Results 11 to 20 of about 26,464 (199)
Mitochondria-endoplasmic reticulum contacts in sepsis-induced myocardial dysfunction. [PDF]
Front Cell Dev Biol, 2022 Mitochondrial and endoplasmic reticulum (ER) are important intracellular organelles. The sites that mitochondrial and ER are closely related in structure and function are called Mitochondria-ER contacts (MERCs). MERCs are involved in a variety of biological processes, including calcium signaling, lipid synthesis and transport, autophagy, mitochondrial ...
Jiang T, Wang Q, Lv J, Lin L.
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Levosimendan for sepsis-induced myocardial dysfunction: friend or foe? [PDF]
Front Cardiovasc MedSepsis-induced myocardial dysfunction (SIMD) involves reversible myocardial dysfunction. The use of inotropes can restore adequate cardiac output and tissue perfusion, but conventional inotropes, such as dobutamine and adrenaline, have limited efficacy in such situations. Levosimendan is a novel inotrope that acts in a catecholamine-independent manner.
Du X, Xiong F, Hou Y, Yu X, Pan P.
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Sepsis-Induced myocardial dysfunction: heterogeneity of functional effects and clinical significance. [PDF]
Front Cardiovasc Med, 2023 Sepsis is a life-threatening disease state characterized by organ dysfunction and a dysregulated response to infection. The heart is one of the many organs affected by sepsis, in an entity termed sepsis-induced cardiomyopathy. This was initially used to describe a reversible depression in ejection fraction with ventricular dilation but advances in ...
Shvilkina T, Shapiro N.
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Sepsis-induced cardiac dysfunction: a review of pathophysiology [PDF]
Acute and Critical Care, 2020 It is well known that cardiac dysfunction in sepsis is associated with significantly increased mortality. The pathophysiology of sepsis-induced cardiac dysfunction can be summarized as involving impaired myocardial circulation, direct myocardial ...
Reverien Habimana +5 more
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Mitophagy Regulators as Novel Targets in Sepsis-Induced Myocardial Dysfunction. [PDF]
JACC Basic Transl SciFriedrich K, Kappert K.
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Association Between Gut Dysbiosis and Sepsis-Induced Myocardial Dysfunction in Patients With Sepsis or Septic Shock. [PDF]
Front Cell Infect Microbiol, 2022 Chen Y +8 more
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Frontiers in Cell and Developmental Biology, 2021 Myocardial dysfunction is a serious consequence of sepsis and contributes to high mortality. Currently, the molecular mechanism of myocardial dysfunction induced by sepsis remains unclear.
Shanshan Dai +7 more
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Loss of Hepatic Angiotensinogen Attenuates Sepsis-Induced Myocardial Dysfunction [PDF]
Circulation Research, 2021 Rationale: The renin-angiotensin system is a complex regulatory network that maintains normal physiological functions. The role of the renin-angiotensin system in sepsis-induced myocardial dysfunction (SIMD) is poorly defined.
Jiabing Rong +12 more
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Frontiers in Pharmacology, 2021 Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis-induced circulatory and cardiac dysfunction is associated with high mortality rates.
Wenqing Ji +11 more
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Pathophysiology of sepsis-induced myocardial dysfunction [PDF]
Military Medical Research, 2016 Sepsis-induced myocardial dysfunction is a common complication in septic patients and is associated with increased mortality. In the clinical setting, it was once believed that myocardial dysfunction was not a major pathological process in the septic patients, at least in part, due to the unavailability of suitable clinical markers to assess intrinsic ...
Lv, Xiuxiu, Wang, Huadong
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