Dihydroartemisinin Alleviates Neuronal Damage and Seizures in Epileptic Mice by Inhibiting Ferroptosis via the SIRT1/FOXO1/SLC7A11/GPX4 Pathway. [PDF]
CNS Neurosci TherYou Z +7 more
europepmc +1 more source
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Protect liver health and enhance growth performance: ensure safer, higher‐quality meat, and improve economic efficiency in poultry production. Heat stress induces liver injury through oxidative stress, ferroptosis, and mitochondrial dysfunction. Yinhuang oral liquid (YOL) mitigates these effects via multi‐target mechanisms, including activation of the ...
Zi‐Hao Li +7 more
wiley +1 more source
Lactate Dehydrogenase B delactylation promotes gastric cancer metastasis via enhancing glutathione-mediated resistance to ferroptosis. [PDF]
Cell Biol ToxicolXiao X, Yang Y, Yang Y, Zhao G.
europepmc +1 more source
Mast Cell‐Derived CXCL4: A Key Mediator of Ferroptosis and Cardiac Damage in Septic Cardiomyopathy
Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.ABSTRACT Background Septic cardiomyopathy (SCM) is a common and life‐threatening complication of severe sepsis, with high mortality due to unclear underlying mechanisms. CXCL4, a key pro‐inflammatory factor, is implicated in various heart diseases, while ferroptosis (iron and lipid hydrogen peroxide‐dependent regulated cell death) plays a crucial role ...
Jing Wei +3 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 3, March 2026.ABSTRACT Alveolar epithelial cell pyroptosis exacerbates inflammation and tissue damage by releasing inflammatory mediators, thereby promoting the development of acute lung injury (ALI). However, the fundamental mechanism underlying alveolar epithelial cell pyroptosis in ALI has not yet been elucidated. Lipopolysaccharide (LPS) was used to simulate ALI
Lei Wang +5 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 3, March 2026.ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most common non‐Hodgkin lymphoma and is an aggressive and highly heterogeneous tumor. Kaempferitrin (KPF) is a natural flavonoid glycoside that exerts a protective role in multiple human tumors. However, the impact of KPF on DLBCL remains unclear.
Han‐Shuo Zhang +3 more
wiley +1 more source
Sodium propionate alleviates bronchopulmonary dysplasia by inhibiting ferroptosis through the SLC7A11/GPX4 pathway in pulmonary endothelial cells. [PDF]
Respir ResXie A, Chen X, Bao Z, Yu P, Yu R.
europepmc +1 more source
RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets
MedComm, Volume 7, Issue 3, March 2026.RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin +9 more
wiley +1 more source
Rottlerin triggers dual degradation of SLC7A11 and GPX4 to drive ferroptosis and chemosensitization in hepatocellular carcinoma. [PDF]
Cell Death DiscovLuo H +9 more
europepmc +1 more source