Results 161 to 170 of about 17,501 (228)

The Dual Role of SLC7A11 in Colorectal Cancer Ferroptosis: From Molecular Mechanisms to Therapeutic Opportunities. [PDF]

Onco Targets Ther
Hu S, Wang Y, Tian G, Qiu Z.
europepmc   +1 more source

Role of Disulfidptosis in the Local Inflammatory Response of Atopic Dermatitis

Clinical and Translational Allergy, Volume 16, Issue 3, March 2026.
ABSTRACT Background Understanding cell death pathways is critical for elucidating the mechanisms underlying inflammation in atopic dermatitis (AD). This study investigates the role of disulfidptosis, a novel form of programmed cell death, in AD pathogenesis.
Dong‐Mei Zhou, Cheng Chen, Yuan‐Fen Liao, Xi‐Meng Ma, Xin‐Hui Gong, Cheng‐Jun Cui, Yu‐Bao Cui   +6 more
wiley   +1 more source

血清SLC7A11、CPT1A在宫颈癌中表达水平与患者临床病理特征及预后的关系

Zhongguo shiyan zhenduanxue
目的分析血清溶质载体家族7成员11（SLC7A11）、肉毒碱棕榈酰基转移酶1A（CPT1A）表达水平与宫颈癌（CC）患者临床病理特征及预后的关系。方法2020年2月至2021年5月于新疆医科大学第一附属医院治疗的114例CC患者作为CC组，同期纳入60例健康体检者作为对照组。采用实时荧光定量PCR（qRT-PCR）检测血清SLC7A11、CPT1A表达水平；分析CC患者血清SLC7A11、CPT1A表达水平与其临床病理特征的关系；采用ROC曲线评估血清SLC7A11 ...
任玉海, 钟笛, 木丽德尔
doaj  

Ferroptosis‐Driven Neuronal Damage Exacerbation in Diabetic Stroke: Implications of SLC7A11 Inhibition

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
The current study uncovered aggravated cerebral ischemic injury and neurological dysfunction following diabetic stroke, in which ferroptosis was involved. SLC7A11 expression was inhibited in the early stages of reperfusion during diabetic stroke, and both ferroptosis inhibitors and neuron‐specific enforced expression of SLC7A11 mitigated neuronal lipid
Siyuan Liu, Min Liu, Binbin Wang, Miao Sun, Huikai Yang, Mengyao Qu, Libin Ma, Likai Shi, Yuxiang Song, Peng Li, Lulu Zhou, Wugang Hou, Weidong Mi, Yulong Ma   +13 more
wiley   +1 more source

8-Chloro-adenosine inhibits breast cancer progression by inducing ferroptosis via the ADAR1/miR-101-3p/SLC7A11 axis. [PDF]

Cancer Cell Int
Hao M, Li Y, Zhang MM, Yin C, Gao ZD, Yang J, Jiang JN, Tu Z, Yang SY.   +8 more
europepmc   +1 more source

The multifaceted roles of the ACSL family in cancer: Metabolic reprogramming, ferroptosis regulation and tumour immune microenvironment remodelling

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
The acyl‐CoA synthetase long‐chain (ACSL) family consists of five members, which exhibit a synergistic effect in promoting tumour lipid metabolism for energy supply. Specifically, ACSL3 and ACSL4 have antagonistic effects on the mechanisms related to ferroptosis in tumour cells.
Haocai Li, Weijian Wang, Juncheng Zhan, Yuxiang Xiao, Xiaoping Chen, Chen Su, Peng Zhu   +6 more
wiley   +1 more source

Divergent roles of circMPP6 and its parental gene MPP6 in non-small cell lung cancer. [PDF]

Front Cell Dev Biol
Gao W, Pan F, Qiu K, Ou C, Tian F, Yu C.
europepmc   +1 more source

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

Food Frontiers, Volume 7, Issue 2, March 2026.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li, Qihui Zhu, Yang Li, Haiyu Zhao, Yi Bi, Chuanying Pan, Min Wang, Lin Han, Xianyong Lan   +8 more
wiley   +1 more source

The Mechanism and Regulation of Disulfidptosis and Its Role in Disease. [PDF]

Biomedicines
Wan Y, Jing M, Zhang L, Song Q, Ye X, Zhou Z, Yan W, Fu Y.   +7 more
europepmc   +1 more source

Wogonoside Modulates the Nrf2/SLC40A1 Signaling Axis to Combat Inflammatory Osteolysis

Food Frontiers, Volume 7, Issue 2, March 2026.
This study explores the potential of wogonoside, a flavonoid from Scutellaria baicalensis, for treating inflammatory osteolysis and provides compelling experimental evidence supporting its promise as a functional food ingredient to alleviate associated bone loss.
Siyuan Zhou, Haoyu Lian, Yuangang Su, Li Wang, Jiake Xu, Jinmin Zhao, Qian Liu   +6 more
wiley   +1 more source