Results 191 to 200 of about 19,150 (245)

Sestrin2 Mitigates Neuronal Ferroptosis Following Subarachnoid Hemorrhage via Orchestration of the AMPK/PGC1α/Nrf2 Signaling Axis. [PDF]

CNS Neurosci Ther
Zhang Y, Wan X, Zhang H, Chen Z, Xiao S, Wang W, Wang J, Zheng R, Chen X, Yang Y.   +9 more
europepmc   +1 more source

The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis

Phytotherapy Research, Volume 40, Issue 8, Page 5071-5089, August 2026.
ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang, YongJun Du, Yanmei Hou, Liangliang Hao, Zhen Chen, Haoyang Xie, Chuantao Zhang, Lei Li   +7 more
wiley   +1 more source

Peripheral Circulating Exosomes Induce Sepsis-associated Liver Injury by Up-regulating STAT1 to Promote Autophagy and Regulating the SLC7A11-GSH-GPX4 Axis to Promote Ferroptosis. [PDF]

Inflammation
Tang YJ, Du X, Yin B, Liu HY, Tang YJ, Zhang ZY, Meng QM, Zhang Y, Deng JL, Li Y, Yang PL, Kang K, Zhao MY, Gao Y.   +13 more
europepmc   +1 more source

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

Phytotherapy Research, Volume 40, Issue 8, Page 5119-5131, August 2026.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi, Renda Chahna, Francesca Maffei, Alma Martelli, Vincenzo Calderone, Carmela Fimognari, Eleonora Turrini   +6 more
wiley   +1 more source

UFM1 regulates ferroptosis in oral squamous cell carcinoma by stabilizing SLC7A11. [PDF]

Am J Cancer Res
Li G, Yang H, Guo J.
europepmc   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

The FEBS Journal, Volume 293, Issue 15, Page 4508-4532, August 2026.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump, Leja Perne, Špela Koren, Eva Jarc Jovičić, Nastja Feguš, Carina Pinto Kozmus, Michele Wölk, Kristyna Brejchova, Maria Fedorova, Ondrej Kuda, Toni Petan   +10 more
wiley   +1 more source

TRIM62 promotes osteoarthritis progression by facilitating GPX4 ubiquitination and chondrocyte ferroptosis. [PDF]

Am J Transl Res
Chen X, Zhang Y.
europepmc   +1 more source

Corylin Confers Vasoprotection via JDP2‐Nrf2 Antioxidant Axis against Chronic Kidney Disease‐Induced Smooth Muscle Cell Remodelling

Journal of Cellular and Molecular Medicine, Volume 30, Issue 16, August 2026.
ABSTRACT Vascular calcification is a pathological process involving vascular smooth muscle cells (VSMCs) phenotypic switching into osteoblast‐like cells within a calcium phosphate‐deposited environment. This transformation is a critical risk factor for cardiovascular morbidity and mortality in patients with hyperphosphatemia due to chronic kidney ...
Shang‐En Huang, Chih‐Le Lin, Kazunari K. Yokoyama, Kai‐Fang Hu, Bin‐Nan Wu, Zen‐Kong Dai, Meng‐Xuan Lin, Yu‐Hsin Tseng, Jong‐Hau Hsu, Jwu‐Lai Yeh   +9 more
wiley   +1 more source

Salvianic Acid A Regulates Ferroptosis by Activating the Nrf2-GPX4 Pathway Through EGFR to Protect Myocardial Ischemia-Reperfusion Injury. [PDF]

J Inflamm Res
Tu L, Lu Y, Liu X, Shen X.
europepmc   +1 more source