Gastrin attenuates sepsis-induced myocardial dysfunction by down-regulation of TLR4 expression in macrophages [PDF]
Acta Pharmaceutica Sinica B, 2023 Myocardial dysfunction is the most serious complication of sepsis. Sepsis-induced myocardial dysfunction (SMD) is often associated with gastrointestinal dysfunction, but its pathophysiological significance remains unclear.
Dandong Fang +17 more
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Omics-based integrative analysis of sepsis-induced myocardial dysfunction [PDF]
Journal of International Medical ResearchObjective Sepsis-induced myocardial dysfunction is a common complication of sepsis, characterized by high mortality and an unclear underlying mechanism.
Jie-Wen Zhao +4 more
doaj +3 more sources
Research Progress on Mechanisms and Treatment of Sepsis-Induced Myocardial Dysfunction [PDF]
International Journal of General MedicineYujie Hao, Runmin Liu, Hao Wang, Tao Rui, Junfang Guo Division of Cardiology, Department of Medicine, the Affiliated People’s Hospital of Jiangsu University, Zhenjiang, Jiangsu, People’s Republic of ChinaCorrespondence: Junfang Guo, Email zjyyxngjf@163 ...
Hao Y, Liu R, Wang H, Rui T, Guo J
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IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis [PDF]
iScience, 2023 Summary: Cardiac dysfunction is a well-recognized complication of sepsis and seriously affects the prognosis of sepsis patients. IL-30 has been reported to exert anti-inflammatory effects in various diseases.
Mengmeng Zhao +12 more
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Therapeutic S100A8/A9 blockade inhibits myocardial and systemic inflammation and mitigates sepsis-induced myocardial dysfunction [PDF]
Critical Care, 2023 Background and Aims The triggering factors of sepsis-induced myocardial dysfunction (SIMD) are poorly understood and are not addressed by current treatments.
Gabriel Jakobsson +14 more
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Lipocalin 10 as a New Prognostic Biomarker in Sepsis-Induced Myocardial Dysfunction and Mortality: A Pilot Study [PDF]
Mediators of Inflammation, 2021 Introduction. Sepsis-induced myocardial dysfunction (SIMD) is the most common complications of sepsis and septic shock with extremely high incidence and mortality.
Lu Wang +6 more
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Combatting sepsis-induced myocardial dysfunction: emerging mechanisms and immunomodulatory breakthroughs [PDF]
Frontiers in ImmunologySepsis-induced myocardial dysfunction (SIMD) critically contributes to mortality in systemic inflammatory responses, driven by multifaceted mechanisms including dysregulated inflammation, immunosuppression, oxidative stress, and autonomic dysfunction ...
Can Liu +15 more
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Inflammatory mechanisms and intervention strategies for sepsis-induced myocardial dysfunction. [PDF]
Immun Inflamm Dis, 2023 Nong Y, Wei X, Yu D.
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Epigallocatechin-3-gallate protects sepsis‐induced myocardial dysfunction by inhibiting the nuclear factor-κB signaling pathway [PDF]
HeliyonSepsis-induced myocardial dysfunction (SIMD) has become one of the most lethal complications of sepsis, while the treatment was limited by a shortage of pertinent drugs.
Bei Chen +6 more
doaj +2 more sources
New insights of necroptosis and immune infiltration in sepsis-induced myocardial dysfunction from bioinformatics analysis through RNA-seq in mice. [PDF]
Front Cell Infect Microbiol, 2022 Du Y +6 more
europepmc +2 more sources