatches, and validation gaps. Future clocks must distinguish pathological damage from adaptive remodeling—damage accumulation is the most actionable target for anti‐aging ...
Liying Liu +13 more
wiley +1 more source
Therapy-Induced Senescence Shapes Extracellular Matrix Niches and Fibroblast Function in Head and Neck Squamous Cell Carcinoma. [PDF]
Cancers (Basel)Montero-Vergara J +3 more
europepmc +1 more source
Aging Cell, Volume 25, Issue 6, June 2026.Senescent myoblasts exhibit dysregulated Akt/mTORC1 signalling. Antioxidants can alleviate this dysregulation, as well as other downstream senescent phenotypes. Moreover, prolonged antioxidant treatment can selectively induce cell death in senescent myoblasts, suggesting that these cells are more susceptible to reductive stress.
Vladimir Belhac +13 more
wiley +1 more source
Therapy-induced senescent cancer cells as bidirectional regulators of antitumor immunity and resistance in the tumor microenvironment. [PDF]
Cell Death DisChoi M, Lee D, Yang WH, Cha JH.
europepmc +1 more source
Tubulointerstitial nephritis and uveitis syndrome in children: What to keep an eye on
Acta Ophthalmologica, Volume 104, Issue 4, Page e443-e452, June 2026.Abstract Purpose The purpose of this study was to determine the disease course in patients with tubulointerstitial nephritis and uveitis (TINU) syndrome, focusing on long‐term outcome and the incidence of complications such as chronic kidney disease (CKD).
Jytte Hendrikse +4 more
wiley +1 more source