Results 21 to 30 of about 1,840 (184)

Effects of Sinensetin, Eupatilin, and Jaceosidin on Human Melanogenesis: A Pilot Study

Future Pharmacology
Background/Objectives: Flavones, a class of plant-based flavonoids, have demonstrated conflicting anti-melanogenic activities in mouse and human melanocytes.
Shilpi Goenka
doaj   +2 more sources

Analysis of Polyphenols from Polygala major Jacq. [PDF]

Antioxidants
Plant polyphenols have significant importance due to their potential health benefits. Polygala major Jacq. is commonly found in Asia and has a long history of use in traditional medicine.
Semra Yılmazer Keskin, Ayşe Avcı, Lana Arif Ali Ali, Can Serkan Keskin   +3 more
doaj   +2 more sources

Evaluation of Sinensetin Derived From Flavonoids-Rich Orthosiphon Stamineus as a New Radiosensitizer in MDA-MB-231 and T47D as Breast Cancer Cell Lines [PDF]

Iranian Journal of Medical Physics, 2023
Introduction: Breast cancer is one of the most prevalent diseases around the world. Breast cancer patients treated with radiation may face Side effects as well as cancer recurrence. Some polyphenols exhibit antioxidant effects.
Nakisa Rezakhani, Bahram Goliaei, Fereshte Mahdizade, Alireza Nikoofar, Hoda Keshmiri Neghab, -Mohammad Hasan Soheilifar, Seyedeh Sara Azadeh, Bahareh Bigdeli   +7 more
doaj   +1 more source

Identification and Therapeutic Potential of Polymethoxylated Flavones in Citri Reticulatae Pericarpium for Alzheimer’s Disease: Targeting Neuroinflammation [PDF]

Molecules
Neuroinflammation is a significant driving force in the pathogenesis and progression of central nervous system (CNS) disorders. Polymethoxylated flavones (PMFs), the key lipid-soluble constituents in Citri Reticulatae Pericarpium (CRP), exhibit excellent
Xinyu Wang, Zirong Yi, Yiming Zhang, Jing Zhang, Xueyan Li, Dongying Qi, Qianqian Wang, Xiaoyu Chai, Huan Liu, Guopeng Wang, Yanli Pan, Yang Liu, Guohua Yu   +12 more
doaj   +2 more sources

<i>Exocarpium Citri Grandis</i> Ameliorates Metabolic Disorders by Inhibiting Inflammatory Responses and NLRP3 Inflammasome Activation. [PDF]

Food Sci Nutr
Exocarpium Citri Grandis (ECG, Huajuhong in Chinese), as the fruit of a plant that can be used both as medicine and food, has gained attention for hypolipidemic and anti‐obesity effects. To our knowledge, this is an innovative study based on in vivo and in vitro experiments aimed at exploring the pharmacological mechanisms of ECG in ameliorating MS ...
Chen T, Wu X, Wang D, Cui T, Li J, Zhang Z, Qiu M, Ma C, Liu H, Gao Y, Zeng J, Li H, Huang J.   +12 more
europepmc   +2 more sources

Exploring the Mechanism Whereby Sinensetin Delays the Progression of Pulmonary Fibrosis Based on Network Pharmacology and Pulmonary Fibrosis Models

Frontiers in Pharmacology, 2021
The incidence of pulmonary fibrosis (PF), a progressively fatal disease, has increased in recent years. However, there are no effective medicines available. Previous results have shown that sinensetin probably has some curative effects on PF.
Yong Xu, Yong Xu, Wen-Lu Hang, Wen-Lu Hang, Xian-Mei Zhou, Xian-Mei Zhou, Qi Wu   +6 more
doaj   +1 more source

Optimization Method and Stability Test to Determinate Luteolin, Quercetin, Apigenin, and Sinensetin Levels in Herbal Medicines Using TLC-Densitometry

Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2022
Background: Nephrolithiasis is a condition in which there are one or more kidney stones in the pelvis or calyces. Luteolin, quercetin, apigenin, and sinensetin are marker compounds in the extracts of Plantago major, Sonchus arvensis, Strobilanthes ...
Muhammad Hidayatullah, Mochammad Yuwono, Riesta Primaharinastiti   +2 more
doaj   +1 more source

Sinensetin suppresses breast cancer cell progression via Wnt/β-catenin pathway inhibition. [PDF]

Transl Cancer Res
Although there are many treatments for breast cancer, such as surgery, radiotherapy, chemotherapy, estrogen receptor antagonists, immune checkpoint inhibitors and so on. However, safer and more effective therapeutic drugs for breast cancer are needed.
Zhu S, Meng L, Wei P, Gu G, Duan K.
europepmc   +3 more sources

HPLC Method Optimization for Simultaneous Determination of Quercetin, Luteolin, Sinensetin, and Stigmasterol in Herbal Medicines

Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2022
Background: Quercetin, luteolin, sinensetin and stigmasterol each is the main marker compound in extracts of Sonchus arvensis, Plantago major, Orthosiphon stamineus, and Strobilanthes crispus, respectively.
Asih Imulda Hari Purwani, Riesta Primaharinastiti, Mochammad Yuwono   +2 more
doaj   +1 more source

Sinensetin Reduces Osteoarthritis Pathology in the Tert-Butyl Hydroperoxide-Treated Chondrocytes and the Destabilization of the Medial Meniscus Model Mice via the AMPK/mTOR Signaling Pathway

Frontiers in Pharmacology, 2021
As a common degenerative disease, osteoarthritis (OA) usually causes disability in the elderly and socioeconomic burden. Previous studies have shown that proper autophagy has a protective effect on OA.
Wenxian Zhou, Wenxian Zhou, Wenxian Zhou, Yifeng Shi, Yifeng Shi, Yifeng Shi, Hui Wang, Hui Wang, Hui Wang, Caiyu Yu, Huanqing Zhu, Aimin Wu, Aimin Wu, Aimin Wu   +13 more
doaj   +1 more source