Evaluation of Exploratory Fluid Biomarker Results from a Phase 1 Senolytic Trial in Mild Alzheimer\u27s Disease [PDF]
Senescent cell accumulation contributes to the progression of age-related disorders including Alzheimer\u27s disease (AD). Clinical trials evaluating senolytics, drugs that clear senescent cells, are underway, but lack standardized outcome measures.
Barthelemy, Nicolas +10 more
core +1 more source
Senolytics improve muscle adaptation in old mice
Aging, 2023 Dungan, Cory M., Peterson, Charlotte A.
openaire +2 more sources
Senotherapeutics for Brain Aging Management. [PDF]
Neurol IntSaliev T, Singh PB.
europepmc +1 more source
Senescence Modulation: An Applied Science Review of Strategies in Anti-Aging, Regenerative Aesthetics, and Oncology Therapy. [PDF]
Curr Issues Mol BiolKusmanto SJ.
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The geroscience hypothesis: Economic paradigms and pharmacological strategies for healthspan extension. [PDF]
J Taibah Univ Med SciAlotaibi AF +4 more
europepmc +1 more source
Senolytics as Modulators of Critical Signaling Pathways: a Promising Strategy to Combat Brain Aging and Neurodegenerative Disorders. [PDF]
Mol NeurobiolSingh I, Singh AK.
europepmc +1 more source
Senescent endothelial cells: key commanders of the cellular communication network within atherosclerotic plaques. [PDF]
Front ImmunolXie F +6 more
europepmc +1 more source
Partial Reprogramming Is Conserved from Insect to Mammal. [PDF]
CellsTolwinski NS +3 more
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Towards a personalized approach in senolytic trials. [PDF]
Nat AgingKhosla S, Monroe DG, Farr JN.
europepmc +1 more source
Targeting senescent microglia in progressive multiple sclerosis: a geroscience-informed approach. [PDF]
Front ImmunolAtkinson J +5 more
europepmc +1 more source