Results 91 to 100 of about 10,790 (159)

Electroacupuncture pretreatment alleviated cerebral ischemia-reperfusion injury via suppressing autophagy in cerebral cortex tissue in rats

针刺研究, 2019
ObjectiveTo investigate the effect of electroacupuncture(EA)preconditioning on autophagy in cerebral cortex tissues of rats with cerebral ischemia-reperfusion injury(CIRI),so as to explore its mechanisms underlying improvement of CIRI.MethodsThirty-three
HUANG Ya-guang, YANG Song-bai, DU Li-peng, CAI San-jin, FENG Zhi-tao, MEI Zhi-gang   +5 more
doaj  

Immunoexpression of p62/SQSTM1/Sequestosome-1 in human primary and recurrent IDH1/2 wild-type glioblastoma: A pilot study. [PDF]

Oncol Lett, 2022
Ieni A, Pizzimenti C, Broggi G, Caltabiano R, Germanò A, Barbagallo GMV, Vigneri P, Giuffrè G, Tuccari G.   +8 more
europepmc   +1 more source

Sequestosome 1-P62 : a new promoter of melanoma progression. [PDF]

, 2013
Melanoma is an extremely aggressive type of cancer, whose incidence continues to increase worldwide. Despite of new recently approved therapies, melanoma remains highly resistant to treatment and relapses are frequently seen in clinical practice. Thus, the identification of new mechanisms of melanoma progression and translation of this knowledge ...
openaire   +1 more source

Constitutive Activation of p62/Sequestosome-1-Mediated Proteaphagy Regulates Proteolysis and Impairs Cell Death in Bortezomib-Resistant Mantle Cell Lymphoma. [PDF]

Cancers (Basel), 2022
Quinet G, Xolalpa W, Reyes-Garau D, Profitós-Pelejà N, Azkargorta M, Ceccato L, Gonzalez-Santamarta M, Marsal M, Andilla J, Aillet F, Bosch F, Elortza F, Loza-Alvarez P, Sola B, Coux O, Matthiesen R, Roué G, Rodriguez MS.   +17 more
europepmc   +1 more source

Spermidine induces cytoprotective autophagy of female germline stem cells in vitro and ameliorates aging caused by oxidative stress through upregulated sequestosome-1/p62 expression. [PDF]

Cell Biosci, 2021
Yuan X, Tian GG, Pei X, Hu X, Wu J.
europepmc   +1 more source

Targeted delivery of glucocerebrosidase to lysosomes: The LYSOTAC (LYSOsome-TArgeting Chimera) technology

Asian Journal of Pharmaceutical Sciences
Lysosomal storage diseases (LSDs) are a group of inherited metabolic disorders caused by misfolding of lysosomal proteins and their degradation via endoplasmic reticulum-associated degradation (ERAD).
Hee-Yeon Kim, Eun Nam Choi, Gee Eun Lee, Sanghwa Yoon, Su Ran Mun, Eui Jung Jung, Minji Kim, Hyomin Lim, Yang Jae Kang, Woo-Jae Park, Yong Tae Kwon, Joo-Won Park   +11 more
doaj   +1 more source

Moxibustion improves cardiac function by up-regulating autophagy-related proteins of cardiomyocytes in rats with chronic heart failure

针刺研究, 2019
Objective To observe the effect of moxibustion on cardiac function and the expression of autophagy-related proteins microtubule-associated protein 1 light chain 3(LC3)and selective autophagy receptor signaling adaptor sequestosome 1(SQSTM1/p62)in rats ...
LIU Na-na, JIA Xue-zhao, WANG Jing, ZHU Guo-qi, LI Dan, LI Qing-ling, MA Qiang   +6 more
doaj  

Palmitic acid-triggered B7H3 palmitoylation promotes immune escape

Nature Communications
Colorectal cancer responds poorly to immune checkpoint blockade in most patients with microsatellite-stable (MSS) tumors, highlighting the need for alternative targets.
Zejun Rao, Changsheng Huang, Qi Wu, Mao Li, Anyi Liu, Tong Zhu, Wangshuo Yang, Lanlan Yin, Shengyu Zhu, Xiaowei She, Chengxin Yu, Lang Liu, Pengcheng Li, Yucong Bai, Dongjing Zhang, Tianci Xie, Xiang Liu, Lu Liu, Feng Xu, Guihua Wang, Junbo Hu, Xuelai Luo   +21 more
doaj   +1 more source

Sequestosome-1 [PDF]

, 2020
openaire   +1 more source

Laetiporus sulphureus polysaccharides ameliorate chronic alcoholic liver disease by activating p62/Nrf2, AMPK pathways and reshaping gut microbiota

Food Science and Human Wellness
One novel enzymatic-extractable polysaccharide (ES1) from fruiting bodies of Laetiporus sulphureus was obtained by isolation and purification using a DEAE Seplife FF chromatographic column and a Sephacryl S-400HR column.
Huajie Zhao, Liang Liu, Ningning Liu, Baoguo Deng, Min Li, Duan Li, Le Jia, Ge Wang, Fan Yang   +8 more
doaj   +1 more source