Results 241 to 250 of about 26,150 (274)
Senescence and Cancer: Role of Nitric Oxide (NO) in SASP [PDF]
Cancers, 2020 Cellular senescence is a cell state involved in both physiological and pathological processes such as age-related diseases and cancer. While the mechanism of senescence is now well known, its role in tumorigenesis still remains very controversial.
Catherine Paul +2 more
exaly +4 more sources
Calcified Tissue International, 2023 Abstract Senescence is a complex cell state characterized by stable cell cycle arrest and a unique secretory pattern known as the senescence-associated secretory phenotype (SASP). The SASP factors, which are heterogeneous and tissue specific, normally include chemokines, cytokines, growth factors, adhesion molecules, and lipid ...
Mei Wan
exaly +3 more sources
Defective Mitochondria Ignite the SASP [PDF]
Nature Reviews Molecular Cell Biology, 2020 Defective mitochondria in senescent cells activate a signalling pathway that promotes the senescence-associated secretory phenotype and inflammation.
Eytan Zlotorynski
exaly +3 more sources